National Engineering Research Center of Immunological Products,
Department of Microbiology and Biochemical Pharmacy,
National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy
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Expression, purification, and characterization of recombinant human interleukin 24 in Escherichia coli.
Protein expression and purification Jun, 2007 | Pubmed ID: 17292626
[Techniques of separation and identification of enterohemorrhagic Escherichia coli O157 in laboratory].
Wei sheng yan jiu = Journal of hygiene research Mar, 2007 | Pubmed ID: 17555111
Engineering an anti-Stx2 antibody to control severe infections of EHEC O157:H7.
Immunology letters Dec, 2008 | Pubmed ID: 19007817
Functional identification of HugZ, a heme oxygenase from Helicobacter pylori.
BMC microbiology , 2008 | Pubmed ID: 19091096
Identification of small noncoding RNAs in Helicobacter pylori by a bioinformatics-based approach.
Current microbiology Mar, 2009 | Pubmed ID: 19123032
Enterohemorrhagic Escherichia coli trivalent recombinant vaccine containing EspA, intimin and Stx2 induces strong humoral immune response and confers protection in mice.
Microbes and infection Sep, 2009 | Pubmed ID: 19427397
Cloning a truncated fragment (stx2a(1)) of the shiga-like toxin 2A (1) subunit of EHEC O157:H7: candidate immunogen for a subunit vaccine.
Molecular biotechnology Sep, 2009 | Pubmed ID: 19434524
Protection from high-fat-diet-induced impaired glucose tolerance in female Sprague-Dawley rats.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology Jul, 2009 | Pubmed ID: 19903045
Crystallization and preliminary crystallographic studies of a flavin-dependent thymidylate synthase from Helicobacter pylori.
Acta crystallographica. Section F, Structural biology and crystallization communications May, 2010 | Pubmed ID: 20445247
Up-regulated microRNA-146a negatively modulate Helicobacter pylori-induced inflammatory response in human gastric epithelial cells.
Microbes and infection Oct, 2010 | Pubmed ID: 20542134
Crystallization and preliminary crystallographic studies of the C-terminal domain of outer membrane protein A from enterohaemorrhagic Escherichia coli.
Acta crystallographica. Section F, Structural biology and crystallization communications Aug, 2010 | Pubmed ID: 20693671
Characterization of enterohemorrhagic Escherichia coli O157:H7 00B015: a Shiga toxin producing but virulence-attenuated isolate.
Canadian journal of microbiology Aug, 2010 | Pubmed ID: 20725127
Fusion expression and immunogenicity of Bordetella pertussis PTS1-FHA protein: implications for the vaccine development.
Molecular biology reports Mar, 2011 | Pubmed ID: 20878241
Crystal structure of HugZ, a novel heme oxygenase from Helicobacter pylori.
The Journal of biological chemistry Jan, 2011 | Pubmed ID: 21030596
Crystal structure of EHEC intimin: insights into the complementarity between EPEC and EHEC.
PloS one , 2010 | Pubmed ID: 21179574
Crystallization and preliminary X-ray studies of native and mutant intimin from enterohaemorrhagic Escherichia coli.
Acta crystallographica. Section F, Structural biology and crystallization communications Jan, 2011 | Pubmed ID: 21206020
Expression, crystallization and preliminary crystallographic study of octaprenyl pyrophosphate synthase from Helicobacter pylori.
Acta crystallographica. Section F, Structural biology and crystallization communications Feb, 2011 | Pubmed ID: 21301101
Crystallization and preliminary crystallographic studies of Helicobacter pylori arginase.
Acta crystallographica. Section F, Structural biology and crystallization communications Jun, 2011 | Pubmed ID: 21636918
Vaccination of attenuated EIS-producing Salmonella induces protective immunity against enterohemorrhagic Escherichia coli in mice.
Vaccine Oct, 2011 | Pubmed ID: 21807051
Genotyping analysis of Helicobacter pylori using multiple-locus variable-number tandem-repeats analysis in five regions of China and Japan.
BMC microbiology Sep, 2011 | Pubmed ID: 21888662
Crystal structure of Campylobacter jejuni ChuZ: a split-barrel family heme oxygenase with a novel heme-binding mode.
Biochemical and biophysical research communications Nov, 2011 | Pubmed ID: 22020097
Expression, purification and characterization of arginase from Helicobacter pylori in its apo form.
PloS one , 2011 | Pubmed ID: 22028830
Crystallization and preliminary crystallographic studies of Campylobacter jejuni ChuZ, a member of a novel haem oxygenase family.
Acta crystallographica. Section F, Structural biology and crystallization communications Oct, 2011 | Pubmed ID: 22102034
Identification of antigen-specific antibody responses associated with upper genital tract pathology in mice infected with Chlamydia muridarum.
Infection and immunity Mar, 2012 | Pubmed ID: 22158739
Mapping immunodominant antigens and H-2-linked antibody responses in mice urogenitally infected with Chlamydia muridarum.
Microbes and infection / Institut Pasteur Jul, 2012 | Pubmed ID: 22421110
Crystal structure of a flavin-dependent thymidylate synthase from Helicobacter pylori strain 26695.
Protein and peptide letters Nov, 2012 | Pubmed ID: 22512654
Increased circulating Th22 and Th17 cells are associated with tumor progression and patient survival in human gastric cancer.
Journal of clinical immunology Dec, 2012 | Pubmed ID: 22760549
Genome of Helicobacter pylori strain XZ274, an isolate from a tibetan patient with gastric cancer in China.
Journal of bacteriology Aug, 2012 | Pubmed ID: 22815458
Crystal structure of TNF-α-inducing protein from Helicobacter pylori in active form reveals the intrinsic molecular flexibility for unique DNA-binding.
PloS one , 2012 | Pubmed ID: 22860022
Identification of a novel linear epitope in tetanus toxin recognized by a protective monoclonal antibody: implications for vaccine design.
Vaccine Oct, 2012 | Pubmed ID: 22889825
Modeling studies with Helicobacter pylori octaprenyl pyrophosphate synthase reveal the enzymatic mechanism of trans-prenyltransferases.
The international journal of biochemistry & cell biology Dec, 2012 | Pubmed ID: 22982238
Helicobacter pylori chaperone-like protein CagT plays an essential role in the translocation of CagA into host cells.
Journal of microbiology and biotechnology Oct, 2012 | Pubmed ID: 23075784
Development and characterization of a novel nanoemulsion drug-delivery system for potential application in oral delivery of protein drugs.
International journal of nanomedicine , 2012 | Pubmed ID: 23118537
Structural, enzymatic and biochemical studies on Helicobacter pylori arginase.
The international journal of biochemistry & cell biology May, 2013 | Pubmed ID: 23454280
A novel gastroretentive porous microparticle for anti-Helicobacter pylori therapy: preparation, in vitro and in vivo evaluation.
International journal of pharmaceutics Mar, 2014 | Pubmed ID: 24406672
Efficacy and pharmacological mechanism of pronase-enhanced low-dose antibiotics for Helicobacter pylori eradication.
Antimicrobial agents and chemotherapy Jun, 2014 | Pubmed ID: 24687504
Anti-helicobacter pylori effect of total alkaloids of sophora alopecuroides in vivo.
Chinese medical journal , 2014 | Pubmed ID: 24985588
Immunodominant CD4+ T-cell responses to influenza A virus in healthy individuals focus on matrix 1 and nucleoprotein.
Journal of virology Oct, 2014 | Pubmed ID: 25078703
Outer membrane inflammatory protein A, a new virulence factor involved in the pathogenesis of Helicobacter pylori.
Molecular biology reports Dec, 2014 | Pubmed ID: 25096514
Trastuzumab triggers phagocytic killing of high HER2 cancer cells in vitro and in vivo by interaction with Fcγ receptors on macrophages.
Journal of immunology (Baltimore, Md. : 1950) May, 2015 | Pubmed ID: 25795760
Intranasal immunization with an epitope-based vaccine results in earlier protection, but not better protective efficacy, against Helicobacter pylori compared to subcutaneous immunization.
Immunologic research Jul, 2015 | Pubmed ID: 26044541
Immunization with Heat Shock Protein A and γ-Glutamyl Transpeptidase Induces Reduction on the Helicobacter pylori Colonization in Mice.
PloS one , 2015 | Pubmed ID: 26102080
Efficacy, safety, and immunogenicity of an oral recombinant Helicobacter pylori vaccine in children in China: a randomised, double-blind, placebo-controlled, phase 3 trial.
Lancet (London, England) Oct, 2015 | Pubmed ID: 26142048
Immunodominant epitope-specific Th1 but not Th17 responses mediate protection against Helicobacter pylori infection following UreB vaccination of BALB/c mice.
Scientific reports Oct, 2015 | Pubmed ID: 26434384
Protective Efficacy and Mechanism of Passive Immunization with Polyclonal Antibodies in a Sepsis Model of Staphylococcus aureus Infection.
Scientific reports , 2015 | Pubmed ID: 26490505
Induction of systemic and mucosal immunity against methicillin-resistant Staphylococcus aureus infection by a novel nanoemulsion adjuvant vaccine.
International journal of nanomedicine , 2015 | Pubmed ID: 26664118
Biochemical and functional characterization of the periplasmic domain of the outer membrane protein A from enterohemorrhagic Escherichia coli.
Microbiological research Jan, 2016 | Pubmed ID: 26686619
A novel nitro-dexamethasone inhibits agr system activity and improves therapeutic effects in MRSA sepsis models without antibiotics.
Scientific reports , 2016 | Pubmed ID: 26839286
Protective efficacy of the chimeric Staphylococcus aureus vaccine candidate IC in sepsis and pneumonia models.
Scientific reports , 2016 | Pubmed ID: 26865417
Enhanced efficacy and anti-biofilm activity of novel nanoemulsions against skin burn wound multi-drug resistant MRSA infections.
Nanomedicine : nanotechnology, biology, and medicine Mar, 2016 | Pubmed ID: 26961464
Systematic identification of immunodominant CD4+ T cell responses to HpaA in Helicobacter pylori infected individuals.
Oncotarget 08, 2016 | Pubmed ID: 27509059
Lachnospiraceae shift in the microbial community of mice faecal sample effects on water immersion restraint stress.
AMB Express Dec, 2017 | Pubmed ID: 28417435
Broad-Based CD4 T Cell Responses to Influenza A Virus in a Healthy Individual Who Lacks Typical Immunodominance Hierarchy.
Frontiers in immunology , 2017 | Pubmed ID: 28421076
Protective Efficacy of the Trivalent Pseudomonas aeruginosa Vaccine Candidate PcrV-OprI-Hcp1 in Murine Pneumonia and Burn Models.
Scientific reports 06, 2017 | Pubmed ID: 28638106
Vaccination with a recombinant OprL fragment induces a Th17 response and confers serotype-independent protection against Pseudomonas aeruginosa infection in mice.
Clinical immunology (Orlando, Fla.) 10, 2017 | Pubmed ID: 28970186
The influence of adjuvant on UreB protection against through the diversity of CD4+ T-cell epitope repertoire.
Oncotarget Sep, 2017 | Pubmed ID: 28978104
A novel bivalent fusion vaccine induces broad immunoprotection against Staphylococcus aureus infection in different murine models.
Clinical immunology (Orlando, Fla.) 03, 2018 | Pubmed ID: 29289748
Immunization with Pseudomonas aeruginosa outer membrane vesicles stimulates protective immunity in mice.
Vaccine 02, 2018 | Pubmed ID: 29406241
Immunodominant antigens that induce Th1 and Th17 responses protect mice against infection.
Oncotarget Feb, 2018 | Pubmed ID: 29552292
PA0833 Is an OmpA C-Like Protein That Confers Protection Against Infection.
Frontiers in microbiology , 2018 | Pubmed ID: 29875759
Rational Design and Evaluation of an Artificial K1 Protein Vaccine Candidate Based on the Structure of OmpA.
Frontiers in cellular and infection microbiology , 2018 | Pubmed ID: 29876324
An immunopotentiator, ophiopogonin D, encapsulated in a nanoemulsion as a robust adjuvant to improve vaccine efficacy.
Acta biomaterialia 09, 2018 | Pubmed ID: 30031164
Chitosan-polyvinyl alcohol nanoscale liquid film-forming system facilitates MRSA-infected wound healing by enhancing antibacterial and antibiofilm properties.
International journal of nanomedicine , 2018 | Pubmed ID: 30214202
Development of a safety and efficacy nanoemulsion delivery system encapsulated gambogic acid for acute myeloid leukemia in vitro and in vivo.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Dec, 2018 | Pubmed ID: 30296572
Degranulation of mast cells induced by gastric cancer-derived adrenomedullin prompts gastric cancer progression.
Cell death & disease 10, 2018 | Pubmed ID: 30305610
A lethal pneumonia model of Acinetobacter baumannii: an investigation in immunocompetent mice.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases Apr, 2019 | Pubmed ID: 30583061
The miR-29c-KIAA1199 axis regulates gastric cancer migration by binding with WBP11 and PTP4A3.
Oncogene 04, 2019 | Pubmed ID: 30626935
Epitope-loaded nanoemulsion delivery system with ability of extending antigen release elicits potent Th1 response for intranasal vaccine against Helicobacter pylori.
Journal of nanobiotechnology Jan, 2019 | Pubmed ID: 30660182
Helicobacter pylori-downregulated tumor necrosis factor receptor-associated protein 1 mediates apoptosis of human gastric epithelial cells.
Journal of cellular physiology Feb, 2019 | Pubmed ID: 30710368
Increased intratumoral mast cells foster immune suppression and gastric cancer progression through TNF-α-PD-L1 pathway.
Journal for immunotherapy of cancer 02, 2019 | Pubmed ID: 30808413
Rational Design of a Chimeric Derivative of PcrV as a Subunit Vaccine Against .
Frontiers in immunology , 2019 | Pubmed ID: 31068928
Prophylactic and therapeutic protection of human IgG purified from sera containing anti-exotoxin A titers against pneumonia caused by .
Human vaccines & immunotherapeutics , 2019 | Pubmed ID: 31116632
Rapid and Broad Immune Efficacy of a Recombinant Five-Antigen Vaccine against Infection in Animal Models.
Vaccines Mar, 2020 | Pubmed ID: 32197534
Progress and Prospects on Vaccine Development against SARS-CoV-2.
Vaccines Mar, 2020 | Pubmed ID: 32235387
Determining the immunological characteristics of a novel human monoclonal antibody developed against staphylococcal enterotoxin B.
Human vaccines & immunotherapeutics 07, 2020 | Pubmed ID: 32275466
Toll-like receptors: Triggers of regulated cell death and promising targets for cancer therapy.
Immunology letters 07, 2020 | Pubmed ID: 32311408
Host CD8α and CD103 dendritic cells prime transplant antigen-specific CD8 T cells via cross-dressing.
Immunology and cell biology 08, 2020 | Pubmed ID: 32330333
Expression of ETS1 in gastric epithelial cells positively regulate inflammatory response in Helicobacter pylori-associated gastritis.
Cell death & disease 07, 2020 | Pubmed ID: 32612120
PD-1 does not mark tumor-infiltrating CD8+ T cell dysfunction in human gastric cancer.
Journal for immunotherapy of cancer 08, 2020 | Pubmed ID: 32753468
Complete Genome Sequence of Pseudomonas aeruginosa XN-1, Isolated from the Sputum of a Severe Pneumonia Patient.
Microbiology resource announcements Sep, 2020 | Pubmed ID: 32883796
The efficacy assessment of convalescent plasma therapy for COVID-19 patients: a multi-center case series.
Signal transduction and targeted therapy 10, 2020 | Pubmed ID: 33024082
Genome Sequence of Klebsiella pneumoniae YBQ, a Clinical Strain Isolated from the Sputum of a Patient with Severe Pneumonia.
Microbiology resource announcements Nov, 2020 | Pubmed ID: 33214313
HtrA family proteases of bacterial pathogens: pros and cons for their therapeutic use.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases Apr, 2021 | Pubmed ID: 33359376
Development of a Chimeric Vaccine Against Based on the Th17-Stimulating Epitopes of PcrV and AmpC.
Frontiers in immunology , 2020 | Pubmed ID: 33552056
Development of a chitosan-modified PLGA nanoparticle vaccine for protection against Escherichia coli K1 caused meningitis in mice.
Journal of nanobiotechnology Mar, 2021 | Pubmed ID: 33673858
Flagella hook protein FlgE is a novel vaccine candidate of Pseudomonas aeruginosa identified by a genomic approach.
Vaccine 04, 2021 | Pubmed ID: 33775439
Identification and application of a neutralizing epitope within alpha-hemolysin using human serum antibodies elicited by vaccination.
Molecular immunology 07, 2021 | Pubmed ID: 33873093
A novel self-assembled epitope peptide nanoemulsion vaccine targeting nasal mucosal epithelial cell for reinvigorating CD8 T cell immune activity and inhibiting tumor progression.
International journal of biological macromolecules Jul, 2021 | Pubmed ID: 34052270
Immunodominance of Epitopes and Protective Efficacy of HI Antigen Are Differentially Altered Using Different Adjuvants in a Mouse Model of Bacteremia.
Frontiers in immunology , 2021 | Pubmed ID: 34122448
Vaccination induces rapid protection against bacterial pneumonia via training alveolar macrophage in mice.
eLife 09, 2021 | Pubmed ID: 34544549
High-throughput screening and evaluation of repurposed drugs targeting the SARS-CoV-2 main protease.
Signal transduction and targeted therapy 09, 2021 | Pubmed ID: 34588418
α-Hemolysin-Aided Oligomerization of the Spike Protein RBD Resulted in Improved Immunogenicity and Neutralization Against SARS-CoV-2 Variants.
Frontiers in immunology , 2021 | Pubmed ID: 34630436
HIV-1 Vif suppresses antiviral immunity by targeting STING.
Cellular & molecular immunology 01, 2022 | Pubmed ID: 34811497
Disulfiram Enhances the Activity of Polymyxin B Against by Inhibiting Lipid A Modification.
Infection and drug resistance , 2022 | Pubmed ID: 35115797
Identification and Application of a Panel of Constitutive Promoters for Gene Overexpression in .
Frontiers in microbiology , 2022 | Pubmed ID: 35295303
Evaluation of a recombinant five-antigen Staphylococcus aureus vaccine: The randomized, single-centre phase 1a/1b clinical trials.
Vaccine 05, 2022 | Pubmed ID: 35473663
Immune response effects of diverse vaccine antigen attachment ways based on the self-made nanoemulsion adjuvant in systemic MRSA infection.
RSC advances Mar, 2018 | Pubmed ID: 35540467
Protective effects of a nanoemulsion adjuvant vaccine (2C-Staph/NE) administered intranasally against invasive pneumonia.
RSC advances Mar, 2018 | Pubmed ID: 35540845
Calreticulin enhances gastric cancer metastasis by dimethylating H3K9 in the E-cadherin promoter region mediating by G9a.
Oncogenesis May, 2022 | Pubmed ID: 35641480
A lipophilic chitosan-modified self-nanoemulsifying system influencing cellular membrane metabolism enhances antibacterial and anti-biofilm efficacy for multi-drug resistant Pseudomonas aeruginosa wound infection.
Biomaterials advances Sep, 2022 | Pubmed ID: 36058016
Extracellular fibrinogen-binding protein released by intracellular Staphylococcus aureus suppresses host immunity by targeting TRAF3.
Nature communications Sep, 2022 | Pubmed ID: 36123338
Respiratory mucosal vaccination of peptide-poloxamine-DNA nanoparticles provides complete protection against lethal SARS-CoV-2 challenge.
Biomaterials Nov, 2022 | Pubmed ID: 36436305
Xing Luo1,
Yanan Tong1,
Xiaoqiang Zeng1,
Yan Ye1,
Yun Yang1,
Zhen Song1,
Zelong Zhang1,
Haibo Li1,
Jining Gao2,
Xuhu Mao1,
Hao Zeng1,
Quanming Zou1,
Hongwu Sun1
1Department of Microbiology and Biochemical Pharmacy, National Engineering Research Centre of Immunological Products, College of Pharmacy, Third Military Medical University of Chinese PLA,
2Institute of Combined Injury of PLA, College of Military Preventive Medicine, Third Military Medical University of Chinese PLA
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