Ick Chan kwon

Super pH-sensitive multifunctional polymeric micelle for tumor pH(e) specific TAT exposure and multidrug resistance.

Antitumor effect of a transducible fusogenic peptide releasing multiple proapoptotic peptides by caspase-3.

Identification of a peptide ligand recognizing dysfunctional endothelial cells for targeting atherosclerosis.

Stability and bioactivity of nanocomplex of TNF-related apoptosis-inducing ligand.

Dark quenched matrix metalloproteinase fluorogenic probe for imaging osteoarthritis development in vivo.

Real-time imaging of NF-AT nucleocytoplasmic shuttling with a photoswitchable fluorescence protein in live cells.

A new homing peptide toward tumor vasculature shows tissue specificity.

Activatable imaging probes with amplified fluorescent signals.

Dynamic microPET technique: an in vivo GPS navigation tool.

Engineered polymers for advanced drug delivery.

Phage display selection of peptides that home to atherosclerotic plaques: IL-4 receptor as a candidate target in atherosclerosis.

Injectable in situ-forming pH/thermo-sensitive hydrogel for bone tissue engineering.

Tumor specificity and therapeutic efficacy of photosensitizer-encapsulated glycol chitosan-based nanoparticles in tumor-bearing mice.

Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles.

A near-infrared fluorescence-based optical thermosensor.

Lipid-based emulsion system as non-viral gene carriers.

Hydrotropic oligomer-conjugated glycol chitosan as a carrier of paclitaxel: synthesis, characterization, and in vivo biodistribution.

Anionic amino acid-derived cationic lipid for siRNA delivery.

Hyaluronic acid complexed to biodegradable poly L-arginine for targeted delivery of siRNAs.

Human extracellular matrix powders for tissue engineering.

Self-assembled hyaluronic acid nanoparticles for active tumor targeting.

The hydrogel template method for fabrication of homogeneous nano/microparticles.

Stability and cellular uptake of polymerized siRNA (poly-siRNA)/polyethylenimine (PEI) complexes for efficient gene silencing.

Polymeric nanoparticle-based activatable near-infrared nanosensor for protease determination in vivo.

Targeted delivery of low molecular drugs using chitosan and its derivatives.

Heparin-coated gold nanoparticles for liver-specific CT imaging.

Nanobubbles from gas-generating polymeric nanoparticles: ultrasound imaging of living subjects.

Current status of nanoparticle-based imaging agents for early diagnosis of cancer and atherosclerosis.

Protease imaging of human atheromata captures molecular information of atherosclerosis, complementing anatomic imaging.

Tumor-targeting peptide conjugated pH-responsive micelles as a potential drug carrier for cancer therapy.

The effect of surface functionalization of PLGA nanoparticles by heparin- or chitosan-conjugated Pluronic on tumor targeting.

Conjugated polymer nanoparticles for biomedical in vivo imaging.

Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice.

Tumoral acidic pH-responsive MPEG-poly(beta-amino ester) polymeric micelles for cancer targeting therapy.

Tumor targeting chitosan nanoparticles for dual-modality optical/MR cancer imaging.

Cellular uptake pathway and drug release characteristics of drug-encapsulated glycol chitosan nanoparticles in live cells.

The incorporation of GALA peptide into a protein cage for an acid-inducible molecular switch.

Development of bimolecular fluorescence complementation using Dronpa for visualization of protein-protein interactions in cells.

Pegylated poly-l-arginine derivatives of chitosan for effective delivery of siRNA.

Tumor-homing multifunctional nanoparticles for cancer theragnosis: Simultaneous diagnosis, drug delivery, and therapeutic monitoring.

Hydrotropic hyaluronic acid conjugates: Synthesis, characterization, and implications as a carrier of paclitaxel.

A mesoporous silica nanoparticle with charge-convertible pore walls for efficient intracellular protein delivery.

Improved antitumor activity and tumor targeting of NH(2)-terminal-specific PEGylated tumor necrosis factor-related apoptosis-inducing ligand.

Dab1 binds to Fe65 and diminishes the effect of Fe65 or LRP1 on APP processing.

Reduced dose-limiting toxicity of intraperitoneal mitoxantrone chemotherapy using cardiolipin-based anionic liposomes.

"One-step" detection of matrix metalloproteinase activity using a fluorogenic peptide probe-immobilized diagnostic kit.

In-vivo tumor targeting of pluronic-based nano-carriers.

In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles.

Tumor targeting efficiency of bare nanoparticles does not mean the efficacy of loaded anticancer drugs: importance of radionuclide imaging for optimization of highly selective tumor targeting polymeric nanoparticles with or without drug.

Paclitaxel-loaded Pluronic nanoparticles formed by a temperature-induced phase transition for cancer therapy.

Ionic complex systems based on hyaluronic acid and PEGylated TNF-related apoptosis-inducing ligand for treatment of rheumatoid arthritis.

Caspase sensitive gold nanoparticle for apoptosis imaging in live cells.

Optimization of matrix metalloproteinase fluorogenic probes for osteoarthritis imaging.

Trilysinoyl oleylamide-based cationic liposomes for systemic co-delivery of siRNA and an anticancer drug.

pH-Sensitive nanoflash for tumoral acidic pH imaging in live animals.

Matrix metalloproteinase sensitive gold nanorod for simultaneous bioimaging and photothermal therapy of cancer.

Heavy-atomic construction of photosensitizer nanoparticles for enhanced photodynamic therapy of cancer.

PEGylation of hyaluronic acid nanoparticles improves tumor targetability in vivo.

Real time, high resolution video imaging of apoptosis in single cells with a polymeric nanoprobe.

Near-infrared fluorescence imaging using a protease-specific probe for the detection of colon tumors.

Exercise attenuates matrix metalloproteinase activity in preexisting atherosclerotic plaque.

Tumor-homing photosensitizer-conjugated glycol chitosan nanoparticles for synchronous photodynamic imaging and therapy based on cellular on/off system.

Comparative study of photosensitizer loaded and conjugated glycol chitosan nanoparticles for cancer therapy.

Application of near-infrared fluorescence imaging using a polymeric nanoparticle-based probe for the diagnosis and therapeutic monitoring of colon cancer.

Glycol chitosan/heparin immobilized iron oxide nanoparticles with a tumor-targeting characteristic for magnetic resonance imaging.

Real-time and non-invasive optical imaging of tumor-targeting glycol chitosan nanoparticles in various tumor models.

Photosensitizer-conjugated human serum albumin nanoparticles for effective photodynamic therapy.

A monitoring method for Atg4 activation in living cells using peptide-conjugated polymeric nanoparticles.

Small heat shock protein as a multifunctional scaffold: integrated tumor targeting and caspase imaging within a single cage.

Self-assembled nanoparticles based on hyaluronic acid-ceramide (HA-CE) and Pluronic® for tumor-targeted delivery of docetaxel.

In situ dose amplification by apoptosis-targeted drug delivery.

Molecular targeting of atherosclerotic plaques by a stabilin-2-specific peptide ligand.

Multi-core vesicle nanoparticles based on vesicle fusion for delivery of chemotherapic drugs.

Development of MRI/NIRF 'activatable' multimodal imaging probe based on iron oxide nanoparticles.

In vivo targeted delivery of nanoparticles for theranosis.

Nanogel with endosome-escaping function.

Bioreducible block copolymers based on poly(ethylene glycol) and poly(γ-benzyl L-glutamate) for intracellular delivery of camptothecin.

Facilitated intracellular delivery of peptide-guided nanoparticles in tumor tissues.

Tumor-targeting gold particles for dual computed tomography/optical cancer imaging.

Smart nanocarrier based on PEGylated hyaluronic acid for cancer therapy.

Direct thrombus imaging as a means to control the variability of mouse embolic infarct models: the role of optical molecular imaging.

Gas-generating polymeric microspheres for long-term and continuous in vivo ultrasound imaging.

Polyethylene glycol-conjugated hyaluronic acid-ceramide self-assembled nanoparticles for targeted delivery of doxorubicin.

Early diagnosis of arthritis in mice with collagen-induced arthritis, using a fluorogenic matrix metalloproteinase 3-specific polymeric probe.

Tumor accumulation and antitumor efficacy of docetaxel-loaded core-shell-corona micelles with shell-specific redox-responsive cross-links.

Enhancement of the targeting capabilities of the Paclitaxel-loaded pluronic nanoparticles with a glycol chitosan/heparin composite.

Multifunctional nanoparticles for multimodal imaging and theragnosis.

The movement of self-assembled amphiphilic polymeric nanoparticles in the vitreous and retina after intravitreal injection.

Tumor-targeting hyaluronic acid nanoparticles for photodynamic imaging and therapy.

Optical imaging of cancer-related proteases using near-infrared fluorescence matrix metalloproteinase-sensitive and cathepsin B-sensitive probes.

Measurement of MMP Activity in Synovial Fluid in Cases of Osteoarthritis and Acute Inflammatory Conditions of the Knee Joints Using a Fluorogenic Peptide Probe-Immobilized Diagnostic Kit.

Tumor vasculature targeting following co-delivery of heparin-taurocholate conjugate and suberoylanilide hydroxamic acid using cationic nanolipoplex.

Iodinated photosensitizing chitosan: self-assembly into tumor-homing nanoparticles with enhanced singlet oxygen generation.

In vivo NIRF imaging of tumor targetability of nanosized liposomes in tumor-bearing mice.

Hydrotropic magnetic micelles for combined magnetic resonance imaging and cancer therapy.

The tumor accumulation and therapeutic efficacy of doxorubicin carried in calcium phosphate-reinforced polymer nanoparticles.

Systemic delivery of siRNA by chimeric capsid protein: tumor targeting and RNAi activity in vivo.

Tetraiodothyroacetic acid-tagged liposomes for enhanced delivery of anticancer drug to tumor tissue via integrin receptor.

Theranostic nanoparticles based on PEGylated hyaluronic acid for the diagnosis, therapy and monitoring of colon cancer.

Self-deprotonation and colorization of 1,3-bis(dicyanomethylidene)indan in polar media: a facile route to a minimal polymethine dye for NIR fluorescence imaging.

Tumor-homing poly-siRNA/glycol chitosan self-cross-linked nanoparticles for systemic siRNA delivery in cancer treatment.

Hyaluronic acid-ceramide-based optical/MR dual imaging nanoprobe for cancer diagnosis.

Dye/peroxalate aggregated nanoparticles with enhanced and tunable chemiluminescence for biomedical imaging of hydrogen peroxide.

Tumor-targeting multi-functional nanoparticles for theragnosis: new paradigm for cancer therapy.

In situ application of hydrogel-type fibrin-islet composite optimized for rapid glycemic control by subcutaneous xenogeneic porcine islet transplantation.

Effect of the stability and deformability of self-assembled glycol chitosan nanoparticles on tumor-targeting efficiency.

In vivo NIRF and MR dual-modality imaging using glycol chitosan nanoparticles.

Blood-pool multifunctional nanoparticles formed by temperature-induced phase transition for cancer-targeting therapy and molecular imaging.

In vivo quantitative measurement of arthritis activity based on hydrophobically modified glycol chitosan in inflammatory arthritis: more active than passive accumulation.

Structural modification of siRNA for efficient gene silencing.

Nanophotosensitizers toward advanced photodynamic therapy of Cancer.

Bioorthogonal copper-free click chemistry in vivo for tumor-targeted delivery of nanoparticles.

Phthalocyanine-aggregated polymeric nanoparticles as tumor-homing near-infrared absorbers for photothermal therapy of cancer.

The multilayer nanoparticles formed by layer by layer approach for cancer-targeting therapy.

Drug delivery by a self-assembled DNA tetrahedron for overcoming drug resistance in breast cancer cells.

Preparation and characterization of glycol chitin as a new thermogelling polymer for biomedical applications.

Robust PEGylated hyaluronic acid nanoparticles as the carrier of doxorubicin: mineralization and its effect on tumor targetability in vivo.

Self-assembled amphiphilic DNA-cholesterol/DNA-peptide hybrid duplexes with liposome-like structure for doxorubicin delivery.

Hyperacute direct thrombus imaging using computed tomography and gold nanoparticles.

Facile method to radiolabel glycol chitosan nanoparticles with (64)Cu via copper-free click chemistry for MicroPET imaging.

Photo-crosslinked hyaluronic acid nanoparticles with improved stability for in vivo tumor-targeted drug delivery.

Cancer cell-specific photoactivity of pheophorbide a-glycol chitosan nanoparticles for photodynamic therapy in tumor-bearing mice.

Ischemic brain imaging using fluorescent gold nanoprobes sensitive to reactive oxygen species.

Non-invasive optical imaging of matrix metalloproteinase activity with albumin-based fluorogenic nanoprobes during angiogenesis in a mouse hindlimb ischemia model.

Gadolinium-coordinated elastic nanogels for in vivo tumor targeting and imaging.

Conjugated polymer/photochromophore binary nanococktails: bistable photoswitching of near-infrared fluorescence for in vivo imaging.

Multilayer nanoparticles for sustained delivery of exenatide to treat type 2 diabetes mellitus.

Biocompatible glycol chitosan-coated gold nanoparticles for tumor-targeting CT imaging.

In vivo fluorescence imaging for cancer diagnosis using receptor-targeted epidermal growth factor-based nanoprobe.

Enhanced drug-loading and therapeutic efficacy of hydrotropic oligomer-conjugated glycol chitosan nanoparticles for tumor-targeted paclitaxel delivery.

Biocompatible gelatin nanoparticles for tumor-targeted delivery of polymerized siRNA in tumor-bearing mice.

Self-crosslinked human serum albumin nanocarriers for systemic delivery of polymerized siRNA to tumors.

Bioreducible hyaluronic acid conjugates as siRNA carrier for tumor targeting.

Characterization of partial ligation-induced carotid atherosclerosis model using dual-modality molecular imaging in ApoE knock-out mice.

Tumor-targeting transferrin nanoparticles for systemic polymerized siRNA delivery in tumor-bearing mice.

TNF-α gene silencing using polymerized siRNA/thiolated glycol chitosan nanoparticles for rheumatoid arthritis.

Hyaluronic acid derivative-coated nanohybrid liposomes for cancer imaging and drug delivery.

Hypoxia-responsive polymeric nanoparticles for tumor-targeted drug delivery.

Dextran sulfate-coated superparamagnetic iron oxide nanoparticles as a contrast agent for atherosclerosis imaging.

Oligomeric bile acid-mediated oral delivery of low molecular weight heparin.

Non-invasive optical imaging of cathepsin B with activatable fluorogenic nanoprobes in various metastatic models.

Complex adaptive therapeutic strategy (CATS) for cancer.

Chemical tumor-targeting of nanoparticles based on metabolic glycoengineering and click chemistry.

Functional transformations of bile acid transporters induced by high-affinity macromolecules.

Tumor-targeting multifunctional nanoparticles for siRNA delivery: recent advances in cancer therapy.

Cell labeling and tracking method without distorted signals by phagocytosis of macrophages.

Prediction of antiarthritic drug efficacies by monitoring active matrix metalloproteinase-3 (MMP-3) levels in collagen-induced arthritic mice using the MMP-3 probe.

Bioreducible carboxymethyl dextran nanoparticles for tumor-targeted drug delivery.

DNA amplification in neutral liposomes for safe and efficient gene delivery.

Theranostic nanoparticles for future personalized medicine.

Engineered protein nanoparticles for in vivo tumor detection.

Self-assembled glycol chitosan nanoparticles for disease-specific theranostics.

Prevention effect of orally active heparin conjugate on cancer-associated thrombosis.

Fluorescent dye labeled iron oxide/silica core/shell nanoparticle as a multimodal imaging probe.

Effect of HIFU treatment on tumor targeting efficacy of docetaxel-loaded Pluronic nanoparticles.

Nano carriers that enable co-delivery of chemotherapy and RNAi agents for treatment of drug-resistant cancers.

Sustained local delivery of oncolytic short hairpin RNA adenoviruses for treatment of head and neck cancer.

Accurate sequential detection of primary tumor and metastatic lymphatics using a temperature-induced phase transition nanoparticulate system.

Proteinticle/gold core/shell nanoparticles for targeted cancer therapy without nanotoxicity.

Tumor-targeting glycol chitosan nanoparticles as a platform delivery carrier in cancer diagnosis and therapy.

Glycol chitosan nanoparticles as specialized cancer therapeutic vehicles: sequential delivery of doxorubicin and Bcl-2 siRNA.

Erratum to: Fluorescent Dye Labeled Iron Oxide/Silica Core/Shell Nanoparticle as a Multimodal Imaging Probe.

Cancer-targeted MDR-1 siRNA delivery using self-cross-linked glycol chitosan nanoparticles to overcome drug resistance.

A polymeric conjugate foreignizing tumor cells for targeted immunotherapy in vivo.

Induced phenotype targeted therapy: radiation-induced apoptosis-targeted chemotherapy.

pH-controlled gas-generating mineralized nanoparticles: a theranostic agent for ultrasound imaging and therapy of cancers.

Design of a multicomponent peptide-woven nanocomplex for delivery of siRNA.

Molecular imaging and targeted drug delivery using albumin-based nanoparticles.

Directed molecular assembly into a biocompatible photosensitizing nanocomplex for locoregional photodynamic therapy.

Direct observation of interactions of silk-elastinlike protein polymer with adenoviruses and elastase.

Hyaluronic acid nanoparticles for active targeting atherosclerosis.

Hyaluronic acid-siRNA conjugate/reducible polyethylenimine complexes for targeted siRNA delivery.

Co-delivery of chemosensitizing siRNA and an anticancer agent via multiple monocomplexation-induced hydrophobic association.

Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles.

Corrigendum: Functional transformations of bile acid transporters induced by high-affinity macromolecules.

Design of a platform technology for systemic delivery of siRNA to tumours using rolling circle transcription.

Notch1 targeting siRNA delivery nanoparticles for rheumatoid arthritis therapy.

Enhanced Cytoplasmic Delivery of RAGE siRNA Using Bioreducible Polyethylenimine-based Nanocarriers for Myocardial Gene Therapy.

Co-delivery of VEGF and Bcl-2 dual-targeted siRNA polymer using a single nanoparticle for synergistic anti-cancer effects in vivo.

Biolighted Nanotorch Capable of Systemic Self-Delivery and Diagnostic Imaging.

Optical Imaging and Gene Therapy with Neuroblastoma-Targeting Polymeric Nanoparticles for Potential Theranostic Applications.

Echogenic Glycol Chitosan Nanoparticles for Ultrasound-Triggered Cancer Theranostics.

Theranostic gas-generating nanoparticles for targeted ultrasound imaging and treatment of neuroblastoma.

Development of highly efficient nanocarrier-mediated delivery approaches for cancer therapy.

Bioorthogonal Copper Free Click Chemistry for Labeling and Tracking of Chondrocytes In Vivo.

Doxorubicin/gold-loaded core/shell nanoparticles for combination therapy to treat cancer through the enhanced tumor targeting.

ROS-generating TiO2 nanoparticles for non-invasive sonodynamic therapy of cancer.

In vivo monitoring of angiogenesis in a mouse hindlimb ischemia model using fluorescent peptide-based probes.

Size-engineered biocompatible polymeric nanophotosensitizer for locoregional photodynamic therapy of cancer.

T1-Weighted MR imaging of liver tumor by gadolinium-encapsulated glycol chitosan nanoparticles without non-specific toxicity in normal tissues.

Delivery strategies and potential targets for siRNA in major cancer types.

Doxorubicin/heparin composite nanoparticles for caspase-activated prodrug chemotherapy.

Targeted Nanotheranostics for Future Personalized Medicine: Recent Progress in Cancer Therapy.

Predicting the in vivo accumulation of nanoparticles in tumor based on in vitro macrophage uptake and circulation in zebrafish.

Advances and hurdles to clinical translation of RNAi therapeutics.

The multilayer nanoparticles for deep penetration of docetaxel into tumor parenchyma to overcome tumor microenvironment.

Reducible Polyethylenimine Nanoparticles for Efficient siRNA Delivery in Corneal Neovascularization Therapy.

Chemical gas-generating nanoparticles for tumor-targeted ultrasound imaging and ultrasound-triggered drug delivery.

Multicomponent, peptide-targeted glycol chitosan nanoparticles containing ferrimagnetic iron oxide nanocubes for bladder cancer multimodal imaging.

Long-Circulating Au-TiO2 Nanocomposite as a Sonosensitizer for ROS-Mediated Eradication of Cancer.