Department of Medicine,
Division of Regenerative Medicine,
Department of Medicine, Division of Regenerative Medicine,
Division of Regenerative Medicine, Department of Medicine
Dr. Tang holds an MD degree from the Wannan Medical College, Wuhu, China; a Master degree in Immunology from Shanghai Medical College Fudan University; and a PhD degree in Microbiology and Immunology from the University of Arizona.
Following medical school, Dr. Tang practiced medicine as a radiologist for 2 years in Huangshan City People’s Hospital, Huangshan, Anhui province, China. After receiving his Master degree, he was appointed as a lecturer for 4 years in the Department of Immunology at Shanghai Medical College, Fudan University. After obtaining his PhD degree from the University of Arizona, Dr. Tang joined as a postdoctoral fellow Dr. Vipin Kumar’s research laboratory at Torrey Pines Institute for Molecular Studies in San Diego, California, where he remained for 4 years. Later he accepted a Research Associate position in the laboratory of Dr. Harvey Cantor at the Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts. After 3.5 years at Harvard, he became a faculty member at the University of Texas, El Paso, Texas where he stayed for 3 years before joining as an Assistant Research Professor and then Associate Research Professor, for a total of 6 years, the Division of Regenerative Medicine, Department of Medicine, School of Medicine at Loma Linda University in California. Dr. Tang joined the Long Island University College of Veterinary Medicine in September 2019.
Dr. Tang has considerable teaching experience. He has taught undergraduate and graduate students, medical students, and other professional students. He has developed syllabi and directed courses mainly in immunology. During his interactions with students, Dr. Tang strives to convey his passion for the discipline and to promote a learning environment that fosters student participation and small group discussion. Dr. Tang often emphasizes essential basic science concepts into clinically relevant scenarios that can be easily understood by students with different levels of knowledge.
Dr. Tang’s research interests include regulatory T (Treg) cells and the role of immune system in tissue repair. In the area of Treg cells, he is interested in the roles of 1,25(OH)2D (i.e. the active vitamin D metabolite) and retinoic acid (RA, i.e. the active vitamin A metabolite) in the induction of Treg cells and in the treatment of immune-mediated diseases through tissue-specific delivery of these two molecules. In addition, he is interested in the immune regulatory mechanisms of Qa-1(HLA-E in human)-restricted CD8 T cells. In the area of tissue repair, he is interested in the role of the immune system in stem cells. Such role may include stem cell recruitment, priming, and differentiation. The ultimate goals of the above studies are to develop novel therapies for diseases with improved safety and efficacy.
Cloning and characterization of a novel Drosophila stress induced DNase.
PloS one , 2014 | Pubmed ID: 25083901
Targeted 25-hydroxyvitamin D3 1α-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice.
Molecular therapy : the journal of the American Society of Gene Therapy Feb, 2015 | Pubmed ID: 25327179
MicroRNA223 promotes pathogenic T-cell development and autoimmune inflammation in central nervous system in mice.
Immunology Aug, 2016 | Pubmed ID: 27083389
Targeting Non-classical Myelin Epitopes to Treat Experimental Autoimmune Encephalomyelitis.
Scientific reports Oct, 2016 | Pubmed ID: 27796368
Application of vitamin D and vitamin D analogs in acute myelogenous leukemia.
Experimental hematology Feb, 2017 | Pubmed ID: 28174131
Dendritic cells, engineered to overexpress 25-hydroxyvitamin D 1α-hydroxylase and pulsed with a myelin antigen, provide myelin-specific suppression of ongoing experimental allergic encephalomyelitis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2017 | Pubmed ID: 28363955
Deficient arginase II expression without alteration in arginase I expression attenuated experimental autoimmune encephalomyelitis in mice.
Immunology 09, 2018 | Pubmed ID: 29574762
1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites.
JCI insight 09, 2018 | Pubmed ID: 30185660
In Vivo Generation of Gut-Homing Regulatory T Cells for the Suppression of Colitis.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2019 | Pubmed ID: 31053627
Cyclooxygenase 2 augments osteoblastic but suppresses chondrocytic differentiation of CD90 skeletal stem cells in fracture sites.
Science advances 07, 2019 | Pubmed ID: 31392271
Towards Clinical Translation of CD8 Regulatory T Cells Restricted by Non-Classical Major Histocompatibility Complex Ib Molecules.
International journal of molecular sciences Sep, 2019 | Pubmed ID: 31569411
Mechanistic study of the cause of decreased blood 1,25-Dihydroxyvitamin D in sepsis.
BMC infectious diseases Dec, 2019 | Pubmed ID: 31791247
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