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BRAF activation initiates but does not maintain invasive prostate adenocarcinoma.
PloS one , 2008 | Pubmed ID: 19079609
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis.
Cell stem cell Nov, 2009 | Pubmed ID: 19896444
Retinoic acid inhibits telomerase activity and downregulates expression but does not affect splicing of hTERT: correlation with cell growth rate inhibition in an in vitro cervical carcinogenesis/multidrug-resistance model.
Experimental cell research Jan, 2002 | Pubmed ID: 11777343
The alkaloid sanguinarine is effective against multidrug resistance in human cervical cells via bimodal cell death.
Biochemical pharmacology Apr, 2002 | Pubmed ID: 11996882
Genomic organization of the human mi-er1 gene and characterization of alternatively spliced isoforms: regulated use of a facultative intron determines subcellular localization.
Gene Jul, 2002 | Pubmed ID: 12242014
Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain.
Molecular and cellular biology Jan, 2003 | Pubmed ID: 12482978
The SANT domain of human MI-ER1 interacts with Sp1 to interfere with GC box recognition and repress transcription from its own promoter.
The Journal of biological chemistry Jul, 2004 | Pubmed ID: 15117948
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.
Cell Jan, 2007 | Pubmed ID: 17254969
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
Nature Oct, 2008 | Pubmed ID: 18948956
FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis.
Cancer cell Nov, 2010 | Pubmed ID: 21075312
SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression.
Nature Feb, 2011 | Pubmed ID: 21289624
Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.
Cell Feb, 2012 | Pubmed ID: 22341440
Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases.
Cell Mar, 2012 | Pubmed ID: 22341455
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