Katz Family Drug Discovery Center and Division of Nephrology and Hypertension,
Department of Medicine,
Department of Cell Biology and Anatomy,
Katz Family Drug Discovery Center and Division of Nephrology and Hypertension, Department of Medicine
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Novel concepts in understanding and management of glomerular proteinuria.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Jun, 2002 | Pubmed ID: 12032178
Hypereosinophilic syndrome associated with heterozygous factor V gene mutation: an unusual combination resulting in an acute coronary syndrome and recurrent cerebral stroke-a case report.
Angiology Mar-Apr, 2004 | Pubmed ID: 15026880
Induction of B7-1 in podocytes is associated with nephrotic syndrome.
The Journal of clinical investigation May, 2004 | Pubmed ID: 15146236
Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.
The Journal of clinical investigation May, 2005 | Pubmed ID: 15841212
Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3.
The Journal of cell biology May, 2005 | Pubmed ID: 15883195
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function.
Nature genetics Jul, 2005 | Pubmed ID: 15924139
Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling.
Nature cell biology May, 2006 | Pubmed ID: 16622418
Nuclear relocation of the nephrin and CD2AP-binding protein dendrin promotes apoptosis of podocytes.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2007 | Pubmed ID: 17537921
Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes.
The American journal of pathology Aug, 2007 | Pubmed ID: 17569780
Gain-of-function RAF1 mutations cause Noonan and LEOPARD syndromes with hypertrophic cardiomyopathy.
Nature genetics Aug, 2007 | Pubmed ID: 17603483
Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton.
Trends in cell biology Sep, 2007 | Pubmed ID: 17804239
Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes.
Molecular and cellular biology Dec, 2007 | Pubmed ID: 17923693
The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.
Nature medicine Sep, 2008 | Pubmed ID: 18724379
Mpv17l protects against mitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2008 | Pubmed ID: 18772386
Mast cells, macrophages, and crown-like structures distinguish subcutaneous from visceral fat in mice.
Journal of lipid research Mar, 2011 | Pubmed ID: 21148461
COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness.
The Journal of clinical investigation May, 2011 | Pubmed ID: 21540551
Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival.
The Journal of biological chemistry Jul, 2011 | Pubmed ID: 21613219
Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.
The American journal of pathology Oct, 2011 | Pubmed ID: 21839714
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival.
The Journal of clinical investigation Oct, 2011 | Pubmed ID: 21911934
FGF23 induces left ventricular hypertrophy.
The Journal of clinical investigation Nov, 2011 | Pubmed ID: 21985788
Rescue of tropomyosin deficiency in Drosophila and human cancer cells by synaptopodin reveals a role of tropomyosin α in RhoA stabilization.
The EMBO journal Feb, 2012 | Pubmed ID: 22157816
Acute pulmonary embolism in patients with obstructive sleep apnoea: does it affect the severity of sleep-disordered breathing?
Sleep & breathing = Schlaf & Atmung Dec, 2012 | Pubmed ID: 22187134
TRPC6 in podocytes: questions and commentary on the article by Jiang et al., 'Over-expressing transient receptor potential cation channel 6 in podocytes induces cytoskeleton rearrangement through increases of intracellular Ca21 and RhoA activation'.
Experimental biology and medicine (Maywood, N.J.) Dec, 2011 | Pubmed ID: 22242226
Differences of cardiac output measurements by open-circuit acetylene uptake in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: a cohort study.
Respiratory research Mar, 2012 | Pubmed ID: 22409387
Fibroblast growth factor 23 and the heart.
Current opinion in nephrology and hypertension Jul, 2012 | Pubmed ID: 22531163
Detection of exercise-induced pulmonary arterial hypertension by cardiopulmonary exercise testing.
Clinical cardiology Sep, 2012 | Pubmed ID: 22588968
Ventilatory efficiency testing as prognostic value in patients with pulmonary hypertension.
BMC pulmonary medicine Jun, 2012 | Pubmed ID: 22676304
Dynamin-mediated Nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells.
The Journal of biological chemistry Aug, 2012 | Pubmed ID: 22718751
Regarding Maas's editorial letter on serum suPAR levels.
Kidney international Aug, 2012 | Pubmed ID: 22846820
Expression of fgf23 and αklotho in developing embryonic tissues and adult kidney of the zebrafish, Danio rerio.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Dec, 2012 | Pubmed ID: 22885518
The calcineurin-NFAT pathway allows for urokinase receptor-mediated beta3 integrin signaling to cause podocyte injury.
Journal of molecular medicine (Berlin, Germany) Dec, 2012 | Pubmed ID: 23015147
ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling.
The Journal of clinical investigation Aug, 2013 | Pubmed ID: 23867502
Essential role for synaptopodin in dendritic spine plasticity of the developing hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2013 | Pubmed ID: 23884954
Paricalcitol downregulates myocardial renin-angiotensin and fibroblast growth factor expression and attenuates cardiac hypertrophy in uremic rats.
American journal of hypertension May, 2014 | Pubmed ID: 24072555
Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease.
The Journal of biological chemistry Dec, 2013 | Pubmed ID: 24194522
Abatacept in B7-1-positive proteinuric kidney disease.
The New England journal of medicine Dec, 2013 | Pubmed ID: 24206430
Signal transduction in podocytes--spotlight on receptor tyrosine kinases.
Nature reviews. Nephrology Feb, 2014 | Pubmed ID: 24394191
In vivo imaging of kidney glomeruli transplanted into the anterior chamber of the mouse eye.
Scientific reports Jan, 2014 | Pubmed ID: 24464028
Treatment of established left ventricular hypertrophy with fibroblast growth factor receptor blockade in an animal model of CKD.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Nov, 2014 | Pubmed ID: 24875663
Sphingomyelinase-like phosphodiesterase 3b expression levels determine podocyte injury phenotypes in glomerular disease.
Journal of the American Society of Nephrology : JASN Jan, 2015 | Pubmed ID: 24925721
Klotho and phosphate are modulators of pathologic uremic cardiac remodeling.
Journal of the American Society of Nephrology : JASN Jun, 2015 | Pubmed ID: 25326585
The prevalence of sleep-disordered breathing among survivors of acute pulmonary embolism.
Sleep & breathing = Schlaf & Atmung Mar, 2016 | Pubmed ID: 26115650
Hunt for the culprit of cardiovascular injury in kidney disease.
Cardiovascular research Nov, 2015 | Pubmed ID: 26395966
Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy.
Cell metabolism Dec, 2015 | Pubmed ID: 26437603
Induction of cardiac FGF23/FGFR4 expression is associated with left ventricular hypertrophy in patients with chronic kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Jul, 2016 | Pubmed ID: 26681731
The role of fibroblast growth factor 23 and Klotho in uremic cardiomyopathy.
Current opinion in nephrology and hypertension Jul, 2016 | Pubmed ID: 27219043
The Effect of a Gluten-Free Diet in Children With Difficult-to-Manage Nephrotic Syndrome.
Pediatrics Jul, 2016 | Pubmed ID: 27338701
Fibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease.
Kidney international Nov, 2016 | Pubmed ID: 27457912
Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury.
The Journal of clinical investigation Sep, 2016 | Pubmed ID: 27482889
Cardiac actions of fibroblast growth factor 23.
Bone Oct, 2016 | Pubmed ID: 27725315
Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease.
Kidney international Mar, 2017 | Pubmed ID: 28017325
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