David Sulzer

Regulation of quantal size by presynaptic mechanisms.

Dale's principle and glutamate corelease from ventral midbrain dopamine neurons.

Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles.

The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease.

Transgenic superoxide dismutase overproducer: murine.

Stimulation-dependent regulation of the pH, volume and quantal size of bovine and rodent secretory vesicles.

Altered dopamine release and uptake kinetics in mice lacking D2 receptors.

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis.

The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate.

Dopamine transport currents are promoted from curiosity to physiology.

Intraneuronal dopamine-quinone synthesis: a review.

D3 dopamine autoreceptors do not activate G-protein-gated inwardly rectifying potassium channel currents in substantia nigra dopamine neurons.

Intracellular patch electrochemistry: regulation of cytosolic catecholamines in chromaffin cells.

Presynaptic regulation of dopaminergic neurotransmission.

Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics.

Real-time decoding of dopamine concentration changes in the caudate-putamen during tonic and phasic firing.

Glutamate spillover in the striatum depresses dopaminergic transmission by activating group I metabotropic glutamate receptors.

Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses.

Dopamine neurons release transmitter via a flickering fusion pore.

Regulation of the development of mesencephalic dopaminergic systems by the selective expression of glial cell line-derived neurotrophic factor in their targets.

Frequency-dependent modulation of dopamine release by nicotine.

Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminals.

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy.

The neuromelanin of human substantia nigra: physiological and pathogenic aspects.

Neurodegeneration and neuroprotection in Parkinson disease.

Antidepressants and the monoamine masquerade.

Mechanisms of neurotransmitter release by amphetamines: a review.

SNAREs can promote complete fusion and hemifusion as alternative outcomes.

Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons.

Analysis of exocytotic events recorded by amperometry.

Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice.

Sorting of vesicular monoamine transporter 2 to the regulated secretory pathway confers the somatodendritic exocytosis of monoamines.

Alpha-synuclein overexpression increases cytosolic catecholamine concentration.

A glial cell line-derived neurotrophic factor (GDNF):tetanus toxin fragment C protein conjugate improves delivery of GDNF to spinal cord motor neurons in mice.

Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis.

Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease.

Parkinson's disease: return of an old prime suspect.

Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy.

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.

PKC theta activity maintains normal quantal size in chromaffin cells.

Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways.

Methamphetamine inhibits antigen processing, presentation, and phagocytosis.

Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease.

Repeated exposure to methamphetamine causes long-lasting presynaptic corticostriatal depression that is renormalized with drug readministration.

Secretory vesicle rebound hyperacidification and increased quantal size resulting from prolonged methamphetamine exposure.

Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein.

Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons.

Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals.

Presynaptic regulation of dopamine transmission in schizophrenia.

Glutamate controls growth rate and branching of dopaminergic axons.

Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease.

Clues to how alpha-synuclein damages neurons in Parkinson's disease.

Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo.

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.

Development of pH-responsive fluorescent false neurotransmitters.

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

How addictive drugs disrupt presynaptic dopamine neurotransmission.

Multiple personalities in the ventral tegmental area.

Imaging presynaptic exocytosis in corticostriatal slices.

4-Component relativistic magnetically induced current density using London atomic orbitals.

Constitutive upregulation of chaperone-mediated autophagy in Huntington's disease.

Regulation of presynaptic neurotransmission by macroautophagy.

Neuronal vulnerability, pathogenesis, and Parkinson's disease.

Calcium currents regulate dopamine autoreceptors.

Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits.

Voluntary adolescent drinking enhances excitation by low levels of alcohol in a subset of dopaminergic neurons in the ventral tegmental area.

Dopamine's Effects on Corticostriatal Synapses during Reward-Based Behaviors.