Jason Mercer

Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells.

Investigation of structural and functional motifs within the vaccinia virus A14 phosphoprotein, an essential component of the virion membrane.

Regulation of CXC chemokine receptor 4-mediated migration by the Tec family tyrosine kinase ITK.

Natural killer T cells: rapid responders controlling immunity and disease.

Genetic and cell biological characterization of the vaccinia virus A30 and G7 phosphoproteins.

Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1.

Emerging perspectives in store-operated Ca2+ entry: roles of Orai, Stim and TRP.

Subversion of CtBP1-controlled macropinocytosis by human adenovirus serotype 3.

Vaccinia virus uses macropinocytosis and apoptotic mimicry to enter host cells.

Virus entry by macropinocytosis.

Chemico-genetic identification of drebrin as a regulator of calcium responses.

Virus entry by endocytosis.

Vaccinia virus strains use distinct forms of macropinocytosis for host-cell entry.

Activation and regulation of store-operated calcium entry.

Apoptotic mimicry: phosphatidylserine-mediated macropinocytosis of vaccinia virus.

Viral apoptotic mimicry party: P.S. Bring your own Gas6.

Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture.

Poxvirus host cell entry.

Corannulene and its penta-tert-butyl derivative co-crystallize 1:1 with pristine C60-fullerene.

Single-cell analysis of population context advances RNAi screening at multiple levels.

Cooperative vaccinia infection demonstrated at the single-cell level using FluidFM.

Gulping rather than sipping: macropinocytosis as a way of virus entry.

Vaccinia virus egress: actin OUT with clathrin.

Direct identification of ligand-receptor interactions on living cells and tissues.

RNAi screening reveals proteasome- and Cullin3-dependent stages in vaccinia virus infection.

Biogenesis of the vaccinia virus membrane: genetic and ultrastructural analysis of the contributions of the A14 and A17 proteins.

A facile protocol for the immobilisation of vesicles, virus particles, bacteria, and yeast cells.

Virus entry by endocytosis.

Virus interactions with endocytic pathways in macrophages and dendritic cells.

[Cellular protein disposal system assists poxvirus genome uncoating].

Single-virus fusion experiments reveal proton influx into vaccinia virions and hemifusion lag times.

Vaccinia virus entry is followed by core activation and proteasome-mediated release of the immunomodulatory effector VH1 from lateral bodies.

Tracking viral genomes in host cells at single-molecule resolution.

siRNA screen of early poxvirus genes identifies the AAA+ ATPase D5 as the virus genome-uncoating factor.

Next generation approaches to study virus entry and infection.

Lipid interactions during virus entry and infection.

Simultaneous analysis of large-scale RNAi screens for pathogen entry.

DNA virus uncoating.

Vaccinia Virus Infection Requires Maturation of Macropinosomes.

Viral apoptotic mimicry.

Cloak and Dagger: Alternative Immune Evasion and Modulation Strategies of Poxviruses.

Infectio: a Generic Framework for Computational Simulation of Virus Transmission between Cells.

VirusMapper: open-source nanoscale mapping of viral architecture through super-resolution microscopy.

VEGF induces signalling and angiogenesis by directing VEGFR2 internalisation through macropinocytosis.