Department of Biological Chemistry
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Epidermal growth factor receptor activation under oxidative stress fails to promote c-Cbl mediated down-regulation.
The Journal of biological chemistry Aug, 2002 | Pubmed ID: 12063263
Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells.
American journal of physiology. Lung cellular and molecular physiology Jun, 2003 | Pubmed ID: 12576296
c-Cbl-mediated ubiquitinylation is required for epidermal growth factor receptor exit from the early endosomes.
The Journal of biological chemistry Aug, 2004 | Pubmed ID: 15210722
NF-kappaB signaling: flipping the switch with polyubiquitin chains.
Current biology : CB Oct, 2004 | Pubmed ID: 15498483
Life and death decisions: ceramide generation and EGF receptor trafficking are modulated by oxidative stress.
Antioxidants & redox signaling Jan-Feb, 2005 | Pubmed ID: 15650401
Tumor necrosis factor-{alpha} decreases Akt protein levels in 3T3-L1 adipocytes via the caspase-dependent ubiquitination of Akt.
Endocrinology Jun, 2005 | Pubmed ID: 15746249
Epidermal growth factor receptor exposed to oxidative stress undergoes Src- and caveolin-1-dependent perinuclear trafficking.
The Journal of biological chemistry May, 2006 | Pubmed ID: 16407214
Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways.
The EMBO journal Feb, 2006 | Pubmed ID: 16437165
An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2006 | Pubmed ID: 16847254
Autoregulation of an E2 enzyme by ubiquitin-chain assembly on its catalytic residue.
Nature cell biology Apr, 2007 | Pubmed ID: 17310239
Diversity of degradation signals in the ubiquitin-proteasome system.
Nature reviews. Molecular cell biology Sep, 2008 | Pubmed ID: 18698327
EGF receptor exposed to oxidative stress acquires abnormal phosphorylation and aberrant activated conformation that impairs canonical dimerization.
PloS one , 2011 | Pubmed ID: 21853092
Exposure of bipartite hydrophobic signal triggers nuclear quality control of Ndc10 at the endoplasmic reticulum/nuclear envelope.
Molecular biology of the cell Dec, 2011 | Pubmed ID: 21998200
Endoplasmic reticulum stress induces a caspase-dependent N-terminal cleavage of RBX1 protein in B cells.
The Journal of biological chemistry Sep, 2012 | Pubmed ID: 22822056
Placing a disrupted degradation motif at the C terminus of proteasome substrates attenuates degradation without impairing ubiquitylation.
The Journal of biological chemistry May, 2013 | Pubmed ID: 23519465
Ubiquitin conjugation triggers misfolded protein sequestration into quality control foci when Hsp70 chaperone levels are limiting.
Molecular biology of the cell Jul, 2013 | Pubmed ID: 23637465
Chaperoning Proteins for Destruction: Diverse Roles of Hsp70 Chaperones and their Co-Chaperones in Targeting Misfolded Proteins to the Proteasome.
Biomolecules , 2014 | Pubmed ID: 25036888
The DNA2 nuclease/helicase is an estrogen-dependent gene mutated in breast and ovarian cancers.
Oncotarget Oct, 2014 | Pubmed ID: 25238049
Flow Cytometric Quantification and Characterization of Intracellular Protein Aggregates in Yeast.
Prion May, 2014 | Pubmed ID: 25247293
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