Pedro Cabrales

Microvascular oxygen distribution in awake hamster window chamber model during hyperoxia.

Measurement of the cardiac output in small animals by thermodilution.

Microcirculatory changes during chronic adaptation to hypoxia.

Radial displacement of red blood cells during hemodilution and the effect on arteriolar oxygen profile.

Microlymphatic and tissue oxygen tension in the rat mesentery.

Microvascular pressure and functional capillary density in extreme hemodilution with low- and high-viscosity dextran and a low-viscosity Hb-based O2 carrier.

Microvascular PO2 during extreme hemodilution with hemoglobin site specifically PEGylated at Cys-93(beta) in hamster window chamber.

Oxygen delivery and consumption in the microcirculation after extreme hemodilution with perfluorocarbons.

Oxygen-carrying blood substitutes: a microvascular perspective.

Increased tissue PO2 and decreased O2 delivery and consumption after 80% exchange transfusion with polymerized hemoglobin.

Resuscitation from hemorrhagic shock with MalPEG-albumin: comparison with MalPEG-hemoglobin.

Hyperosmotic-hyperoncotic versus hyperosmotic-hyperviscous: small volume resuscitation in hemorrhagic shock.

Microvascular perfusion upon exchange transfusion with stored red blood cells in normovolemic anemic conditions.

Oxygen distribution and respiration by the microcirculation.

Oxygen transport by low and normal oxygen affinity hemoglobin vesicles in extreme hemodilution.

Microvascular oxygen delivery and consumption following treatment with verapamil.

Elevated plasma viscosity in extreme hemodilution increases perivascular nitric oxide concentration and microvascular perfusion.

Alginate plasma expander maintains perfusion and plasma viscosity during extreme hemodilution.

Effects of extreme hemodilution with hemoglobin-based O2 carriers on microvascular pressure.

Oxygen release from low and normal P50 Hb vesicles in transiently occluded arterioles of the hamster window model.

Increase plasma viscosity sustains microcirculation after resuscitation from hemorrhagic shock and continuous bleeding.

Early difference in tissue pH and microvascular hemodynamics in hemorrhagic shock resuscitation using polyethylene glycol-albumin- and hydroxyethyl starch-based plasma expanders.

Blood viscosity: a factor in tissue survival?

Extreme hemodilution with PEG-hemoglobin vs. PEG-albumin.

Effect of oxygen consumption by measuring method on PO2 transients associated with the passage of erythrocytes in capillaries of rat mesentery.

Role of endothelial nitric oxide in microvascular oxygen delivery and consumption.

The vascular wall as a regulator of tissue oxygenation.

Nitric oxide regulation of microvascular oxygen exchange during hypoxia and hyperoxia.

Microvascular effects following treatment with polyethylene glycol-albumin in lipopolysaccharide-induced endotoxemia.

Oxygen release from arterioles with normal flow and no-flow conditions.

Increased cardiac output and microvascular blood flow during mild hemoconcentration in hamster window model.

Blood viscosity maintains microvascular conditions during normovolemic anemia independent of blood oxygen-carrying capacity.

Can the effects of vasoactivity of molecular hemoglobin-based plasma expanders be ignored?

Plasma viscosity regulates systemic and microvascular perfusion during acute extreme anemic conditions.

Microvascular perspective of oxygen-carrying and -noncarrying blood substitutes.

Dissociation of local nitric oxide concentration and vasoconstriction in the presence of cell-free hemoglobin oxygen carriers.

Hemorrhagic shock resuscitation with carbon monoxide saturated blood.

Deferoxamine lowers tissue damage after 80% exchange transfusion with polymerized hemoglobin.

Perfluorocarbon in microcirculation during ischemia reperfusion.

Microvascular and systemic effects following top load administration of saturated carbon monoxide-saline solution.

Microvascular and capillary perfusion following glycocalyx degradation.

Excessive erythrocytosis does not elevate capillary oxygen delivery in subcutaneous mouse tissue.

Is resuscitation from hemorrhagic shock limited by blood oxygen-carrying capacity or blood viscosity?

Effects of erythrocyte flexibility on microvascular perfusion and oxygenation during acute anemia.

Transfusion restores blood viscosity and reinstates microvascular conditions from hemorrhagic shock independent of oxygen carrying capacity.

New phosphorescence quenching oxygen measurements technique yields unusual tissue and plasma PO2 distributions.

Time-dependant oxygen partial pressure in capillaries and tissue in the hamster window chamber model.

Resuscitation from hemorrhagic shock with hydroxyethyl starch and coagulation changes.

Lowering of blood pressure by increasing hematocrit with non nitric oxide scavenging red blood cells.

Modulation of perfusion and oxygenation by red blood cell oxygen affinity during acute anemia.

Terminal lymphatics: the potential "lethal corner" in the distribution of tissue pO2.

Increased hematocrit and reduced blood pressure following control of glycemia in diabetes.

Increased plasma viscosity prolongs microhemodynamic conditions during small volume resuscitation from hemorrhagic shock.

Survival time in severe hemorrhagic shock after perioperative hemodilution is longer with PEG-conjugated human serum albumin than with HES 130/0.4: a microvascular perspective.

Microvascular experimental evidence on the relative significance of restoring oxygen carrying capacity vs. blood viscosity in shock resuscitation.

Oxygen transport during hemodilution with a perfluorocarbon-based oxygen carrier: effect of altitude and hyperoxia.

Volume resuscitation from hemorrhagic shock with albumin and hexaPEGylated human serum albumin.

Balance between vasoconstriction and enhanced oxygen delivery.

Polymerized bovine hemoglobin can improve small-volume resuscitation from hemorrhagic shock in hamsters.

Isovolemic exchange transfusion with increasing concentrations of low oxygen affinity hemoglobin solution limits oxygen delivery due to vasoconstriction.

Microcirculatory effects of changing blood hemoglobin oxygen affinity during hemorrhagic shock resuscitation in an experimental model.

Blood pressure reduction due to hemoglobin glycosylation in type 2 diabetic patients.

Exogenous nitric oxide induces protection during hemorrhagic shock.

Nonobese, exercising children diagnosed with dyslipidemia have normal C-reactive protein.

Will fixing the vasoactivity caused by hemoglobin-based oxygen carriers be enough?

Hematocrit and mean arterial blood pressure in pre- and postmenopause women.

Hexa-thiocarbamoyl phenyl PEG5K Hb: vasoactivity and structure: influence of rigidity of the conjugation linkage on the PEGylation induced plasma expander-like solution properties of PEG-Hb adducts.

Effects of the molecular mass of tense-state polymerized bovine hemoglobin on blood pressure and vasoconstriction.

The physics of oxygen delivery: facts and controversies.

Low dose nitrite enhances perfusion after fluid resuscitation from hemorrhagic shock.

Nitrate and nitrite in biology, nutrition and therapeutics.

Tissue oxygenation after exchange transfusion with ultrahigh-molecular-weight tense- and relaxed-state polymerized bovine hemoglobins.

Murine cerebral malaria is associated with a vasospasm-like microcirculatory dysfunction, and survival upon rescue treatment is markedly increased by nimodipine.

Blood pressure directly correlates with blood viscosity in diabetes type 1 children but not in normals.

Synthesis, biophysical properties and pharmacokinetics of ultrahigh molecular weight tense and relaxed state polymerized bovine hemoglobins.

Low oxygen-affinity hemoglobin solution increases oxygenation of partially ischemic tissue during acute anemia.

Sustained release nitric oxide from long-lived circulating nanoparticles.

The variability of blood pressure due to small changes of hematocrit.

Perfusion vs. oxygen delivery in transfusion with "fresh" and "old" red blood cells: the experimental evidence.

Cardiac systolic function recovery after hemorrhage determines survivability during shock.

Tissue oxidative metabolism after extreme hemodilution with PEG-conjugated hemoglobin.

Effects of plasma viscosity modulation on cardiac function during moderate hemodilution.

Biophysical properties and oxygenation potential of high-molecular-weight glutaraldehyde-polymerized human hemoglobins maintained in the tense and relaxed quaternary states.

Reversal of hemoglobin-induced vasoconstriction with sustained release of nitric oxide.

Cardiac mechanoenergetic cost of elevated plasma viscosity after moderate hemodilution.

Synthesis and biophysical properties of polymerized human serum albumin.

Improved resuscitation from hemorrhagic shock with Ringer's lactate with increased viscosity in the hamster window chamber model.

Synthesis and biophysical properties of polymerized human serum albumin.

Delaying blood transfusion in experimental acute anemia with a perfluorocarbon emulsion.

Small-volume resuscitation from hemorrhagic shock using high-molecular-weight tense-state polymerized hemoglobins.

Exogenous nitric oxide prevents cardiovascular collapse during hemorrhagic shock.

Nitric oxide protection against murine cerebral malaria is associated with improved cerebral microcirculatory physiology.

Integration of cardiovascular regulation by the blood/endothelium cell-free layer.

Synthesis, biophysical properties, and oxygenation potential of variable molecular weight glutaraldehyde-polymerized bovine hemoglobins with low and high oxygen affinity.

Exogenous nitric oxide decreases brain vascular inflammation, leakage and venular resistance during Plasmodium berghei ANKA infection in mice.

Nanoengineering bactericidal nitric oxide therapies.

Exogenous intravascular nitric oxide enhances ventricular function after hemodilution with plasma expander.

Small-volume resuscitation from hemorrhagic shock with polymerized human serum albumin.

Nonlinear cardiovascular regulation consequent to changes in blood viscosity.

Effects of acute anemia and hyperoxia on oxygen distribution.

Simulation of NO and O(2) transport facilitated by polymerized hemoglobin solutions in an arteriole that takes into account wall shear stress-induced NO production.

Hypervolemic infusion of Lumbricus terrestris erythrocruorin purified by tangential-flow filtration.