Christopher Heeschen

Statins have biphasic effects on angiogenesis.

Withdrawal of statins increases event rates in patients with acute coronary syndromes.

A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors.

Withdrawal of statins in patients with acute coronary syndromes.

Prognostic significance of angiogenic growth factor serum levels in patients with acute coronary syndromes.

Nicotine strongly activates dendritic cell-mediated adaptive immunity: potential role for progression of atherosclerotic lesions.

Nicotine promotes arteriogenesis.

Soluble CD40 ligand in acute coronary syndromes.

Serum level of the antiinflammatory cytokine interleukin-10 is an important prognostic determinant in patients with acute coronary syndromes.

Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization.

Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes.

Second hand smoke stimulates tumor angiogenesis and growth.

Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells.

Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells.

Prognostic value of placental growth factor in patients with acute chest pain.

p21Cip1 levels differentially regulate turnover of mature endothelial cells, endothelial progenitor cells, and in vivo neovascularization.

Quantitative bedside testing of troponin T: is it equal to laboratory testing? The Cardiac Reader Troponin T (CARE T) study.

111In-labeled CD34+ hematopoietic progenitor cells in a rat myocardial infarction model.

Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease.

Inflammatory markers and coronary artery disease.

Interleukin-10 serum levels and systemic endothelial vasoreactivity in patients with coronary artery disease.

The role of NOS3 in stem cell mobilization.

The pro-apoptotic serum activity is an independent mortality predictor of patients with heart failure.

N-terminal pro-B-type natriuretic peptide levels for dynamic risk stratification of patients with acute coronary syndromes.

Role of beta2-integrins for homing and neovascularization capacity of endothelial progenitor cells.

Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis.

Cathepsin L is required for endothelial progenitor cell-induced neovascularization.

Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells.

Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization.

Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells.

Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease.

Biochemical monitoring of mTOR inhibitor-based immunosuppression following kidney transplantation: a novel approach for tailored immunosuppressive therapy.

Biomarkers in acute coronary syndromes and their role in diabetic patients.

Elevated placental growth factor levels are associated with adverse outcomes at four-year follow-up in patients with acute coronary syndromes.

Influence of sample type and storage conditions on soluble CD40 ligand assessment.

Differential effects of short-term lipid lowering with ezetimibe and statins on endothelial function in patients with CAD: clinical evidence for 'pleiotropic' functions of statin therapy.

Effects of granulocyte colony simulating factor on functional activities of endothelial progenitor cells in patients with chronic ischemic heart disease.

Ex vivo pretreatment of bone marrow mononuclear cells with endothelial NO synthase enhancer AVE9488 enhances their functional activity for cell therapy.

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia.

Endothelial progenitor cells participate in nicotine-mediated angiogenesis.

The immunosuppressant FTY720 inhibits tumor angiogenesis via the sphingosine 1-phosphate receptor 1.

Nonbone marrow-derived circulating progenitor cells contribute to postnatal neovascularization following tissue ischemia.

Influence of sample type on soluble CD40 ligand assessment in patients with acute coronary syndromes.

Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure.

Nonbone marrow-derived endothelial progenitor cells: what is their exact location?

Genetically engineered stem cells for therapeutic gene delivery.

Quantitation of myocardial borderzone using reconstructive 3-D echocardiography after chronic infarction in rats: incremental value of low-dose dobutamine.

Metastatic cancer stem cells: a new target for anti-cancer therapy?

Concentration of bone marrow total nucleated cells by a point-of-care device provides a high yield and preserves their functional activity.

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer.

More good reasons for adherence to statin therapy during acute coronary syndromes.

The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal stem cell niche.

Prostaglandin E positively modulates endothelial progenitor cell homeostasis: an advanced treatment modality for autologous cell therapy.

cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesis.

Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer.

Add some fat to vascular progenitor cell therapy.

Pancreatic cancer stem cells--insights and perspectives.

Cancer stem cells as new therapeutic target to prevent tumour progression and metastasis.

Cancer stem cells in solid tumors.

Pancreatic cancer stem cells - update and future perspectives.

Combination of injectable multiple growth factor-releasing scaffolds and cell therapy as an advanced modality to enhance tissue neovascularization.

Adiponectin pretreatment counteracts the detrimental effect of a diabetic environment on endothelial progenitors.

Inhibition of ataxia telangiectasia- and Rad3-related function abrogates the in vitro and in vivo tumorigenicity of human colon cancer cells through depletion of the CD133(+) tumor-initiating cell fraction.

Pancreatic cancer stem cells: new insights and perspectives.

Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.

EpCAM/CD3-Bispecific T-cell engaging antibody MT110 eliminates primary human pancreatic cancer stem cells.

Stem cells as the root of pancreatic ductal adenocarcinoma.

Vascular incorporation of endothelial colony-forming cells is essential for functional recovery of murine ischemic tissue following cell therapy.

Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness.

Immuno-targeting of pancreatic cancer stem cells: A new therapeutic strategy against a devastating disease?

Metastatic cancer stem cells--quo vadis?

Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1).

Stem cells & pancreatic cancer.

Standing out from the crowd: cancer stem cells in hepatocellular carcinoma.

Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts.

Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells.

Chloroquine targets pancreatic cancer stem cells via inhibition of CXCR4 and hedgehog signaling.

Nicotine Promotes Initiation and Progression of KRAS-Induced Pancreatic Cancer via Gata6-Dependent Dedifferentiation of Acinar Cells in Mice.

Intracellular autofluorescence: a biomarker for epithelial cancer stem cells.

K-RasV14I recapitulates Noonan syndrome in mice.

ISG15 is a critical microenvironmental factor for pancreatic cancer stem cells.

Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms.

Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment.

The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells.