Kiyosumi Shibata

Prolonged survival and decreased invasive activity attributable to dipeptidyl peptidase IV overexpression in ovarian carcinoma.

Preoperative findings in non-gynecologic carcinomas metastasizing to the ovaries.

Dipeptidyl peptidase IV expression in endometrial endometrioid adenocarcinoma and its inverse correlation with tumor grade.

Neutral endopeptidase/CD10 expression in the stroma of epithelial ovarian carcinoma.

Expression of CD26/dipeptidyl peptidase IV in endometrial adenocarcinoma and its negative correlation with tumor grade.

Adhesion potency to mesothelial cells by overexpression of dipeptidyl peptidase IV.

Survival time and invasive activity due to dipeptidyl peptidase IV overexpression in ovarian carcinoma.

Possible role of placental leucine aminopeptidase in the antiproliferative effect of oxytocin in human endometrial adenocarcinoma.

Dipeptidyl peptidase IV overexpression induces up-regulation of E-cadherin and tissue inhibitors of matrix metalloproteinases, resulting in decreased invasive potential in ovarian carcinoma cells.

Increased adhesion potency of ovarian carcinoma cells to mesothelial cells by overexpression of dipeptidyl peptidase IV.

Long-term prognosis of stage I ovarian carcinoma. Prognostic importance of intraoperative rupture.

Enhancement of aminopeptidase A expression during angiotensin II-induced choriocarcinoma cell proliferation through AT1 receptor involving protein kinase C- and mitogen-activated protein kinase-dependent signaling pathway.

Cushing's syndrome due to ovarian serous adenocarcinoma secreting multiple endocrine substances: a case report and immunohistochemical analysis.

Expression of adipocyte-derived leucine aminopeptidase in endometrial cancer. Association with tumor grade and CA-125.

Usefulness of preoperative chemoradiation in locally advanced cervical carcinoma.

Expression of placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase in human normal and malignant invasive trophoblastic cells.

Adipocyte-derived leucine aminopeptidase suppresses angiogenesis in human endometrial carcinoma via renin-angiotensin system.

Oxytocin inhibits the progression of human ovarian carcinoma cells in vitro and in vivo.

Regulation of aminopeptidase A expression in cervical carcinoma: role of tumor-stromal interaction and vascular endothelial growth factor.

Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cells by overexpression of AP-2alpha.

Stromal cell-derived factor-1alpha-induced cell proliferation and its possible regulation by CD26/dipeptidyl peptidase IV in endometrial adenocarcinoma.

Activation of invasiveness of cervical carcinoma cells by angiotensin II.

Expression of placental leucine aminopeptidase is associated with a poor outcome in endometrial endometrioid adenocarcinoma.

Regulatory role of membrane-bound peptidases in the progression of gynecologic malignancies.

Placental leucine aminopeptidase (P-LAP) expression is associated with chemosensitivity in human endometrial carcinoma.

Possible involvement of adipocyte-derived leucine aminopeptidase via angiotensin II in endometrial carcinoma.

Neutral endopeptidase 24.11/CD10 suppresses progressive potential in ovarian carcinoma in vitro and in vivo.

Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal dissemination.

Gene regulation and physiological function of placental leucine aminopeptidase/oxytocinase during pregnancy.

Placental leucine aminopeptidase (P-LAP) and glucose transporter 4 (GLUT4) expression in benign, borderline, and malignant ovarian epithelia.

Dipeptidyl peptidase IV in tumor progression.

Anti-progressive effect of neutral endopeptidase 24.11 (NEP/CD10) on cervical carcinoma in vitro and in vivo.

A novel role for placental leucine aminopeptidase (P-LAP) as a determinant of chemoresistance in endometrial carcinoma cells.

Manipulating the angiotensin system--new approaches to the treatment of solid tumours.

Clinical characteristics and prognosis of mucinous tumors of the ovary.

Advances in treatment of epithelial ovarian cancer.

Long-term follow-up and prognostic factor analysis in clear cell adenocarcinoma of the ovary.

Endometrioid adenocarcinoma arising from endometriosis during 2 years of estrogen replacement therapy after total hysterectomy and bilateral salpingo-oophorectomy.

Involvement of DPPIV/CD26 in epithelial morphology and suppressed invasive ability in ovarian carcinoma cells.

P-LAP/IRAP-induced cell proliferation and glucose uptake in endometrial carcinoma cells via insulin receptor signaling.

Involvement of aminopeptidase N in enhanced chemosensitivity to paclitaxel in ovarian carcinoma in vitro and in vivo.

Essential role of placental leucine aminopeptidase in gynecologic malignancy.

Possible involvement of TWIST in enhanced peritoneal metastasis of epithelial ovarian carcinoma.

Uterine smooth muscle cells increase invasive ability of endometrial carcinoma cells through tumor-stromal interaction.

Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells.

Establishment of a new cell line of endometrioid carcinoma of the ovary and its chemosensitivity.

Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells.

Twist expression predicts poor clinical outcome of patients with clear cell carcinoma of the ovary.

Possible involvement of SDF-1alpha/CXCR4-DPPIV axis in TGF-beta1-induced enhancement of migratory potential in human peritoneal mesothelial cells.

Involvement of SDF-1alpha/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma.

Irradiation-induced epithelial-mesenchymal transition (EMT) related to invasive potential in endometrial carcinoma cells.

Angiotensin II mimics the hypoxic effect on regulating trophoblast proliferation and differentiation in human placental explant cultures.

Gene directed enzyme prodrug therapy for ovarian cancer: could GDEPT become a promising treatment against ovarian cancer?

Survival benefit of taxane plus platinum in recurrent ovarian cancer with non-clear cell, non-mucinous histology.

Taxol resistance among the different histological subtypes of ovarian cancer may be associated with the expression of class III beta-tubulin.

Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer.

Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival.

Is there any possibility of fertility-sparing surgery in patients with clear-cell carcinoma of the ovary?

Establishment and characterization of an ovarian yolk sac tumor cell line reveals possible involvement of Nkx2.5 in tumor development.

Feasibility and effectiveness of postoperative adjuvant concurrent chemoradiation therapy in Japanese patients with high-risk early-stage cancer of the uterine cervix.

Long-term outcome and prognostic factors for yolk sac tumor of the ovary.

N-acetylglucosaminyltransferase V regulates extravillous trophoblast invasion through glycosylation of alpha5beta1 integrin.

Overexpression of indoleamine 2,3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model.

Enhanced cytotoxicity with a novel system combining the paclitaxel-2'-ethylcarbonate prodrug and an HSV amplicon with an attenuated replication-competent virus, HF10 as a helper virus.

Tocilizumab inhibits interleukin-6-mediated matrix metalloproteinase-2 and -9 secretions from human amnion cells in preterm premature rupture of membranes.

Expression of Ret finger protein correlates with outcomes in endometrial cancer.

Role of the immunosuppressive enzyme indoleamine 2,3-dioxygenase in the progression of ovarian carcinoma.

High expression of N-acetylglucosaminyltransferase V in mucinous tumors of the ovary.

Gene silencing of glypican-3 in clear cell carcinoma of the ovary renders it more sensitive to the apoptotic agent paclitaxel in vitro and in vivo.

The expression of dipeptidyl peptidase IV (DPPIV/CD26) is associated with enhanced chemosensitivity to paclitaxel in epithelial ovarian carcinoma cells.

Thyroid transcription factor 1 expression in ovarian carcinomas is an independent prognostic factor.

Intra-amniotic infection increases amniotic lamellar body count before 34 weeks of gestation.

Indoleamine 2,3-dioxygenase expression predicts impaired survival of invasive cervical cancer patients treated with radical hysterectomy.

Growth-suppressing function of glypican-3 (GPC3) via insulin like growth factor II (IGF-II) signaling pathway in ovarian clear cell carcinoma cells.

Identification and characterization of cancer stem cells in ovarian yolk sac tumors.

Glypican-3 expression predicts poor clinical outcome of patients with early-stage clear cell carcinoma of the ovary.

Establishment of cisplatin-resistant ovarian yolk sac tumor cells and investigation of the mechanism of cisplatin resistance using this cell line.

Spectrin αII and βII tetramers contribute to platinum anticancer drug resistance in ovarian serous adenocarcinoma.

Role of the renin-angiotensin system in gynecologic cancers.

Mismatched human leukocyte antigen class II-restricted CD8⁺ cytotoxic T cells may mediate selective graft-versus-leukemia effects following allogeneic hematopoietic cell transplantation.

Fertility-sparing surgery in young women with mucinous adenocarcinoma of the ovary.

Glypican-3 could be an effective target for immunotherapy combined with chemotherapy against ovarian clear cell carcinoma.

Prognostic factors in stage IA-IIA cervical cancer patients treated surgically: does the waiting time to the operation affect survival?

Strong antibody reaction against glycosphingolipids injected in liposome-embedded forms in beta3GN-T5 knockout mice.

Survival impact of capsule rupture in stage I clear cell carcinoma of the ovary in comparison with other histological types.

Fertility-sparing surgery in patients with clear-cell carcinoma of the ovary: is it possible?

Functional interaction between peritoneal mesothelial cells and stem cells of ovarian yolk sac tumor (SC-OYST) in peritoneal dissemination.

Survival impact of adjuvant paclitaxel and carboplatin for early-stage ovarian clear-cell carcinoma with complete surgical staging.

Expression of CXCR4 indicates poor prognosis in patients with clear cell carcinoma of the ovary.

Long-term clinical outcome of patients with recurrent epithelial ovarian carcinoma: is it the same for each histological type?

Diagnostic utility of CD117, CD133, SALL4, OCT4, TCL1 and glypican-3 in malignant germ cell tumors of the ovary.

Is there any association between retroperitoneal lymphadenectomy and survival benefit in advanced stage epithelial ovarian carcinoma patients?

Postrecurrent oncologic outcome of patients with ovarian clear cell carcinoma.

Adjuvant chemotherapy for stage i ovarian clear cell carcinoma: is it necessary for stage IA?

Expression of Twist enhances risk of poor oncologic outcome in patients with stage Ib to II cervical carcinoma with lymphovascular space involvement.

[Fertility-sparing surgery in epithelial ovarian cancer].

ALX1 induces snail expression to promote epithelial-to-mesenchymal transition and invasion of ovarian cancer cells.

Anti-Müllerian hormone as a marker of ovarian reserve in patients with ovarian malignancies who have undergone fertility-preserving surgery and chemotherapy.

Expression of RET finger protein predicts chemoresistance in epithelial ovarian cancer.

Extremely poor postrecurrence oncological outcome for patients with recurrent mucinous ovarian cancer.

The expression and characterization of endoglin in uterine leiomyosarcoma.

An HLA-modified ovarian cancer cell line induced CTL responses specific to an epitope derived from claudin-1 presented by HLA-A*24:02 molecules.

Significant clinical response of progressive recurrent ovarian clear cell carcinoma to glypican-3-derived peptide vaccine therapy: two case reports.

A recurrence-predicting prognostic factor for patients with ovarian clear-cell adenocarcinoma at reproductive age.

Growing teratoma syndrome of the ovary showing three patterns of metastasis: a case report.

Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinoma via TRAIL-induced apoptotic pathway regulation.

Recurrence-predicting prognostic factors for patients with early-stage epithelial ovarian cancer undergoing fertility-sparing surgery: a multi-institutional study.

Suppression of REV7 enhances cisplatin sensitivity in ovarian clear cell carcinoma cells.

Is there any association between where patients spend the end of life and survival after anticancer treatment for gynecologic malignancy?

B7-H4 overexpression correlates with a poor prognosis for cervical cancer patients.

PLAGL2 regulates actin cytoskeletal architecture and cell migration.

Possible association between stem-like hallmark and radioresistance in human cervical carcinoma cells.

Clinicopathologic features of epithelial ovarian carcinoma in younger vs. older patients: analysis in Japanese women.

Opioid needs of terminally ill patients with gynecologic malignancies.

Expression of the miR200 family of microRNAs in mesothelial cells suppresses the dissemination of ovarian cancer cells.

GPC3 expression in mouse ovarian cancer induces GPC3‑specific T cell-mediated immune response through M1 macrophages and suppresses tumor growth.

Oncologic outcome after recurrence in patients with stage I epithelial ovarian cancer: are clear-cell and mucinous histological types a different entities?

Paclitaxel and carboplatin in patients with completely or optimally resected carcinosarcoma of the uterus: a phase II trial by the Japanese Uterine Sarcoma Group and the Tohoku Gynecologic Cancer Unit.

HOXB13 and ALX4 induce SLUG expression for the promotion of EMT and cell invasion in ovarian cancer cells.

The prognostic impact of pulmonary metastasectomy in recurrent gynecologic cancers: a retrospective single-institution study.

Radiotherapy for persistent malignant transformation from mature cystic teratoma of the ovary.

PRIMA-1MET induces apoptosis through accumulation of intracellular reactive oxygen species irrespective of p53 status and chemo-sensitivity in epithelial ovarian cancer cells.

Comparison of prognoses according to non-positive and positive spectrin αII expression detected immunohistochemically in epithelial ovarian carcinoma: a retrospective study.

Contrast-enhanced ultrasonography using Sonazoid(®) is useful for diagnosis of malignant ovarian tumors: comparison with Doppler ultrasound.

Feasibility and benefit of concurrent chemoradiotherapy for elderly patients with uterine cervical cancer.

Oncologic and obstetric outcomes of early stage cervical cancer with abdominal radical trachelectomy: Single-institution experience.