Claire M. Payne

Epidermal growth factor reduces the development of necrotizing enterocolitis in a neonatal rat model.

Role of mitochondrial complexes I and II, reactive oxygen species and arachidonic acid metabolism in deoxycholate-induced apoptosis.

Detoxification of the polyamine analogue N1-ethyl-N11-[(cycloheptyl)methy]-4,8-diazaundecane (CHENSpm) by polyamine oxidase.

Up-regulation of IL-18 and IL-12 in the ileum of neonatal rats with necrotizing enterocolitis.

DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis.

Patchy field defects of apoptosis resistance and dedifferentiation in flat mucosa of colon resections from colon cancer patients.

Long-term effects of ovarian follicular depletion in rats by 4-vinylcyclohexene diepoxide.

Imexon activates an intrinsic apoptosis pathway in RPMI8226 myeloma cells.

Molecular and cellular characterization of imexon-resistant RPMI8226/I myeloma cells.

Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate.

Nicotine increases oxidative stress, activates NF-kappaB and GRP78, induces apoptosis and sensitizes cells to genotoxic/xenobiotic stresses by a multiple stress inducer, deoxycholate: relevance to colon carcinogenesis.

Perils of immunohistochemistry: variability in staining specificity of commercially available COX-2 antibodies on human colon tissue.

Deoxycholate, an endogenous tumor promoter and DNA damaging agent, modulates BRCA-1 expression in apoptosis-sensitive epithelial cells: loss of BRCA-1 expression in colonic adenocarcinomas.

A proteomic study of resistance to deoxycholate-induced apoptosis.

alpha-Tocopheryl succinate sensitizes established tumors to vaccination with nonmatured dendritic cells.

Increased expression and secretion of interleukin-6 in patients with Barrett's esophagus.

Epidermal growth factor reduces intestinal apoptosis in an experimental model of necrotizing enterocolitis.

Apoptosis resistance in Barrett's esophagus: ex vivo bioassay of live stressed tissues.

Assessment of apoptosis by immunohistochemical markers compared to cellular morphology in ex vivo-stressed colonic mucosa.

Crypt-restricted loss and decreased protein expression of cytochrome C oxidase subunit I as potential hypothesis-driven biomarkers of colon cancer risk.

Docetaxel induces cell death through mitotic catastrophe in human breast cancer cells.

The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis.

Identification of S-nitrosylated proteins after chronic exposure of colon epithelial cells to deoxycholate.

Role of polyamines in arginine-dependent colon carcinogenesis in Apc(Min) (/+) mice.

Reduced Pms2 expression in non-neoplastic flat mucosa from patients with colon cancer correlates with reduced apoptosis competence.

Pathogenesis of diarrhea in the adult: diagnostic challenges and life-threatening conditions.

Abnormal expression of biomarkers in incompletely ablated Barrett's esophagus.

Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus.

Deoxycholate-induced colitis is markedly attenuated in Nos2 knockout mice in association with modulation of gene expression profiles.

MRI-measured water mobility increases in response to chemotherapy via multiple cell-death mechanisms.

Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to barrett's esophagus.

A novel dietary-related model of esophagitis and Barrett's esophagus, a premalignant lesion.

Field defects in progression to gastrointestinal tract cancers.

Expression of bile acid transporting proteins in Barrett's esophagus and esophageal adenocarcinoma.

Bile acids as endogenous etiologic agents in gastrointestinal cancer.

Deoxycholate, an endogenous cytotoxin/genotoxin, induces the autophagic stress-survival pathway: implications for colon carcinogenesis.

Exposure of mouse colon to dietary bile acid supplement induces sessile adenomas.

Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis.

Carcinogenicity of deoxycholate, a secondary bile acid.

Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis.

Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.

Maspin is a deoxycholate-inducible, anti-apoptotic stress-response protein differentially expressed during colon carcinogenesis.