Computational and Systems Biology,
Genome Institute of Singapore,
Computational and Systems Biology, Genome Institute of Singapore
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Automatic prediction of protein domains from sequence information using a hybrid learning system.
Bioinformatics (Oxford, England) Jun, 2004 | Pubmed ID: 14962932
Computing the P-value of the information content from an alignment of multiple sequences.
Bioinformatics (Oxford, England) Jun, 2005 | Pubmed ID: 15961473
Apples to apples: improving the performance of motif finders and their significance analysis in the Twilight Zone.
Bioinformatics (Oxford, England) Jul, 2006 | Pubmed ID: 16873498
FAST: Fourier transform based algorithms for significance testing of ungapped multiple alignments.
Bioinformatics (Oxford, England) Feb, 2008 | Pubmed ID: 18180239
Scaffolding and validation of bacterial genome assemblies using optical restriction maps.
Bioinformatics (Oxford, England) May, 2008 | Pubmed ID: 18356192
The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus).
Nature Apr, 2008 | Pubmed ID: 18432245
Statistical methods for detecting differentially abundant features in clinical metagenomic samples.
PLoS computational biology Apr, 2009 | Pubmed ID: 19360128
Complete genome sequence of Aggregatibacter (Haemophilus) aphrophilus NJ8700.
Journal of bacteriology Jul, 2009 | Pubmed ID: 19447908
Parametric complexity of sequence assembly: theory and applications to next generation sequencing.
Journal of computational biology : a journal of computational molecular cell biology Jul, 2009 | Pubmed ID: 19580519
2009 Swine-origin influenza A (H1N1) resembles previous influenza isolates.
PloS one , 2009 | Pubmed ID: 19636415
Genomic characterization of the Yersinia genus.
Genome biology , 2010 | Pubmed ID: 20047673
Alignment and clustering of phylogenetic markers--implications for microbial diversity studies.
BMC bioinformatics Mar, 2010 | Pubmed ID: 20334679
Finding biologically accurate clusterings in hierarchical tree decompositions using the variation of information.
Journal of computational biology : a journal of computational molecular cell biology Mar, 2010 | Pubmed ID: 20377460
Finishing genomes with limited resources: lessons from an ensemble of microbial genomes.
BMC genomics Apr, 2010 | Pubmed ID: 20398345
Sequencing and genome assembly using next-generation technologies.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20835789
GiRaF: robust, computational identification of influenza reassortments via graph mining.
Nucleic acids research Mar, 2011 | Pubmed ID: 21177643
Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes.
Genome research May, 2011 | Pubmed ID: 21467267
Opera: reconstructing optimal genomic scaffolds with high-throughput paired-end sequences.
Journal of computational biology : a journal of computational molecular cell biology Nov, 2011 | Pubmed ID: 21929371
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer.
Nature medicine , 2012 | Pubmed ID: 22426421
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes.
Nature genetics Apr, 2012 | Pubmed ID: 22484628
Genome mapping on nanochannel arrays for structural variation analysis and sequence assembly.
Nature biotechnology Jul, 2012 | Pubmed ID: 22797562
A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients.
The Journal of infectious diseases Jul, 2012 | Pubmed ID: 22807519
Long span DNA paired-end-tag (DNA-PET) sequencing strategy for the interrogation of genomic structural mutations and fusion-point-guided reconstruction of amplicons.
PloS one , 2012 | Pubmed ID: 23029419
LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets.
Nucleic acids research Dec, 2012 | Pubmed ID: 23066108
The draft genome of sweet orange (Citrus sinensis).
Nature genetics Jan, 2013 | Pubmed ID: 23179022
Whole-genome reconstruction and mutational signatures in gastric cancer.
Genome biology Dec, 2012 | Pubmed ID: 23237666
Sequence assembly demystified.
Nature reviews. Genetics Mar, 2013 | Pubmed ID: 23358380
Species identification and profiling of complex microbial communities using shotgun Illumina sequencing of 16S rRNA amplicon sequences.
PloS one , 2013 | Pubmed ID: 23579286
Genome Sequencing of Four Strains of Rickettsia prowazekii, the Causative Agent of Epidemic Typhus, Including One Flying Squirrel Isolate.
Genome announcements Jun, 2013 | Pubmed ID: 23814035
Next-generation whole genome sequencing of dengue virus.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 24696338
The Opisthorchis viverrini genome provides insights into life in the bile duct.
Nature communications Jul, 2014 | Pubmed ID: 25007141
Genomic characterization of three unique Dehalococcoides that respire on persistent polychlorinated biphenyls.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2014 | Pubmed ID: 25028492
Systems consequences of amplicon formation in human breast cancer.
Genome research Oct, 2014 | Pubmed ID: 25186909
Draft Genome Sequence of Polychlorinated Biphenyl-Dechlorinating Dehalococcoides mccartyi Strain SG1, Which Carries a Circular Putative Plasmid.
Genome announcements Oct, 2014 | Pubmed ID: 25278523
BAsE-Seq: a method for obtaining long viral haplotypes from short sequence reads.
Genome biology , 2014 | Pubmed ID: 25406369
The importance of study design for detecting differentially abundant features in high-throughput experiments.
Genome biology Dec, 2014 | Pubmed ID: 25517037
Patient-specific driver gene prediction and risk assessment through integrated network analysis of cancer omics profiles.
Nucleic acids research Apr, 2015 | Pubmed ID: 25572314
High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer.
Genome biology Feb, 2015 | Pubmed ID: 25808843
Cloning and variation of ground state intestinal stem cells.
Nature Jun, 2015 | Pubmed ID: 26040716
Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity.
Cell reports Jul, 2015 | Pubmed ID: 26146084
Tracking Dengue Virus Intra-host Genetic Diversity during Human-to-Mosquito Transmission.
PLoS neglected tropical diseases , 2015 | Pubmed ID: 26325059
Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints.
PLoS neglected tropical diseases , 2015 | Pubmed ID: 26327586
Direct whole-genome deep-sequencing of human respiratory syncytial virus A and B from Vietnamese children identifies distinct patterns of inter- and intra-host evolution.
The Journal of general virology Dec, 2015 | Pubmed ID: 26407694
In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cells.
The Journal of pathology Mar, 2016 | Pubmed ID: 26415052
Genus-Wide Comparative Genomics of Malassezia Delineates Its Phylogeny, Physiology, and Niche Adaptation on Human Skin.
PLoS genetics Nov, 2015 | Pubmed ID: 26539826
Single-molecule optical genome mapping of a human HapMap and a colorectal cancer cell line.
GigaScience , 2015 | Pubmed ID: 26719794
Mutational spectrum of Barrett's stem cells suggests paths to initiation of a precancerous lesion.
Nature communications Jan, 2016 | Pubmed ID: 26783136
OPTIMA: sensitive and accurate whole-genome alignment of error-prone genomic maps by combinatorial indexing and technology-agnostic statistical analysis.
GigaScience , 2016 | Pubmed ID: 26793302
Predicting microbial interactions through computational approaches.
Methods (San Diego, Calif.) Jun, 2016 | Pubmed ID: 27025964
Fast and sensitive mapping of nanopore sequencing reads with GraphMap.
Nature communications Apr, 2016 | Pubmed ID: 27079541
OPERA-LG: efficient and exact scaffolding of large, repeat-rich eukaryotic genomes with performance guarantees.
Genome biology May, 2016 | Pubmed ID: 27169502
In Vivo Mapping of Eukaryotic RNA Interactomes Reveals Principles of Higher-Order Organization and Regulation.
Molecular cell May, 2016 | Pubmed ID: 27184079
@MInter: automated text-mining of microbial interactions.
Bioinformatics (Oxford, England) Oct, 2016 | Pubmed ID: 27312413
Tissue Microbiome Profiling Identifies an Enrichment of Specific Enteric Bacteria in Opisthorchis viverrini Associated Cholangiocarcinoma.
EBioMedicine Jun, 2016 | Pubmed ID: 27428430
INC-Seq: accurate single molecule reads using nanopore sequencing.
GigaScience Aug, 2016 | Pubmed ID: 27485345
Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare.
Nature microbiology Jul, 2016 | Pubmed ID: 27562258
Fast and accurate de novo genome assembly from long uncorrected reads.
Genome research May, 2017 | Pubmed ID: 28100585
Development of a genetically programed vanillin-sensing bacterium for high-throughput screening of lignin-degrading enzyme libraries.
Biotechnology for biofuels , 2017 | Pubmed ID: 28174601
Transcriptomics Analysis Reveals Putative Genes Involved in Biofilm Formation and Biofilm-associated Drug Resistance of Enterococcus faecalis.
Journal of endodontics Apr, 2017 | Pubmed ID: 28457636
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