Ronit Sagi-Eisenberg

Down-regulating protein kinase C alpha: functional cooperation between the proteasome and the endocytic system.

Synaptotagmin II negatively regulates Ca2+-triggered exocytosis of lysosomes in mast cells.

Gi-mediated activation of the p42/p44 mitogen-activated protein kinases by receptor mimetic basic secretagogues is abrogated by inhibitors of endocytosis.

Suppression of Synaptotagmin II restrains phorbolester-induced downregulation of protein kinase Calpha by diverting the kinase from a degradative pathway to the recycling endocytic compartment.

Synaptotagmin II negatively regulates MHC class II presentation by mast cells.

The molecular mechanisms of allergic diseases: immunoglobulin E dependent and independent signaling pathways converge in eliciting the release of arachidonic acid metabolites.

Synaptotagmin III is a critical factor for the formation of the perinuclear endocytic recycling compartment and determination of secretory granules size.

Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules.

Neuronal calcium sensor-1 and phosphatidylinositol 4-kinase beta regulate IgE receptor-triggered exocytosis in cultured mast cells.

O-glycosylation is essential for intracellular targeting of synaptotagmins I and II in non-neuronal specialized secretory cells.

Classical protein kinase C(s) regulates targeting of synaptotagmin IX to the endocytic recycling compartment.

Neuronal calcium sensor-1 and phosphatidylinositol 4-kinase beta stimulate extracellular signal-regulated kinase 1/2 signaling by accelerating recycling through the endocytic recycling compartment.

Synaptotagmin (Syt) IX is an essential determinant for protein sorting to secretory granules in mast cells.

The mast cell: where endocytosis and regulated exocytosis meet.

Molecular impacts of rapamycin-based drug combinations: combining rapamycin with gemcitabine or imatinib mesylate (Gleevec) in a human leiomyosarcoma model.

Inhibition of basic secretagogue-induced signaling in mast cells by cell permeable G alpha i-derived peptides.

Targeting mTOR in HIV-Negative Classic Kaposi's Sarcoma.

Targeting the mammalian target of rapamycin in myxoid chondrosarcoma.

Activation of mast cells by trimeric G protein Gi3; coupling to the A3 adenosine receptor directly and upon T cell contact.

Protein trafficking in immune cells.

Combining an EGFR directed tyrosine kinase inhibitor with autophagy-inducing drugs: a beneficial strategy to combat non-small cell lung cancer.

Mast cell adenosine receptors function: a focus on the a3 adenosine receptor and inflammation.

Decoding the regulation of mast cell exocytosis by networks of Rab GTPases.

Clinical activity of mTOR inhibition in combination with cyclophosphamide in the treatment of recurrent unresectable chondrosarcomas.

The extra-cellular signal regulated kinases ERK1 and ERK2 segregate displaying distinct spatiotemporal characteristics in activated mast cells.

Rab5 is a novel regulator of mast cell secretory granules: impact on size, cargo, and exocytosis.

Characterization of mast cell secretory granules and their cell biology.

Down-regulation of the A3 adenosine receptor in human mast cells upregulates mediators of angiogenesis and remodeling.

Rab12 Regulates Retrograde Transport of Mast Cell Secretory Granules by Interacting with the RILP-Dynein Complex.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Different activation signals induce distinct mast cell degranulation strategies.

Mast cells are directly activated by contact with cancer cells by a mechanism involving autocrine formation of adenosine and autocrine/paracrine signaling of the adenosine A3 receptor.

Rab5 is critical for SNAP23 regulated granule-granule fusion during compound exocytosis.

RBL cells as models for in vitro studies of mast cells and basophils.