Department of Microbiology,
Li Ka Shing Faculty of Medicine,
Department of Microbiology, Li Ka Shing Faculty of Medicine
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Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response.
Virology Apr, 2014 | Pubmed ID: 24725946
Functional variants regulating LGALS1 (Galectin 1) expression affect human susceptibility to influenza A(H7N9).
Scientific reports Feb, 2015 | Pubmed ID: 25687228
Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza.
The Journal of infectious diseases Oct, 2015 | Pubmed ID: 25904605
PExFInS: An Integrative Post-GWAS Explorer for Functional Indels and SNPs.
Scientific reports Nov, 2015 | Pubmed ID: 26612672
Amino acid substitutions V63I or A37S/I61T/V63I/V100A in the PA N-terminal domain increase the virulence of H7N7 influenza A virus.
Scientific reports 11, 2016 | Pubmed ID: 27886255
PAN substitutions A37S, A37S/I61T and A37S/V63I attenuate the replication of H7N7 influenza A virus by impairing the polymerase and endonuclease activities.
The Journal of general virology Mar, 2017 | Pubmed ID: 28113045
Antibody-Dependent Cell-Mediated Cytotoxicity Epitopes on the Hemagglutinin Head Region of Pandemic H1N1 Influenza Virus Play Detrimental Roles in H1N1-Infected Mice.
Frontiers in immunology , 2017 | Pubmed ID: 28377769
Large-scale sequence analysis reveals novel human-adaptive markers in PB2 segment of seasonal influenza A viruses.
Emerging microbes & infections Mar, 2018 | Pubmed ID: 29593225
Differentiated human airway organoids to assess infectivity of emerging influenza virus.
Proceedings of the National Academy of Sciences of the United States of America 06, 2018 | Pubmed ID: 29891677
Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza.
Nature communications 06, 2018 | Pubmed ID: 29907765
Identification and characterization of GLDC as host susceptibility gene to severe influenza.
EMBO molecular medicine 01, 2019 | Pubmed ID: 30498026
Establishment of a lethal aged mouse model of human respiratory syncytial virus infection.
Antiviral research 01, 2019 | Pubmed ID: 30503888
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target.
Nature communications 01, 2019 | Pubmed ID: 30631056
Activation of C-Type Lectin Receptor and (RIG)-I-Like Receptors Contributes to Proinflammatory Response in Middle East Respiratory Syndrome Coronavirus-Infected Macrophages.
The Journal of infectious diseases 02, 2020 | Pubmed ID: 31562757
Infection of bat and human intestinal organoids by SARS-CoV-2.
Nature medicine 07, 2020 | Pubmed ID: 32405028
Natural Transmission of Bat-like Severe Acute Respiratory Syndrome Coronavirus 2 Without Proline-Arginine-Arginine-Alanine Variants in Coronavirus Disease 2019 Patients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 07, 2021 | Pubmed ID: 32649739
A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2.
Nature communications 08, 2020 | Pubmed ID: 32843628
Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target.
Emerging microbes & infections Dec, 2020 | Pubmed ID: 33179566
Development of Three-Dimensional Human Intestinal Organoids as a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of Enteroviruses.
Biomedicines Jan, 2021 | Pubmed ID: 33477611
Human Intestinal Organoids Recapitulate Enteric Infections of Enterovirus and Coronavirus.
Stem cell reports 03, 2021 | Pubmed ID: 33626333
Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies.
Cell host & microbe 04, 2021 | Pubmed ID: 33657424
STAT2-dependent restriction of Zika virus by human macrophages but not dendritic cells.
Emerging microbes & infections Dec, 2021 | Pubmed ID: 33979266
Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity.
Science advances 06, 2021 | Pubmed ID: 34134991
Miltoncostaea marina gen. nov. sp. nov., and Miltoncostaea oceani sp. nov., a novel deep branching phylogenetic lineage within the class Thermoleophilia isolated from marine environments, and proposal of Miltoncostaeaceae fam. nov. and Miltoncostaeales ord. nov.
Systematic and applied microbiology Jul, 2021 | Pubmed ID: 34157594
Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening protective immunity.
EBioMedicine Aug, 2021 | Pubmed ID: 34332295
SPINK6 inhibits human airway serine proteases and restricts influenza virus activation.
EMBO molecular medicine 01, 2022 | Pubmed ID: 34826211
sp. nov., a thermophilic bacterium isolated from deep sea sediment in the South China Sea.
International journal of systematic and evolutionary microbiology Dec, 2021 | Pubmed ID: 34904940
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