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Schmid College of Science
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Increased relaxant action of forskolin and isoproterenol against muscarinic agonist-induced contractions in smooth muscle from M2 receptor knockout mice.
The Journal of pharmacology and experimental therapeutics Apr, 2003 | Pubmed ID: 12649358
Comparison of the pharmacological antagonism of M2 and M3 muscarinic receptors expressed in isolation and in combination.
Biochemical pharmacology Apr, 2003 | Pubmed ID: 12694864
Muscarinic agonist-mediated heterologous desensitization in isolated ileum requires activation of both muscarinic M2 and M3 receptors.
The Journal of pharmacology and experimental therapeutics Jan, 2004 | Pubmed ID: 14563784
Comparison of the antimuscarinic action of p-fluorohexahydrosiladifenidol in ileal and tracheal smooth muscle.
The Journal of pharmacology and experimental therapeutics Feb, 2005 | Pubmed ID: 15456838
The M2 muscarinic receptor mediates contraction through indirect mechanisms in mouse urinary bladder.
The Journal of pharmacology and experimental therapeutics Apr, 2005 | Pubmed ID: 15608083
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
The Journal of pharmacology and experimental therapeutics Jun, 2007 | Pubmed ID: 17392404
Two-state models and the analysis of the allosteric effect of gallamine at the M2 muscarinic receptor.
The Journal of pharmacology and experimental therapeutics Jun, 2008 | Pubmed ID: 18305010
Selectivity of agonists for the active state of M1 to M4 muscarinic receptor subtypes.
The Journal of pharmacology and experimental therapeutics Jan, 2009 | Pubmed ID: 18824613
The guinea pig ileum lacks the direct, high-potency, M(2)-muscarinic, contractile mechanism characteristic of the mouse ileum.
Naunyn-Schmiedeberg's archives of pharmacology Oct, 2009 | Pubmed ID: 19582435
Analysis of agonism and inverse agonism in functional assays with constitutive activity: estimation of orthosteric ligand affinity constants for active and inactive receptor states.
The Journal of pharmacology and experimental therapeutics Aug, 2011 | Pubmed ID: 21576379
Analysis of functional responses at G protein-coupled receptors: estimation of relative affinity constants for the inactive receptor state.
The Journal of pharmacology and experimental therapeutics Aug, 2011 | Pubmed ID: 21576380
Muscarinic agonists and antagonists: effects on gastrointestinal function.
Handbook of experimental pharmacology , 2012 | Pubmed ID: 22222706
Chapman University
Frederick J. Ehlert1,
Hinako Suga2,
Michael T. Griffin3
1Department of Pharmacology, University of California, Irvine,
2Department of Pharmacology, University of California,
3Schmid College of Science, Chapman University
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