Wenyu Wu

Department of Nuclear Medicine,
Nanjing First Hospital

Nanjing Medical University

BIOGRAPHY

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PUBLICATIONS

A new and efficient synthesis of 6-O-methylscutellarein, the major metabolite of the natural medicine scutellarin.

Molecules (Basel, Switzerland) Jun, 2015 | Pubmed ID: 26042857

An Efficient Chemical Synthesis of Scutellarein: An in Vivo Metabolite of Scutellarin.

Molecules (Basel, Switzerland) Feb, 2016 | Pubmed ID: 26927039

Development and Structural Modification of BACE1 Inhibitors.

Molecules (Basel, Switzerland) Dec, 2016 | Pubmed ID: 28025519

Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative.

Molecules (Basel, Switzerland) Jun, 2017 | Pubmed ID: 28635646

A novel and efficient synthesis of phenanthrene derivatives via palladium/norbornadiene-catalyzed domino one-pot reaction.

Beilstein journal of organic chemistry , 2019 | Pubmed ID: 30800179

[Ga]Ga-NOTA-MAL-Cys-exendin-4, a potential GLP-1R targeted PET tracer for the detection of insulinoma.

Nuclear medicine and biology , 2019 | Pubmed ID: 31450071

Design, synthesis and evaluation of 2-amino-imidazol-4-one derivatives as potent β-site amyloid precursor protein cleaving enzyme 1 (BACE-1) inhibitors.

Bioorganic & medicinal chemistry letters Dec, 2019 | Pubmed ID: 31711785

Total synthesis, chemical modification and structure-activity relationship of bufadienolides.

European journal of medicinal chemistry Mar, 2020 | Pubmed ID: 31945667

Safety and tolerability of Ga-NT-20.3, a radiopharmaceutical for targeting neurotensin receptors, in patients with pancreatic ductal adenocarcinoma: the first in-human use.

European journal of nuclear medicine and molecular imaging Apr, 2021 | Pubmed ID: 33006657

Use of Chromogranin A for Monitoring Patients With Pancreatic Neuroendocrine Neoplasms.

Pancreas Jul, 2021 | Pubmed ID: 34347728

Smart I-Labeled Self-Illuminating Photosensitizers for Deep Tumor Therapy.

Angewandte Chemie (International ed. in English) Sep, 2021 | Pubmed ID: 34374188

An efficient strategy for digging protein-protein interactions for rational drug design - A case study with HIF-1α/VHL.

European journal of medicinal chemistry Jan, 2022 | Pubmed ID: 34638033

LDLR dysfunction induces LDL accumulation and promotes pulmonary fibrosis.

Clinical and translational medicine Jan, 2022 | Pubmed ID: 35083881

Ga-DOTA-NT-20.3 Neurotensin Receptor 1 PET Imaging as a Surrogate for Neuroendocrine Differentiation of Prostate Cancer.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine Sep, 2022 | Pubmed ID: 35177423

Lu-PSMA-I&T Radioligand Therapy for Treating Metastatic Castration-Resistant Prostate Cancer: A Single-Centre Study in East Asians.

Frontiers in oncology , 2022 | Pubmed ID: 35402274

Whole-body PET tracking of a d-dodecapeptide and its radiotheranostic potential for PD-L1 overexpressing tumors.

Acta pharmaceutica Sinica. B Mar, 2022 | Pubmed ID: 35530129

Antitumour effects of apatinib in progressive, metastatic differentiated thyroid cancer (DTC).

Endocrine Oct, 2022 | Pubmed ID: 35767182

Indoleamine 2,3-Dioxygenase Immune Status as a Potential Biomarker of Radioiodine Efficacy for Advanced Distant Metastatic Differentiated Thyroid Cancer.

Frontiers in oncology , 2022 | Pubmed ID: 35924153

Development and validation of Ga-PSMA-11 PET/CT-based radiomics model to detect primary prostate cancer.

EJNMMI research Sep, 2022 | Pubmed ID: 36175753

INSTITUTIONS

Nanjing Medical University

JOVE ARTICLES

Development of a ⁶⁸Gallium-Labeled D-Peptide PET Tracer for Imaging Programmed Death-Ligand 1 Expression

Lulu Zhang^*,1,

Siqi Zhang^*,2,

Wenyu Wu¹,

Xingkai Wang²,

Jieting Shen²,

Dongyuan Wang⁴,

Kuan Hu^*,2,3,

Ming-Rong Zhang^*,3,

Feng Wang^*,1,

Rui Wang^*,2

¹Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University,

²State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College,

³Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology,

⁴Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

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Wenyu Wu

Department of Nuclear Medicine,Nanjing First Hospital

Nanjing Medical University

Development of a 68Gallium-Labeled D-Peptide PET Tracer for Imaging Programmed Death-Ligand 1 Expression

Department of Nuclear Medicine,
Nanjing First Hospital

Development of a ⁶⁸Gallium-Labeled D-Peptide PET Tracer for Imaging Programmed Death-Ligand 1 Expression