James J. Hickman

Electrophysiological and morphological characterization of rat embryonic motoneurons in a defined system.

Construction of high-density bacterial colony arrays and patterns by the ink-jet method.

Long-term culture of embryonic rat cardiomyocytes on an organosilane surface in a serum-free medium.

Total protein determinations by particle beam/hollow cathode optical emission spectroscopy (PB/HC-OES) system III: investigation of carrier salts for enhanced particle transport.

A new interpretation of serum albumin surface passivation.

Adult rat spinal cord culture on an organosilane surface in a novel serum-free medium.

Toxin detection based on action potential shape analysis using a realistic mathematical model of differentiated NG108-15 cells.

A defined system to allow skeletal muscle differentiation and subsequent integration with silicon microstructures.

Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons.

Photolithographic patterning of C2C12 myotubes using vitronectin as growth substrate in serum-free medium.

Differentiation of skeletal muscle and integration of myotubes with silicon microstructures using serum-free medium and a synthetic silane substrate.

Temporal neurotransmitter conditioning restores the functional activity of adult spinal cord neurons in long-term culture.

Tissue engineering intrafusal fibers: dose- and time-dependent differentiation of nuclear bag fibers in a defined in vitro system using neuregulin 1-beta-1.

Electrophysiological and immunocytochemical characterization of DRG neurons on an organosilane surface in serum-free medium.

Synaptic connectivity in engineered neuronal networks.

Modeling of action potential generation in NG108-15 cells.

Growth and electrophysiological properties of rat embryonic cardiomyocytes on hydroxyl- and carboxyl-modified surfaces.

Regeneration and characterization of adult mouse hippocampal neurons in a defined in vitro system.

Node of Ranvier formation on motoneurons in vitro.

Developing a novel serum-free cell culture model of skeletal muscle differentiation by systematically studying the role of different growth factors in myotube formation.

Electrophysiological characterization of embryonic hippocampal neurons cultured in a 3D collagen hydrogel.

Skeletal muscle tissue engineering: a maturation model promoting long-term survival of myotubes, structural development of the excitation-contraction coupling apparatus and neonatal myosin heavy chain expression.

Engineering a titanium and polycaprolactone construct for a biocompatible interface between the body and artificial limb.

Analysis of toxin-induced changes in action potential shape for drug development.

Altered calcium dynamics in cardiac cells grown on silane-modified surfaces.

A new target for amyloid beta toxicity validated by standard and high-throughput electrophysiology.

Biomaterial Surface patterning of self assembled monolayers for controlling neuronal cell behavior.

A defined long-term in vitro tissue engineered model of neuromuscular junctions.

Addition of glutamate to serum-free culture promotes recovery of electrical activity in adult hippocampal neurons in vitro.

Coexpression of glutamate vesicular transporter (VGLUT1) and choline acetyltransferase (ChAT) proteins in fetal rat hippocampal neurons in culture.

Tissue engineering the mechanosensory circuit of the stretch reflex arc: sensory neuron innervation of intrafusal muscle fibers.

Highly sensitive thermal detection of thrombin using aptamer-functionalized phase change nanoparticles.

Patterned cardiomyocytes on microelectrode arrays as a functional, high information content drug screening platform.

Neuromuscular junction formation between human stem cell-derived motoneurons and human skeletal muscle in a defined system.

Whispering gallery mode biosensor quantification of fibronectin adsorption kinetics onto alkylsilane monolayers and interpretation of resultant cellular response.

Small Molecule Induction of Human Umbilical Stem Cells into MBP-positive Oligodendrocytes in a Defined Three-Dimensional Environment.

Tissue engineering the monosynaptic circuit of the stretch reflex arc with co-culture of embryonic motoneurons and proprioceptive sensory neurons.

Microfabricated mammalian organ systems and their integration into models of whole animals and humans.

Rat Cortical Oligodendrocyte-Embryonic Motoneuron Co-Culture: An In Vitro Axon-Oligodendrocyte Interaction Model.

Derivation of sensory neurons and neural crest stem cells from human neural progenitor hNP1.

Two cell circuits of oriented adult hippocampal neurons on self-assembled monolayers for use in the study of neuronal communication in a defined system.

A CONTINUUM HARD-SPHERE MODEL OF PROTEIN ADSORPTION.

Myelination and node of Ranvier formation on sensory neurons in a defined in vitro system.

How multi-organ microdevices can help foster drug development.

Microphysiological systems and low-cost microfluidic platform with analytics.

Using physiologically-based pharmacokinetic-guided "body-on-a-chip" systems to predict mammalian response to drug and chemical exposure.

Synaptic connectivity in engineered neuronal networks.

Modeling of action potential generation in NG108-15 cells.

A phenotypic culture system for the molecular analysis of CNS myelination in the spinal cord.

Toward in vitro models of brain structure and function.