Benyamin Rosental

The Shraga Segal Department of Microbiology,
Immunology,
and Genetics,
Faculty of Health Sciences,
and Regenerative Medicine and Stem Cell Research Center,
The Shraga Segal Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, and Regenerative Medicine and Stem Cell Research Center

Ben Gurion University of the Negev

BIOGRAPHY

I conducted my postdoctoral research at Stanford University, Institute of Stem Cells, School of Medicine, and Stanford Hopkins Marine Station. My Ph.D. research was in cancer, viral, and pregnancy immunology. During my Postdoctoral research, I was working on immune system histocompatibility and stem cell transplantation using a unique aquatic protochordate model.

The Rosental laboratory is investigating the immune mechanisms of cellular recognition and histocompatibility. This includes immune responses in transplantation with an emphasis on stem cell transplantation. We study basic research on understanding immune mechanisms into translational medical research. We work on the immune system and stem cells with diverse organisms such as humans, tunicates, planarians, and corals.

PUBLICATIONS

NKp44 receptor mediates interaction of the envelope glycoproteins from the West Nile and dengue viruses with NK cells.

Journal of immunology (Baltimore, Md. : 1950) Aug, 2009 | Pubmed ID: 19635919

Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44.

Journal of immunology (Baltimore, Md. : 1950) Dec, 2011 | Pubmed ID: 22021614

Upregulation of MHC class I expression following dengue virus infection: the mechanism at the promoter level.

Expert review of anti-infective therapy Mar, 2012 | Pubmed ID: 22397562

Human NK cell recognition of target cells in the prism of natural cytotoxicity receptors and their ligands.

Journal of immunotoxicology Jul-Sep, 2012 | Pubmed ID: 22524686

Dimerization of NKp46 receptor is essential for NKp46-mediated lysis: characterization of the dimerization site by epitope mapping.

Journal of immunology (Baltimore, Md. : 1950) Jun, 2012 | Pubmed ID: 22615207

Glycans in sera of amyotrophic lateral sclerosis patients and their role in killing neuronal cells.

PloS one , 2012 | Pubmed ID: 22666317

A novel mechanism for cancer cells to evade immune attack by NK cells: The interaction between NKp44 and proliferating cell nuclear antigen.

Oncoimmunology Jul, 2012 | Pubmed ID: 22754791

Dual fluorescent labelling of the human malaria parasite Plasmodium falciparum for the analysis of the ABC type transporter pfmdr2.

Malaria journal Nov, 2012 | Pubmed ID: 23137170

Genome-Wide siRNA Screen Reveals a New Cellular Partner of NK Cell Receptor KIR2DL4: Heparan Sulfate Directly Modulates KIR2DL4-Mediated Responses.

Journal of immunology (Baltimore, Md. : 1950) Nov, 2013 | Pubmed ID: 24127555

An NCR1-based chimeric receptor endows T-cells with multiple anti-tumor specificities.

Oncotarget Nov, 2014 | Pubmed ID: 25431955

First Trimester Pregnancy Loss and the Expression of Alternatively Spliced NKp30 Isoforms in Maternal Blood and Placental Tissue.

Frontiers in immunology , 2015 | Pubmed ID: 26082773

Survival in acute myeloid leukemia is associated with NKp44 splice variants.

Oncotarget May, 2016 | Pubmed ID: 27102296

NKp44 and NKp30 splice variant profiles in decidua and tumor tissues: a comparative viewpoint.

Oncotarget Oct, 2016 | Pubmed ID: 27765926

Complex mammalian-like haematopoietic system found in a colonial chordate.

Nature 12, 2018 | Pubmed ID: 30518860

Individual Sea Urchin Coelomocytes Undergo Somatic Immune Gene Diversification.

Frontiers in immunology , 2019 | Pubmed ID: 31244844

Evolutionary perspective on the hematopoietic system through a colonial chordate: allogeneic immunity and hematopoiesis.

Current opinion in immunology Feb, 2020 | Pubmed ID: 31954962

INSTITUTIONS

Ben Gurion University of the Negev

JOVE ARTICLES

Fluorescence-Activated Cell Sorting for the Isolation of Scleractinian Cell Populations

Grace A. Snyder¹,

William E. Browne²,

Nikki Traylor-Knowles^*,1,

Benyamin Rosental^*,3

¹Department of Marine Biology and Ecology, Rosenstiel School of Marine and Atmospheric Science, University of Miami,

²Department of Biology, University of Miami,

³The Shraga Segal Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, and Regenerative Medicine and Stem Cell Research Center, Ben Gurion University of the Negev

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