Gijsbert M. Grotenbreg

Synthesis and biological evaluation of novel turn-modified gramicidin S analogues.

An unusual reverse turn structure adopted by a furanoid sugar amino acid incorporated in gramicidin S.

A practical synthesis of gramicidin s and sugar amino Acid containing analogues.

Synthesis and application of carbohydrate-derived morpholine amino acids.

Synthesis and biological evaluation of gramicidin S dimers.

A microengraving method for rapid selection of single cells producing antigen-specific antibodies.

Beta-turn modified gramicidin S analogues containing arylated sugar amino acids display antimicrobial and hemolytic activity comparable to the natural product.

Double-stranded helical twisted beta-sheet channels in crystals of gramicidin S grown in the presence of trifluoroacetic and hydrochloric acids.

Empty class II major histocompatibility complex created by peptide photolysis establishes the role of DM in peptide association.

Sortagging: a versatile method for protein labeling.

Discovery of CD8+ T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramers.

Parasite stage-specific recognition of endogenous Toxoplasma gondii-derived CD8+ T cell epitopes.

The CD8 T-cell response against murine gammaherpesvirus 68 is directed toward a broad repertoire of epitopes from both early and late antigens.

Lipid modification of proteins through sortase-catalyzed transpeptidation.

Site-specific N- and C-terminal labeling of a single polypeptide using sortases of different specificity.

Structural and biological evaluation of some loloatin C analogues.

Ring-extended derivatives of gramicidin S with furanoid sugar amino acids in the turn region have enhanced antimicrobial activity.

Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells.

Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT.

Oligoproline helices as structurally defined scaffolds for oligomeric G protein-coupled receptor ligands.

Synthesis and evaluation of strand and turn modified ring-extended gramicidin S derivatives.

Sources of diversity in T cell epitope discovery.

Stability screening of arrays of major histocompatibility complexes on combinatorially encoded flow cytometry beads.

Engineering T cells specific for a dominant severe acute respiratory syndrome coronavirus CD8 T cell epitope.