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SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1.
Journal of cell science Dec, 2015 | Pubmed ID: 26483383
Protein Kinase C Enzymes in the Hematopoietic and Immune Systems.
Annual review of immunology May, 2016 | Pubmed ID: 27168244
Phosphotyrosine-dependent interaction between the kinases PKCθ and Zap70 promotes proximal TCR signaling.
Science signaling Apr, 2019 | Pubmed ID: 30992398
pH-sensitive anti-CTLA4 antibodies: yes to efficacy, no to toxicity.
Cell research Aug, 2019 | Pubmed ID: 31300731
Protein Kinase C-η Deficiency Does Not Impair Antiviral Immunity and CD8 T Cell Activation.
Journal of immunology (Baltimore, Md. : 1950) , | Pubmed ID: 32198145
T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.
eLife Jun, 2021 | Pubmed ID: 34110283
CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition.
Nature communications Jun, 2021 | Pubmed ID: 34162836
Leveraging the Treg-intrinsic CTLA4-PKCη signaling pathway for cancer immunotherapy.
Journal for immunotherapy of cancer , | Pubmed ID: 34588224
La Jolla Institute for Immunology
Hsin Yu Liu1,
Amnon Altman1,
Ann J. Canonigo-Balancio1,
Michael Croft1
1, La Jolla Institute for Immunology
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