Medical Research Council Centre for Regenerative Medicine,
MRC Centre for Regenerative Medicine
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Activation of NF-kappaB nuclear transcription factor by flow in human endothelial cells.
Biochimica et biophysica acta Sep, 2003 | Pubmed ID: 12972291
Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells.
Stem cells (Dayton, Ohio) , 2004 | Pubmed ID: 14990861
Direct differentiation of human embryonic stem cells to hepatocyte-like cells exhibiting functional activities.
Cloning and stem cells , 2007 | Pubmed ID: 17386014
Progenitor cell characterization and location in the developing human liver.
Stem cells and development Oct, 2007 | Pubmed ID: 17999598
Efficient differentiation of hepatocytes from human embryonic stem cells exhibiting markers recapitulating liver development in vivo.
Stem cells (Dayton, Ohio) Apr, 2008 | Pubmed ID: 18238852
The inhibitory role of stromal cell mesenchyme on human embryonic stem cell hepatocyte differentiation is overcome by Wnt3a treatment.
Cloning and stem cells Sep, 2008 | Pubmed ID: 18479212
Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2008 | Pubmed ID: 18719101
Side population cells in developing human liver are primarily haematopoietic progenitor cells.
Experimental cell research Aug, 2009 | Pubmed ID: 19233167
Progress and future challenges in stem cell-derived liver technologies.
American journal of physiology. Gastrointestinal and liver physiology Aug, 2009 | Pubmed ID: 19520740
Third-degree heart block associated with bupivacaine infusion following total knee arthroplasty. A case report.
The Journal of bone and joint surgery. American volume Sep, 2009 | Pubmed ID: 19724003
Generation of functional human hepatic endoderm from human induced pluripotent stem cells.
Hepatology (Baltimore, Md.) Jan, 2010 | Pubmed ID: 19877180
Three-dimensional culture of human embryonic stem cell derived hepatic endoderm and its role in bioartificial liver construction.
Journal of biomedicine & biotechnology , 2010 | Pubmed ID: 20169088
Portal venous endothelium in developing human liver contains haematopoietic and epithelial progenitor cells.
Experimental cell research May, 2010 | Pubmed ID: 20211168
Hepatic endoderm differentiation from human embryonic stem cells.
Current stem cell research & therapy Sep, 2010 | Pubmed ID: 20214561
Role of stem-cell-derived hepatic endoderm in human drug discovery.
Biochemical Society transactions Aug, 2010 | Pubmed ID: 20658999
Cadaveric hepatocytes repopulate diseased livers: life after death.
Gastroenterology Sep, 2010 | Pubmed ID: 20659459
Pluripotent stem cell derived hepatocyte like cells and their potential in toxicity screening.
Toxicology Dec, 2010 | Pubmed ID: 20674645
Post-translational modification by SUMO.
Toxicology Dec, 2010 | Pubmed ID: 20674646
The comparison between conditioned media and serum-free media in human embryonic stem cell culture and differentiation.
Cellular reprogramming Apr, 2010 | Pubmed ID: 20677928
Persistence of functional hepatocyte-like cells in immune-compromised mice.
Liver international : official journal of the International Association for the Study of the Liver Feb, 2011 | Pubmed ID: 21143581
Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism.
Stem cell research Mar, 2011 | Pubmed ID: 21277274
The complexities of engineering human stem cell-derived therapeutics.
Journal of biomedicine & biotechnology , 2010 | Pubmed ID: 21490704
Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.
Cell research Sep, 2011 | Pubmed ID: 21747414
Balta Lucendo-Villarin1,
Hassan Rashidi1,2,
Sharmin Alhaque1,3,
Lena Fischer1,4,
Jose Meseguer-Ripolles1,
Yu Wang1,
Cliona O'Farrelly4,
Michael Themis3,
David C. Hay1
1MRC Centre for Regenerative Medicine, University of Edinburgh,
2UCL Great Ormond Street Institute of Child Health, University College London,
3Division of Biosciences, Department of Life Sciences, College of Health and Life Sciences, Brunel University London,
4School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin
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