Deepak Kaushal

Reduced immunopathology and mortality despite tissue persistence in a Mycobacterium tuberculosis mutant lacking alternative sigma factor, SigH.

Attenuation of late-stage disease in mice infected by the Mycobacterium tuberculosis mutant lacking the SigF alternate sigma factor and identification of SigF-dependent genes by microarray analysis.

Microarray analysis of pneumococcal gene expression during invasive disease.

Revising the role of the pneumococcal vex-vncRS locus in vancomycin tolerance.

Vancomycin stress response in a sensitive and a tolerant strain of Streptococcus pneumoniae.

Identification of a Candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal disease.

Evaluation of IFN-gamma effects on apoptosis and gene expression in neuroblastoma--preclinical studies.

Platelet-activating factor receptor and innate immunity: uptake of gram-positive bacterial cell wall into host cells and cell-specific pathophysiology.

General nature of the STAT3-activated anti-inflammatory response.

A novel approach for the analysis of T-cell reconstitution by using a T-cell receptor beta-based oligonucleotide microarray in hematopoietic stem cell transplantation.

An overview of Spotfire for gene-expression studies.

An overview of Spotfire for gene-expression studies.

Loading and preparing data for analysis in spotfire.

Analyzing and visualizing expression data with Spotfire.

Long-term in vitro expansion alters the biology of adult mesenchymal stem cells.

Closing the phenotypic gap between transformed neuronal cell lines in culture and untransformed neurons.

Interaction of the Lyme disease spirochete Borrelia burgdorferi with brain parenchyma elicits inflammatory mediators from glial cells as well as glial and neuronal apoptosis.

The antibiotics doxycycline and minocycline inhibit the inflammatory responses to the Lyme disease spirochete Borrelia burgdorferi.

Functional genomics reveals extended roles of the Mycobacterium tuberculosis stress response factor sigmaH.

Microglia are mediators of Borrelia burgdorferi-induced apoptosis in SH-SY5Y neuronal cells.

A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine.

Genetic requirements for the survival of tubercle bacilli in primates.

Mycobacterium tuberculosis MT2816 encodes a key stress-response regulator.

Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas.

Improved xenobiotic metabolism and reduced susceptibility to cancer in gluten-sensitive macaques upon introduction of a gluten-free diet.

Reactivation of latent tuberculosis in rhesus macaques by coinfection with simian immunodeficiency virus.

Interleukin-10 alters effector functions of multiple genes induced by Borrelia burgdorferi in macrophages to regulate Lyme disease inflammation.

Aerosolized gentamicin reduces the burden of tuberculosis in a murine model.

MicroRNA profiling reveals age-dependent differential expression of nuclear factor κB and mitogen-activated protein kinase in adipose and bone marrow-derived human mesenchymal stem cells.

The stress-response factor SigH modulates the interaction between Mycobacterium tuberculosis and host phagocytes.

The Mycobacterium tuberculosis stress response factor SigH is required for bacterial burden as well as immunopathology in primate lungs.

Focused examination of the intestinal lamina propria yields greater molecular insight into mechanisms underlying SIV induced immune dysfunction.

Increased expression of P-glycoprotein and doxorubicin chemoresistance of metastatic breast cancer is regulated by miR-298.

Eicosanoids, prostaglandins, and the progression of tuberculosis.

Transient acidification and subsequent proinflammatory cytokine stimulation of astrocytes induce distinct activation phenotypes.

Granuloma correlates of protection against tuberculosis and mechanisms of immune modulation by Mycobacterium tuberculosis.

CXCR5⁺ T helper cells mediate protective immunity against tuberculosis.

How well do you know your monkeys?

Role of interleukin 6 in innate immunity to Mycobacterium tuberculosis infection.

Focused examination of the intestinal epithelium reveals transcriptional signatures consistent with disturbances in enterocyte maturation and differentiation during the course of SIV infection.

Expression levels of 10 candidate genes in lung tissue of vaccinated and TB-infected cynomolgus macaques.

S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis.

Faithful Experimental Models of Human Mycobacterium Tuberculosis Infection.

The Mycobacterium tuberculosis Rv2745c Plays an Important Role in Responding to Redox Stress.

Role of TNF in the Altered Interaction of Dormant Mycobacterium tuberculosis with Host Macrophages.

Unexpected Role for IL-17 in Protective Immunity against Hypervirulent Mycobacterium tuberculosis HN878 Infection.