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Department of Chemistry and Biochemistry,
Molecular Biology Institute,
Jonsson Comprehensive Cancer Center
Jorge Z. Torres has not added Biography.
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Local chromatin structure at the ribosomal DNA causes replication fork pausing and genome instability in the absence of the S. cerevisiae DNA helicase Rrm3p.
Genes & development Mar, 2004 | Pubmed ID: 15037547
Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activities.
Molecular and cellular biology Apr, 2004 | Pubmed ID: 15060144
The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes.
Genes & development Nov, 2006 | Pubmed ID: 17114583
The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis.
Developmental cell Jul, 2007 | Pubmed ID: 17609108
High-throughput generation of tagged stable cell lines for proteomic analysis.
Proteomics May, 2009 | Pubmed ID: 19405035
A specific form of phospho protein phosphatase 2 regulates anaphase-promoting complex/cyclosome association with spindle poles.
Molecular biology of the cell Mar, 2010 | Pubmed ID: 20089842
The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly.
Cell Dec, 2011 | Pubmed ID: 22153075
STARD9/Kif16a is a novel mitotic kinesin and antimitotic target.
Bioarchitecture Jan, 2012 | Pubmed ID: 22754624
An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity.
Cancer research May, 2013 | Pubmed ID: 23440422
Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors.
PloS one , 2014 | Pubmed ID: 25036740
p16 Protein and gigaxonin are associated with the ubiquitination of NFκB in cisplatin-induced senescence of cancer cells.
The Journal of biological chemistry Dec, 2014 | Pubmed ID: 25331947
A unique insertion in STARD9's motor domain regulates its stability.
Molecular biology of the cell Feb, 2015 | Pubmed ID: 25501367
Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens.
PLoS computational biology Mar, 2015 | Pubmed ID: 25826798
Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis.
Cell cycle (Georgetown, Tex.) , 2015 | Pubmed ID: 25830415
A LCMT1-PME-1 methylation equilibrium controls mitotic spindle size.
Cell cycle (Georgetown, Tex.) , 2015 | Pubmed ID: 25839665
Structures of potent anticancer compounds bound to tubulin.
Protein science : a publication of the Protein Society Jul, 2015 | Pubmed ID: 25970265
The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division.
Cell reports Jan, 2016 | Pubmed ID: 26748699
Proteomic Analysis of the Mammalian Katanin Family of Microtubule-severing Enzymes Defines Katanin p80 subunit B-like 1 (KATNBL1) as a Regulator of Mammalian Katanin Microtubule-severing.
Molecular & cellular proteomics : MCP May, 2016 | Pubmed ID: 26929214
Cystatin E/M Suppresses Tumor Cell Growth through Cytoplasmic Retention of NF-κB.
Molecular and cellular biology Jun, 2016 | Pubmed ID: 27090639
3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping.
ACS chemical biology Aug, 2016 | Pubmed ID: 27285961
Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division.
The Journal of biological chemistry Aug, 2016 | Pubmed ID: 27378817
University of California, Los Angeles
Michelle Bradley1,
Ivan Ramirez1,
Keith Cheung1,
Ankur A. Gholkar1,
Jorge Z. Torres1,2,3
1Department of Chemistry and Biochemistry, University of California, Los Angeles,
2Molecular Biology Institute, University of California, Los Angeles,
3Jonsson Comprehensive Cancer Center, University of California, Los Angeles
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