Michael A. Tangrea

Solution structure of the pro-hormone convertase 1 pro-domain from Mus musculus.

Post-analysis follow-up and validation of microarray experiments.

Layered expression scanning: multiplex analysis of RNA and protein gels.

Molecular profiling of cancer.

Expression microdissection: operator-independent retrieval of cells for molecular profiling.

Histomathematical analysis of clinical specimens: challenges and progress.

Novel proteomic approaches for tissue analysis.

Molecular alterations in primary prostate cancer after androgen ablation therapy.

Layered peptide arrays: high-throughput antibody screening of clinical samples.

Gene promoter methylation in prostate tumor-associated stromal cells.

Tumor-associated endothelial cells display GSTP1 and RARbeta2 promoter methylation in human prostate cancer.

Layered expression scanning: multiplex molecular analysis of diverse life science platforms.

Layered peptide arrays: a diverse technique for antibody screening of clinical samples.

Layered peptide array for multiplex immunohistochemistry.

Global expression analysis of prostate cancer-associated stroma and epithelia.

Combining agents that target the tumor microenvironment improves the efficacy of anticancer therapy.

Current molecular diagnostics of breast cancer and the potential incorporation of microRNA.

High throughput screening of normal and neoplastic tissue samples.

Increased matrix metalloproteinase activation in esophageal squamous cell carcinoma.

Layered electrophoretic transfer - A method for pre-analytic processing of histological sections.

Expression microdissection adapted to commercial laser dissection instruments.

Effect of immunohistochemistry on molecular analysis of tissue samples: implications for microdissection technologies.

Quantifying mRNA levels across tissue sections with 2D-RT-qPCR.

SIVQ-aided laser capture microdissection: A tool for high-throughput expression profiling.

Differential vitamin D 24-hydroxylase/CYP24A1 gene promoter methylation in endothelium from benign and malignant human prostate.

Immunoguided microdissection techniques.

MicroRNA analysis of microdissected normal squamous esophageal epithelium and tumor cells.

A dynamic magnetic shift method to increase nanoparticle concentration in cancer metastases: a feasibility study using simulations on autopsy specimens.

Identification of unique expression signatures and therapeutic targets in esophageal squamous cell carcinoma.

Three-dimensional mRNA measurements reveal minimal regional heterogeneity in esophageal squamous cell carcinoma.

Optimal molecular profiling of tissue and tissue components: defining the best processing and microdissection methods for biomedical applications.

Proteomic analysis of frozen tissue samples using laser capture microdissection.

Measuring collective cell movement and extracellular matrix interactions using magnetic resonance imaging.

Validation of esophageal squamous cell carcinoma candidate genes from high-throughput transcriptomic studies.