Joy Lincoln

Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos.

Hearts and bones: shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development.

Extracellular matrix remodeling and organization in developing and diseased aortic valves.

BMP and FGF regulatory pathways control cell lineage diversification of heart valve precursor cells.

ColVa1 and ColXIa1 are required for myocardial morphogenesis and heart valve development.

Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development.

Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo.

Temporal and spatial expression of collagens during murine atrioventricular heart valve development and maintenance.

Reduced sox9 function promotes heart valve calcification phenotypes in vivo.

Differential changes in TGF-β/BMP signaling pathway in the right ventricular myocardium of newborns with hypoplastic left heart syndrome.

Molecular and developmental mechanisms of congenital heart valve disease.

Is aviation a good model to study human errors in health care?

Mmp15 is a direct target of Snai1 during endothelial to mesenchymal transformation and endocardial cushion development.

FGF23 induces left ventricular hypertrophy.

Sox9 transcriptionally represses Spp1 to prevent matrix mineralization in maturing heart valves and chondrocytes.

Myocardial alternative RNA splicing and gene expression profiling in early stage hypoplastic left heart syndrome.

Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse.

Heart valve development, maintenance, and disease: the role of endothelial cells.

Collagen XIV is important for growth and structural integrity of the myocardium.

Increased dietary intake of vitamin A promotes aortic valve calcification in vivo.

Snai1 is important for avian epicardial cell transformation and motility.

Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.

Tgfβ-Smad and MAPK signaling mediate scleraxis and proteoglycan expression in heart valves.

Genetics of valvular heart disease.

RNA-seq analysis to identify novel roles of scleraxis during embryonic mouse heart valve remodeling.

Etiology of valvular heart disease.