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Department of Pathology
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Connective tissue growth factor as a mediator of intraocular fibrosis.
Investigative ophthalmology & visual science Sep, 2008 | Pubmed ID: 18450591
BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration.
The Journal of biological chemistry Apr, 2009 | Pubmed ID: 19158083
Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration.
Vision research Mar, 2010 | Pubmed ID: 19765607
What determines the switch between atrophic and neovascular forms of age related macular degeneration? - the role of BMP4 induced senescence.
Aging Aug, 2009 | Pubmed ID: 20157553
Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival.
Investigative ophthalmology & visual science Mar, 2011 | Pubmed ID: 21087957
Over-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9.
Angiogenesis Jun, 2012 | Pubmed ID: 22392094
A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer.
Ophthalmic research , 2012 | Pubmed ID: 22868580
Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer.
Investigative ophthalmology & visual science Jul, 2013 | Pubmed ID: 23833067
Polarized human embryonic stem cell-derived retinal pigment epithelial cell monolayers have higher resistance to oxidative stress-induced cell death than nonpolarized cultures.
Stem cells translational medicine Jan, 2015 | Pubmed ID: 25411476
TGF-β2 secretion from RPE decreases with polarization and becomes apically oriented.
Cytokine Feb, 2015 | Pubmed ID: 25496702
αB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition.
The American journal of pathology Apr, 2016 | Pubmed ID: 26878210
Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.
Scientific reports 03, 2021 | Pubmed ID: 33737600
Keck School of Medicine of the University of Southern California
Juan Carlos Martinez Camarillo1,2,
Yuntao Hu1,5,
Biju B. Thomas1,2,
Danhong Zhu3,
David R. Hinton2,3,
Debbie Mitra1,2,
Jose Miguel Mora Correa2,
Deepthi S. Rajendran Nair1,2,
Jane Lebkowski4,
Mark S. Humayun1,2
1USC Roski Eye Institute, Keck School of Medicine of the University of Southern California,
2USC Dr. Allen and Charlotte Ginsburg Institute for Biomedical Therapeutics, University of Southern California,
3Department of Pathology, Keck School of Medicine of the University of Southern California,
4, Regenerative Patch Technologies LLC,
5Eye center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University
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