Department of Neurosurgery
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Studying the heterogeneity of brain tumors using medium throughput LOH analysis.
Cytometry Jan, 2002 | Pubmed ID: 11774351
Correlations between magnetic resonance spectroscopy and image-guided histopathology, with special attention to radiation necrosis.
Neurosurgery Oct, 2002 | Pubmed ID: 12234397
Degradation of extracellular matrix protein tenascin-C by cathepsin B: an interaction involved in the progression of gliomas.
Biological chemistry Sep, 2002 | Pubmed ID: 12437133
Angiogenesis in glioma: molecular mechanisms and roadblocks to translation.
Cancer journal (Sudbury, Mass.) May-Jun, 2003 | Pubmed ID: 12952305
Phase 2 study of weekly irinotecan in adults with recurrent malignant glioma: final report of NABTT 97-11.
Neuro-oncology Jan, 2004 | Pubmed ID: 14769136
Associations among magnetic resonance spectroscopy, apparent diffusion coefficients, and image-guided histopathology with special attention to radiation necrosis.
Neurosurgery May, 2004 | Pubmed ID: 15113465
A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting.
Molecular therapy : the journal of the American Society of Gene Therapy Nov, 2004 | Pubmed ID: 15509513
Developing a brain tumor center.
Journal of neuro-oncology Aug-Sep, 2004 | Pubmed ID: 15527088
Assessment of brain tumor angiogenesis inhibitors using perfusion magnetic resonance imaging: quality and analysis results of a phase I trial.
Journal of magnetic resonance imaging : JMRI Dec, 2004 | Pubmed ID: 15558578
Analysis of glioma cell platinum response by metacomparison of two-dimensional chromatographic proteome profiles.
Molecular & cellular proteomics : MCP Jan, 2006 | Pubmed ID: 15951525
SDF-1 and CXCR4 are up-regulated by VEGF and contribute to glioma cell invasion.
Cancer letters May, 2006 | Pubmed ID: 15967572
Angiogenesis and apoptosis in glioma: two arenas for promising new therapies.
Journal of cellular biochemistry Sep, 2005 | Pubmed ID: 16052525
Phase 2 trial of copper depletion and penicillamine as antiangiogenesis therapy of glioblastoma.
Neuro-oncology Jul, 2005 | Pubmed ID: 16053699
A quantitative model of tumor-induced angiogenesis in the nude mouse.
Neurosurgery Aug, 2005 | Pubmed ID: 16094162
AMP-dependent protein kinase alpha 2 isoform promotes hypoxia-induced VEGF expression in human glioblastoma.
Glia May, 2006 | Pubmed ID: 16518831
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain.
Cancer cell Apr, 2006 | Pubmed ID: 16616334
Polynuclear platinum anticancer drugs are more potent than cisplatin and induce cell cycle arrest in glioma.
Neuro-oncology Jul, 2006 | Pubmed ID: 16723633
Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM).
Journal of neuro-oncology Dec, 2006 | Pubmed ID: 16773218
The effect of enzyme-inducing antiseizure drugs on the pharmacokinetics and tolerability of procarbazine hydrochloride.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2006 | Pubmed ID: 16951236
High-resolution global genomic survey of 178 gliomas reveals novel regions of copy number alteration and allelic imbalances.
Cancer research Oct, 2006 | Pubmed ID: 17018597
Phase II clinical and pharmacologic study of radiation therapy and carboxyamido-triazole (CAI) in adults with newly diagnosed glioblastoma multiforme.
Investigational new drugs Jun, 2007 | Pubmed ID: 17080256
A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin-fixed paraffin-embedded tissue.
Laboratory investigation; a journal of technical methods and pathology Apr, 2007 | Pubmed ID: 17260000
Proteomic comparison of oligodendrogliomas with and without 1pLOH.
Cancer biology & therapy Mar, 2007 | Pubmed ID: 17264672
2D/3D image fusion for accurate target localization and evaluation of a mask based stereotactic system in fractionated stereotactic radiotherapy of cranial lesions.
Medical physics Dec, 2006 | Pubmed ID: 17278807
Cerebellar tumors in pediatric patients: can they be differentiated using diffusion-weighted imaging?
Nature clinical practice. Neurology Feb, 2007 | Pubmed ID: 17279080
Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology May, 2007 | Pubmed ID: 17470857
Decrease of endogenous vascular endothelial growth factor may not affect glioma cell proliferation and invasion.
Journal of experimental therapeutics & oncology , 2007 | Pubmed ID: 17552362
Cloning and characterization of human RTVP-1b, a novel splice variant of RTVP-1 in glioma cells.
Biochemical and biophysical research communications Oct, 2007 | Pubmed ID: 17825796
Altered adenosine-to-inosine RNA editing in human cancer.
Genome research Nov, 2007 | Pubmed ID: 17908822
First-pass perfusion computed tomography: initial experience in differentiating recurrent brain tumors from radiation effects and radiation necrosis.
Neurosurgery Oct, 2007 | Pubmed ID: 17986939
Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas.
Molecular cancer research : MCR Jan, 2008 | Pubmed ID: 18184972
FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-kappaB signaling pathway.
Neoplasia (New York, N.Y.) Mar, 2008 | Pubmed ID: 18320068
GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis.
Neuro-oncology Jun, 2008 | Pubmed ID: 18403493
Phase I safety study of escalating doses of atrasentan in adults with recurrent malignant glioma.
Neuro-oncology Aug, 2008 | Pubmed ID: 18477765
Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma multiforme.
Expert opinion on investigational drugs Aug, 2008 | Pubmed ID: 18616418
Increased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells.
Journal of experimental & clinical cancer research : CR , 2008 | Pubmed ID: 18647407
Phase II preradiation R115777 (tipifarnib) in newly diagnosed GBM with residual enhancing disease.
Neuro-oncology Dec, 2008 | Pubmed ID: 18725460
Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Dec, 2008 | Pubmed ID: 18981465
Insulin-like growth factor binding protein 7 mediates glioma cell growth and migration.
Neoplasia (New York, N.Y.) Dec, 2008 | Pubmed ID: 19048112
Salvage reirradiation for recurrent glioblastoma with radiosurgery: radiographic response and improved survival.
Journal of neuro-oncology Apr, 2009 | Pubmed ID: 19066727
Bevacizumab and irinotecan treatment for progressive diffuse brainstem glioma: case report.
Journal of neuro-oncology Jul, 2009 | Pubmed ID: 19139822
Initial experience with bevacizumab treatment for biopsy confirmed cerebral radiation necrosis.
Journal of neuro-oncology Aug, 2009 | Pubmed ID: 19189055
Radiation sensitization of glioblastoma by cilengitide has unanticipated schedule-dependency.
International journal of cancer. Journal international du cancer Jun, 2009 | Pubmed ID: 19199360
Odyssey of hope: a physician's guide to communicating with brain tumor patients across the continuum of care.
Journal of neuro-oncology May, 2009 | Pubmed ID: 19357952
The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells.
International journal of cancer. Journal international du cancer Aug, 2009 | Pubmed ID: 19431142
Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Sep, 2009 | Pubmed ID: 19636006
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Oct, 2009 | Pubmed ID: 19720927
Can permeability measurements add to blood volume measurements in differentiating tumefactive demyelinating lesions from high grade gliomas using perfusion CT?
Journal of neuro-oncology May, 2010 | Pubmed ID: 19830525
The role of salvage reirradiation for malignant gliomas that progress on bevacizumab.
Journal of neuro-oncology May, 2010 | Pubmed ID: 19838627
Imaging response criteria for recurrent gliomas treated with bevacizumab: role of diffusion weighted imaging as an imaging biomarker.
Journal of neuro-oncology Feb, 2010 | Pubmed ID: 19859666
Gliosarcoma stem cells undergo glial and mesenchymal differentiation in vivo.
Stem cells (Dayton, Ohio) Feb, 2010 | Pubmed ID: 19937755
The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topics.
Journal of neuro-oncology Jan, 2010 | Pubmed ID: 19957013
The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal of neuro-oncology Jan, 2010 | Pubmed ID: 19957014
The role of prophylactic anticonvulsants in the management of brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal of neuro-oncology Jan, 2010 | Pubmed ID: 19957015
The role of retreatment in the management of recurrent/progressive brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal of neuro-oncology Jan, 2010 | Pubmed ID: 19957016
The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal of neuro-oncology Jan, 2010 | Pubmed ID: 19960227
The role of chemotherapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal of neuro-oncology Jan, 2010 | Pubmed ID: 19960229
The role of surgical resection in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal of neuro-oncology Jan, 2010 | Pubmed ID: 19960230
The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal of neuro-oncology Jan, 2010 | Pubmed ID: 19960231
Rebound tumour progression after the cessation of bevacizumab therapy in patients with recurrent high-grade glioma.
Journal of neuro-oncology Sep, 2010 | Pubmed ID: 20151176
Treatment induced necrosis versus recurrent/progressing brain tumor: going beyond the boundaries of conventional morphologic imaging.
Journal of neuro-oncology Oct, 2010 | Pubmed ID: 20179990
Phase 1 clinical trial of bortezomib in adults with recurrent malignant glioma.
Journal of neuro-oncology Oct, 2010 | Pubmed ID: 20213332
Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Apr, 2010 | Pubmed ID: 20231676
Phase I/II dose escalation trial of concurrent temozolomide and whole brain radiation therapy for multiple brain metastasis.
Journal of neuro-oncology Nov, 2010 | Pubmed ID: 20431907
A phase I/II trial and pharmacokinetic study of ixabepilone in adult patients with recurrent high-grade gliomas.
Journal of neuro-oncology Nov, 2010 | Pubmed ID: 20449631
An integrative approach for in silico glioma research.
IEEE transactions on bio-medical engineering Oct, 2010 | Pubmed ID: 20656651
Tumor vascular leakiness and blood volume estimates in oligodendrogliomas using perfusion CT: an analysis of perfusion parameters helping further characterize genetic subtypes as well as differentiate from astroglial tumors.
Journal of neuro-oncology Apr, 2011 | Pubmed ID: 20680399
Targeting integrins in malignant glioma.
Targeted oncology Sep, 2010 | Pubmed ID: 20820929
Predicting survival in glioblastomas using diffusion tensor imaging metrics.
Journal of magnetic resonance imaging : JMRI Oct, 2010 | Pubmed ID: 20882608
Response as a predictor of survival in patients with recurrent glioblastoma treated with bevacizumab.
Neuro-oncology Jan, 2011 | Pubmed ID: 21084434
Corticosteroid use in patients with glioblastoma at first or second relapse treated with bevacizumab in the BRAIN study.
The oncologist , 2010 | Pubmed ID: 21147867
Proteasome inhibitors sensitize glioma cells and glioma stem cells to TRAIL-induced apoptosis by PKCε-dependent downregulation of AKT and XIAP expressions.
Cellular signalling Aug, 2011 | Pubmed ID: 21440622
Recurrent high-grade glioma: a diagnostic and therapeutic challenge.
Expert review of neurotherapeutics Apr, 2011 | Pubmed ID: 21469924
Phase I and pharmacokinetic study of COL-3 in patients with recurrent high-grade gliomas.
Journal of neuro-oncology Nov, 2011 | Pubmed ID: 21547395
Neurocognitive function in patients with recurrent glioblastoma treated with bevacizumab.
Neuro-oncology Jun, 2011 | Pubmed ID: 21558074
Correlation of immunohistologic and perfusion vascular parameters with MR contrast enhancement using image-guided biopsy specimens in gliomas.
Academic radiology Aug, 2011 | Pubmed ID: 21718954
Cilengitide induces autophagy-mediated cell death in glioma cells.
Neuro-oncology Aug, 2011 | Pubmed ID: 21788343
Differentiating treatment-induced necrosis from recurrent/progressive brain tumor using nonmodel-based semiquantitative indices derived from dynamic contrast-enhanced T1-weighted MR perfusion.
Neuro-oncology Sep, 2011 | Pubmed ID: 21803763
Model selection for DCE-T1 studies in glioblastoma.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Jul, 2012 | Pubmed ID: 22127934
Prediction of glioblastoma multiform response to bevacizumab treatment using multi-parametric MRI.
PloS one , 2012 | Pubmed ID: 22253835
Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas.
Cell cycle (Georgetown, Tex.) Feb, 2012 | Pubmed ID: 22274399
Integrated morphologic analysis for the identification and characterization of disease subtypes.
Journal of the American Medical Informatics Association : JAMIA Mar-Apr, 2012 | Pubmed ID: 22278382
A prognostic gene expression signature in infratentorial ependymoma.
Acta neuropathologica May, 2012 | Pubmed ID: 22322993
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 22323597
Phase I study of terameprocol in patients with recurrent high-grade glioma.
Neuro-oncology Apr, 2012 | Pubmed ID: 22323663
Development of a novel animal model to differentiate radiation necrosis from tumor recurrence.
Journal of neuro-oncology Jul, 2012 | Pubmed ID: 22407176
Apparent diffusion coefficient histogram analysis stratifies progression-free and overall survival in patients with recurrent GBM treated with bevacizumab: a multi-center study.
Journal of neuro-oncology Jul, 2012 | Pubmed ID: 22426926
DW-MRI as a biomarker to compare therapeutic outcomes in radiotherapy regimens incorporating temozolomide or gemcitabine in glioblastoma.
PloS one , 2012 | Pubmed ID: 22536446
Segmentation of corpus callosum using diffusion tensor imaging: validation in patients with glioblastoma.
BMC medical imaging , 2012 | Pubmed ID: 22591335
Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma.
Science (New York, N.Y.) Jul, 2012 | Pubmed ID: 22837387
A nano-sized PARACEST-fluorescence imaging contrast agent facilitates and validates in vivo CEST MRI detection of glioma.
Nanomedicine (London, England) Dec, 2012 | Pubmed ID: 22891866
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.
Cancer cell Oct, 2012 | Pubmed ID: 23079654
Genomic mapping and survival prediction in glioblastoma: molecular subclassification strengthened by hemodynamic imaging biomarkers.
Radiology Apr, 2013 | Pubmed ID: 23238158
NABTT 0502: a phase II and pharmacokinetic study of erlotinib and sorafenib for patients with progressive or recurrent glioblastoma multiforme.
Neuro-oncology Apr, 2013 | Pubmed ID: 23328813
Phase I study of GRN1005 in recurrent malignant glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research Mar, 2013 | Pubmed ID: 23349317
A phase I/II trial of pazopanib in combination with lapatinib in adult patients with relapsed malignant glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research Feb, 2013 | Pubmed ID: 23363814
MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor.
PloS one , 2013 | Pubmed ID: 23390502
MR imaging predictors of molecular profile and survival: multi-institutional study of the TCGA glioblastoma data set.
Radiology May, 2013 | Pubmed ID: 23392431
Morphologic MRI features, diffusion tensor imaging and radiation dosimetric analysis to differentiate pseudo-progression from early tumor progression.
Journal of neuro-oncology May, 2013 | Pubmed ID: 23417357
Histological predictors of outcome in ependymoma are dependent on anatomic site within the central nervous system.
Brain pathology (Zurich, Switzerland) Sep, 2013 | Pubmed ID: 23452038
Prognostic vascular imaging biomarkers in high-grade gliomas: tumor permeability as an adjunct to blood volume estimates.
Academic radiology Apr, 2013 | Pubmed ID: 23498990
The Corpus Callosum Wallerian Degeneration in the Unilateral Brain Tumors: Evaluation with Diffusion Tensor Imaging (DTI).
Journal of clinical and diagnostic research : JCDR Feb, 2013 | Pubmed ID: 23543618
Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal.
Oncotarget Feb, 2013 | Pubmed ID: 23548312
MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1.
Oncotarget May, 2013 | Pubmed ID: 23714687
Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2013 | Pubmed ID: 23864165
The integrated landscape of driver genomic alterations in glioblastoma.
Nature genetics Oct, 2013 | Pubmed ID: 23917401
Phase III randomized trial comparing the efficacy of cediranib as monotherapy, and in combination with lomustine, versus lomustine alone in patients with recurrent glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Sep, 2013 | Pubmed ID: 23940216
Double minute chromosomes in glioblastoma multiforme are revealed by precise reconstruction of oncogenic amplicons.
Cancer research Oct, 2013 | Pubmed ID: 23940299
Subcurative radiation significantly increases proliferation, invasion, and migration of primary GBM in vivo.
Chinese journal of cancer Sep, 2013 | Pubmed ID: 24016393
The somatic genomic landscape of glioblastoma.
Cell Oct, 2013 | Pubmed ID: 24120142
Patterns of failure after radiosurgery to two different target volumes of enhancing lesions with and without FLAIR abnormalities in recurrent glioblastoma multiforme.
Journal of neuro-oncology Oct, 2013 | Pubmed ID: 24173682
Machine-based morphologic analysis of glioblastoma using whole-slide pathology images uncovers clinically relevant molecular correlates.
PloS one , 2013 | Pubmed ID: 24236209
Glioblastoma cell enrichment is critical for analysis of phosphorylated drug targets and proteomic-genomic correlations.
Cancer research Dec, 2013 | Pubmed ID: 24346432
Cilengitide-induced temporal variations in transvascular transfer parameters of tumor vasculature in a rat glioma model: identifying potential MRI biomarkers of acute effects.
PloS one , 2013 | Pubmed ID: 24376814
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