Wim J. H. Hagen

Determination of protein structure at 8.5Å resolution using cryo-electron tomography and sub-tomogram averaging.

SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion.

Cryo-electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly.

Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution.

Seeing tobacco mosaic virus through direct electron detectors.

An organized co-assembly of clathrin adaptors is essential for endocytosis.

The selective autophagy receptor p62 forms a flexible filamentous helical scaffold.

The Structure of Immature Virus-Like Rous Sarcoma Virus Gag Particles Reveals a Structural Role for the p10 Domain in Assembly.

Molecular structures of unbound and transcribing RNA polymerase III.

Molecular architecture of the inner ring scaffold of the human nuclear pore complex.

Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging.

An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation.

Molecular Structures of Transcribing RNA Polymerase I.

The structure and flexibility of conical HIV-1 capsids determined within intact virions.

Structure of the hexagonal surface layer on Caulobacter crescentus cells.

9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.

Molecular mechanism of promoter opening by RNA polymerase III.

Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake.

Benchmarking tomographic acquisition schemes for high-resolution structural biology.

Structural basis for RNA polymerase III transcription repression by Maf1.

TEM bright field imaging of thick specimens: nodes in Thon ring patterns.

In-cell architecture of an actively transcribing-translating expressome.

Combining high throughput and high quality for cryo-electron microscopy data collection.

In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges.

Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress.

Defocus-dependent Thon-ring fading.