Torben Heick Jensen

Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation.

Early formation of mRNP: license for export or quality control?

Localization of nuclear retained mRNAs in Saccharomyces cerevisiae.

Modulation of transcription affects mRNP quality.

Dramatically improved RNA in situ hybridization signals using LNA-modified probes.

The role of the Brr5/Ysh1 C-terminal domain and its homolog Syc1 in mRNA 3'-end processing in Saccharomyces cerevisiae.

A novel plasmid-based microarray screen identifies suppressors of rrp6Delta in Saccharomyces cerevisiae.

Dissecting mechanisms of nuclear mRNA surveillance in THO/sub2 complex mutants.

Nuclear mRNA surveillance in THO/sub2 mutants is triggered by inefficient polyadenylation.

The T body, a new cytoplasmic RNA granule in Saccharomyces cerevisiae.

Exonucleolysis is required for nuclear mRNA quality control in yeast THO mutants.

RNA exosome depletion reveals transcription upstream of active human promoters.

Assembly of export-competent mRNP: it's all about being connected.

Assembly of an export-competent mRNP is needed for efficient release of the 3'-end processing complex after polyadenylation.

The yeast 5'-3' exonuclease Rat1p functions during transcription elongation by RNA polymerase II.

The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.

Crosstalk between mRNA 3' end processing and transcription initiation.

Translation by remote control.

A pause to splice.

The eukaryotic RNA exosome: same scaffold but variable catalytic subunits.

T-body formation precedes virus-like particle maturation in S. cerevisiae.

PROMoter uPstream Transcripts share characteristics with mRNAs and are produced upstream of all three major types of mammalian promoters.

RNA exosome. Preface.

Interaction profiling identifies the human nuclear exosome targeting complex.

Implication of Ccr4-Not complex function in mRNA quality control in Saccharomyces cerevisiae.

Nuclear quality control of RNA polymerase II transcripts.

Saccharomyces cerevisiae Ngl3p is an active 3'-5' exonuclease with a specificity towards poly-A RNA reminiscent of cellular deadenylases.

Improved methodology for the affinity isolation of human protein complexes expressed at near endogenous levels.

Rrp6p controls mRNA poly(A) tail length and its decoration with poly(A) binding proteins.

Nuclear retention prevents premature cytoplasmic appearance of mRNA.

Transcription-associated quality control of mRNP.

Promoter-proximal polyadenylation sites reduce transcription activity.

MRN1 implicates chromatin remodeling complexes and architectural factors in mRNA maturation.

Making ends meet: coordination between RNA 3'-end processing and transcription initiation.

Exonuclease hDIS3L2 specifies an exosome-independent 3'-5' degradation pathway of human cytoplasmic mRNA.

Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality.

Mutational analysis of the yeast RNA helicase Sub2p reveals conserved domains required for growth, mRNA export, and genomic stability.

Dealing with pervasive transcription.

The human cap-binding complex is functionally connected to the nuclear RNA exosome.

Rat1p maintains RNA polymerase II CTD phosphorylation balance.

SnapShot: nuclear RNAPII transcript modification.

Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes.

The human nuclear exosome targeting complex is loaded onto newly synthesized RNA to direct early ribonucleolysis.

Rapid, optimized interactomic screening.

The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production.

Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes.

Human Gene Promoters Are Intrinsically Bidirectional.

Relationships between PROMPT and gene expression.

Biochemistry and Function of RNA Exosomes.

Purification and analysis of endogenous human RNA exosome complexes.

Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters.

A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation.

Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.

Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.

Lariat capping as a tool to manipulate the 5' end of individual yeast mRNA species in vivo.

Nuclear Decay Factors Crack Up mRNA.

Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate.

Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage.

Characterising -regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues.

Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production.

ARS2 is a general suppressor of pervasive transcription.

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

Transcription start site analysis reveals widespread divergent transcription in D. melanogaster and core promoter-encoded enhancer activities.

Controlling nuclear RNA levels.

The RNA Exosome Adaptor ZFC3H1 Functionally Competes with Nuclear Export Activity to Retain Target Transcripts.

Diminished nuclear RNA decay upon infection upregulates antibacterial noncoding RNAs.

A Nuclear Export Block Triggers the Decay of Newly Synthesized Polyadenylated RNA.

Simultaneous Measurement of Transcriptional and Post-transcriptional Parameters by 3' End RNA-Seq.

The RNA exosome contributes to gene expression regulation during stem cell differentiation.

Box C/D snoRNP Autoregulation by a cis-Acting snoRNA in the NOP56 Pre-mRNA.

The multitasking polyA tail: nuclear RNA maturation, degradation and export.

Escaping nuclear decay: the significance of mRNA export for gene expression.

Preparation of RNA 3' End Sequencing Libraries of Total and 4-thiouracil Labeled RNA for Simultaneous Measurement of Transcription, RNA Synthesis and Decay in .

The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs.

The long noncoding RNA is seemingly dispensable for normal tissue homeostasis and cancer cell growth.

Nuclear sorting of RNA.

A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2.

Global Identification of Human Exosome Substrates Using RNA Interference and RNA Sequencing.

The Nuclear RNA Exosome and Its Cofactors.

The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay.

A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome.