Physiology and Experimental Medicine Program
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COMP-angiopoietin-1 promotes wound healing through enhanced angiogenesis, lymphangiogenesis, and blood flow in a diabetic mouse model.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2006 | Pubmed ID: 16543381
Intestinal and peri-tumoral lymphatic endothelial cells are resistant to radiation-induced apoptosis.
Biochemical and biophysical research communications Jun, 2006 | Pubmed ID: 16690025
Angiogenic role of LYVE-1-positive macrophages in adipose tissue.
Circulation research Mar, 2007 | Pubmed ID: 17272806
Lymphatic development in mouse small intestine.
Developmental dynamics : an official publication of the American Association of Anatomists Jul, 2007 | Pubmed ID: 17576138
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells.
Nature Apr, 2009 | Pubmed ID: 19252478
COMP-angiopoietin-1 enhances skeletal muscle blood flow and insulin sensitivity in mice.
American journal of physiology. Endocrinology and metabolism Aug, 2009 | Pubmed ID: 19491299
Multifaceted role of vascular endothelial growth factor signaling in adult tissue physiology: an emerging concept with clinical implications.
Current opinion in hematology May, 2010 | Pubmed ID: 20216210
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming.
Cell stem cell Jul, 2010 | Pubmed ID: 20621051
Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage.
Cancer cell Aug, 2010 | Pubmed ID: 20708158
Induced pluripotent stem cell lines derived from equine fibroblasts.
Stem cell reviews Sep, 2011 | Pubmed ID: 21347602
Nestin is not essential for development of the CNS but required for dispersion of acetylcholine receptor clusters at the area of neuromuscular junctions.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2011 | Pubmed ID: 21832185
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.
Cell Sep, 2011 | Pubmed ID: 21924763
Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function.
Cell Oct, 2012 | Pubmed ID: 23063127
Highly efficient site-specific transgenesis in cancer cell lines.
Molecular cancer , 2012 | Pubmed ID: 23231822
Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis.
Cell metabolism Jan, 2013 | Pubmed ID: 23312284
MBNL proteins repress ES-cell-specific alternative splicing and reprogramming.
Nature Jun, 2013 | Pubmed ID: 23739326
VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy.
EMBO molecular medicine Sep, 2013 | Pubmed ID: 23853117
Obesity-associated variants within FTO form long-range functional connections with IRX3.
Nature Mar, 2014 | Pubmed ID: 24646999
Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye.
EMBO molecular medicine May, 2014 | Pubmed ID: 24705878
iPS Cell-Derived Cardiogenicity is Hindered by Sustained Integration of Reprogramming Transgenes.
Circulation. Cardiovascular genetics Jul, 2014 | Pubmed ID: 25077947
Trophoblast-Specific Reduction of VEGFA Alters Placental Gene Expression and Maternal Cardiovascular Function in Mice.
Biology of reproduction Oct, 2014 | Pubmed ID: 25122061
A lymphatic defect causes ocular hypertension and glaucoma in mice.
The Journal of clinical investigation Oct, 2014 | Pubmed ID: 25202984
Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging.
Aging cell Oct, 2015 | Pubmed ID: 26111777
Generation, Characterization, and Multilineage Potency of Mesenchymal-Like Progenitors Derived from Equine Induced Pluripotent Stem Cells.
Stem cells and development Jan, 2016 | Pubmed ID: 26414480
Antisenescence effect of mouse embryonic stem cell conditioned medium through a PDGF/FGF pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Mar, 2016 | Pubmed ID: 26675707
Intermittent fasting promotes adipose thermogenesis and metabolic homeostasis via VEGF-mediated alternative activation of macrophage.
Cell research Nov, 2017 | Pubmed ID: 29039412
Flow Cytometry and Lineage Tracing Study for Identification of Adipocyte Precursor Cell (APC) Populations.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29564767
Adipose Tissue and Modulation of Hypertension.
Current hypertension reports Sep, 2018 | Pubmed ID: 30229358
Linking a cell-division gene and a suicide gene to define and improve cell therapy safety.
Nature 11, 2018 | Pubmed ID: 30429614
CD36 mediates albumin transcytosis by dermal but not lung microvascular endothelial cells: role in fatty acid delivery.
American journal of physiology. Lung cellular and molecular physiology May, 2019 | Pubmed ID: 30702342
Thermogenesis-independent metabolic benefits conferred by isocaloric intermittent fasting in ob/ob mice.
Scientific reports Feb, 2019 | Pubmed ID: 30792482
Toll-like receptor 2 expression on c-kit cells tracks the emergence of embryonic definitive hematopoietic progenitors.
Nature communications Nov, 2019 | Pubmed ID: 31729371
1Department of Biochemistry and Molecular Biology and Smart-aging Convergence Research Center, College of Medicine, Yeungnam University,
2Physiology and Experimental Medicine Program, The Hospital for Sick Children Research Institute,
3Department of Laboratory Medicine and Pathobiology, University of Toronto
Yanqing Jiang*,1,
Joanna Lan-Hing Yeung*,1,
Ju Hee Lee1,2,
James An1,
Patrick E. Steadman3,
Jae-Ryong Kim4,
Hoon-Ki Sung1,2,5
1Translational Medicine Program, The Hospital for Sick Children,
2Department of Laboratory Medicine and Pathobiology, University of Toronto,
3Neurosciences & Mental Health Program, The Hospital for Sick Children,
4Department of Biochemistry and Molecular Biology, Smart-Aging Convergence Research Center, College of Medicine, Yeungnam University,
5Banting and Best Diabetes Centre, University of Toronto
1, University of Ottawa Heart Institute,
2Department of Cellular and Molecular Medicine, University of Ottawa,
3Translational Medicine Program, The Hospital for Sick Children,
4Department of Laboratory Medicine and Pathobiology, University of Toronto,
5Banting and Best Diabetes Centre, University of Toronto
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