Jyoti S. Choudhary

Proteomic analysis of in vivo phosphorylated synaptic proteins.

Robust enrichment of phosphorylated species in complex mixtures by sequential protein and peptide metal-affinity chromatography and analysis by tandem mass spectrometry.

Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome.

Analysis of protein phosphorylation on a proteome-scale.

Phosphoproteomic analysis of the mouse brain cytosol reveals a predominance of protein phosphorylation in regions of intrinsic sequence disorder.

Evolutionary expansion and anatomical specialization of synapse proteome complexity.

Mapping multiprotein complexes by affinity purification and mass spectrometry.

Neurotransmitters drive combinatorial multistate postsynaptic density networks.

Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins.

Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency.

Characterization of the proteome, diseases and evolution of the human postsynaptic density.

Shotgun proteomics aids discovery of novel protein-coding genes, alternative splicing, and "resurrected" pseudogenes in the mouse genome.

Citrobacter rodentium is an unstable pathogen showing evidence of significant genomic flux.

Quantitative proteomics reveals the basis for the biochemical specificity of the cell-cycle machinery.

APC15 drives the turnover of MCC-CDC20 to make the spindle assembly checkpoint responsive to kinetochore attachment.

Coordinating cell cycle progression via cyclin specificity.

Assignment of protein interactions from affinity purification/mass spectrometry data.

Enhanced peptide identification by electron transfer dissociation using an improved Mascot Percolator.

A Plasmodium calcium-dependent protein kinase controls zygote development and transmission by translationally activating repressed mRNAs.

Analysis of protein palmitoylation reveals a pervasive role in Plasmodium development and pathogenesis.

Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins.

A polygenic burden of rare disruptive mutations in schizophrenia.

The OMSSAPercolator: an automated tool to validate OMSSA results.

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism.

Confident and sensitive phosphoproteomics using combinations of collision induced dissociation and electron transfer dissociation.

A new method to determine in vivo interactomes reveals binding of the Legionella pneumophila effector PieE to multiple rab GTPases.

Human post-mortem synapse proteome integrity screening for proteomic studies of postsynaptic complexes.

Palmitoylation and palmitoyl-transferases in Plasmodium parasites.

Cyclic diGMP regulates production of sortase substrates of Clostridium difficile and their surface exposure through ZmpI protease-mediated cleavage.

Quantitative proteomic analysis of Shigella flexneri and Shigella sonnei Generalized Modules for Membrane Antigens (GMMA) reveals highly pure preparations.

Study of Plasmodium falciparum DHHC palmitoyl transferases identifies a role for PfDHHC9 in gametocytogenesis.

Interferon-driven alterations of the host's amino acid metabolism in the pathogenesis of typhoid fever.

Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow.

DecoyPyrat: Fast Non-redundant Hybrid Decoy Sequence Generation for Large Scale Proteomics.

OpenMS: a flexible open-source software platform for mass spectrometry data analysis.

Flexible Data Analysis Pipeline for High-Confidence Proteogenomics.

Evolution of complexity in the zebrafish synapse proteome.

Myst2/Kat7 histone acetyltransferase interaction proteomics reveals tumour-suppressor Niam as a novel binding partner in embryonic stem cells.

Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells.

Sub-minute Phosphoregulation of Cell Cycle Systems during Plasmodium Gamete Formation.

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.