Qinghua Wang

The phosphatidylinositol 3-kinase inhibitor LY294002 potently blocks K(V) currents via a direct mechanism.

Control of synaptic strength, a novel function of Akt.

DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a.

Ubiquitin recognition by the DNA repair protein hHR23a.

WormBase: a multi-species resource for nematode biology and genomics.

Ubiquitin family proteins and their relationship to the proteasome: a structural perspective.

WormBase: a comprehensive data resource for Caenorhabditis biology and genomics.

Chemical shift assignments of the (poly)ubiquitin-binding region of the proteasome subunit S5a.

Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition.

[Effects of NaCl stress on Ca, Mg, Fe and Zn contents of different apple organs].

Determining protein topology from skeletons of secondary structures.

Role of Cdx-2 in insulin and proglucagon gene expression: a study using the RIN-1056A cell line with an inducible gene expression system.

Folding of small helical proteins assisted by small-angle X-ray scattering profiles.

Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system.

Differences in the neuronal stem cells survival, neuronal differentiation and neurological improvement after transplantation of neural stem cells between mild and severe experimental traumatic brain injury.

Neural stem cells transplantation in cortex in a mouse model of Alzheimer's disease.

Activin receptor-like kinase 7 induces apoptosis through up-regulation of Bax and down-regulation of Xiap in normal and malignant ovarian epithelial cell lines.

Prediction of acute renal allograft rejection in early post-transplantation period by soluble CD30.

Fufang cangzhu tang for treatment of senile obesity or overweight complicated with impaired glucose tolerance --a clinical observation in 32 cases.

The neuronal Ca2+ sensor protein visinin-like protein-1 is expressed in pancreatic islets and regulates insulin secretion.

Remarkable variation in maize genome structure inferred from haplotype diversity at the bz locus.

Efficacy of DNA immunization with F and G protein genes of Nipah virus.

The SH3 domain of a M7 interacts with its C-terminal proline-rich region.

Normal mode refinement of anisotropic thermal parameters for a supramolecular complex at 3.42-A crystallographic resolution.

Normal-mode refinement of anisotropic thermal parameters for potassium channel KcsA at 3.2 A crystallographic resolution.

Molecular docking study of the interactions between the thioesterase domain of human fatty acid synthase and its ligands.

Study of the surface structure of butterfly wings using the scanning electron microscopic moiré method.

Structural basis for receptor specificity of influenza B virus hemagglutinin.

Crystal structure of unliganded influenza B virus hemagglutinin.

Increased beta-cell apoptosis and impaired insulin signaling pathway contributes to the onset of diabetes in OLETF rats.

Insulin as a physiological modulator of glucagon secretion.

Epac is involved in cAMP-stimulated proglucagon expression and hormone production but not hormone secretion in pancreatic alpha- and intestinal L-cell lines.

Diversifying selective pressure on influenza B virus hemagglutinin.

A new mark shearing technique for strain measurement using digital image correlation method.

Structural improvement of unliganded simian immunodeficiency virus gp120 core by normal-mode-based X-ray crystallographic refinement.

Application of normal-mode refinement to X-ray crystal structures at the lower resolution limit.

POU homeodomain protein Oct-1 functions as a sensor for cyclic AMP.

[Analysis of monoclonal antibody binding sites in ovine prion protein].

Functional characterization of hyperpolarization-activated cyclic nucleotide-gated channels in rat pancreatic beta cells.

Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13.

A study on the mechanical properties of beagle femoral head using the digital speckle correlation method.

Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus (A/H1N1)?

Evolutionary trends of A(H1N1) influenza virus hemagglutinin since 1918.

[Detection of molecular markers of amantadine resistance in swine influenza viruses by pyrosequencing].

Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement.

A new method for the reconstruction of micro- and nanoscale planar periodic structures.

Insulin treatment and high-fat diet feeding reduces the expression of three Tcf genes in rodent pancreas.

Novel GLP-1 fusion chimera as potent long acting GLP-1 receptor agonist.

A site-specific genomic integration strategy for sustained expression of glucagon-like peptide-1 in mouse muscle for controlling energy homeostasis.

The role of insulin signaling in the development of β-cell dysfunction and diabetes.

Expression analysis of Djsix-1 gene during regeneration of planarian eyespots.

Purification and characterization of a CkTLP protein from Cynanchum komarovii seeds that confers antifungal activity.

Identification of a UDP-glucose pyrophosphorylase from cotton (Gossypium hirsutum L.) involved in cellulose biosynthesis in Arabidopsis thaliana.

Measurement of interfacial toughness of metal film wire and polymer membrane through electricity induced buckling method.

Diagnostic performance of magnetic resonance cholangiopancreatography in malignant obstructive jaundice.

GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes.

Immunity against a therapeutic xenoprotein/Fc construct delivered by gene transfer is reduced through binding to the inhibitory receptor FcγRIIb.

Eight genes expression patterns during visual system regeneration in Dugesia japonica.

[Determination of 88 pesticide residues in tea using gas chromatography-tandem mass spectrometry].

Exploring weak, transient protein--protein interactions in crowded in vivo environments by in-cell nuclear magnetic resonance spectroscopy.

GABA coordinates with insulin in regulating secretory function in pancreatic INS-1 β-cells.

Mortality of dementia and its major subtypes in urban and rural communities of Beijing.

Three-directional structural characterization of hexagonal packed nanoparticles by hexagonal digital moiré method.

Genome-wide polycomb target gene prediction in Drosophila melanogaster.

Community annotation and bioinformatics workforce development in concert--Little Skate Genome Annotation Workshops and Jamborees.

Purification, characterization of a CkChn134 protein from Cynanchum komarovii seeds and synergistic effect with CkTLP against Verticillium dahliae.

Nodal induces apoptosis through activation of the ALK7 signaling pathway in pancreatic INS-1 β-cells.

Dynamic evolution of bz orthologous regions in the Andropogoneae and other grasses.

The protective effect of peroxiredoxin II on oxidative stress induced apoptosis in pancreatic β-cells.

Insulin detemir enhances proglucagon gene expression in the intestinal L cells via stimulating β-catenin and CREB activities.

The Wnt signaling pathway effector TCF7L2 controls gut and brain proglucagon gene expression and glucose homeostasis.

Complete genome sequence of a Peste des petits ruminants virus recovered from wild bharal in Tibet, China.

Palmitate causes endoplasmic reticulum stress and apoptosis in human mesenchymal stem cells: prevention by AMPK activator.

Post-transplant monitoring of soluble CD30 level as predictor of graft outcome: a single center experience from China.

Jejunal tube feeding and pancreatoduodenectomy.

The eFIP system for text mining of protein interaction networks of phosphorylated proteins.

Intra-islet glucagon secretion and action in the regulation of glucose homeostasis.

Formation of secondary Moiré patterns for characterization of nanoporous alumina structures in multiple domains with different orientations.

A new atlas localization approach for subthalamic nucleus utilizing Chinese visible human head datasets.

β-cell proliferation is associated with increased A-type γ-aminobutyric acid receptor expression in pancreatectomized mice.

GLP-1(28-36) improves β-cell mass and glucose disposal in streptozotocin-induced diabetic mice and activates cAMP/PKA/β-catenin signaling in β-cells in vitro.

Expression, purification and preliminary characterization of glucagon receptor extracellular domain.

Structural basis of actin filament nucleation by tandem W domains.

Enhanced mechanical strength and electrical conductivity of carbon-nanotube/TiC hybrid fibers.

Characterization of a novel chitinase, DkChi, from Dendrolimus kikuchii nucleopolyhedrovirus.

GABA protects human islet cells against the deleterious effects of immunosuppressive drugs and exerts immunoinhibitory effects alone.

Gene tagging with engineered Ds elements in maize.

Structural basis for the divergent evolution of influenza B virus hemagglutinin.

Transcription factors and genetic circuits orchestrating the complex, multilayered response of Clostridium acetobutylicum to butanol and butyrate stress.

Simultaneous determination of thiophanate-methyl and its metabolite carbendazim in tea using isotope dilution ultra performance liquid chromatography-tandem mass spectrometry.

Structural insights into the membrane fusion mechanism mediated by influenza virus hemagglutinin.

Spot moiré fringes: determination of domain boundaries and structural parameters in ordered nanoporous structures.

Severe intra-abdominal bleeding leading to hemorrhagic shock, rectal perforation, and bilateral hydrothorax after stapling procedure for prolapsed hemorrhoids (PPH): is the transanal drainage feasible in this situation? : report of a case and a successful experience.

The roles of hemagglutinin Phe-95 in receptor binding and pathogenicity of influenza B virus.

Severe intra-abdominal bleeding leading to hemorrhagic shock, rectal perforation and bilateral hydrothorax after stapling procedure for prolapsed hemorrhoids.

Iridocorneal endothelial syndrome in a Chinese child.

Formation of three-way scanning electron microscope moiré on micro/nanostructures.

Development of a novel electrochemical DNA biosensor based on elongated hexagonal-pyramid CdS and poly-isonicotinic acid composite film.

Loop-mediated isothermal amplification (LAMP) method for detection of genetically modified maize T25.

Modulation of GLUT4 expression by oral administration of Mg(2+) to control sugar levels in STZ-induced diabetic rats.

Metabolic profiling of somatic tissues from Monochamus alternatus (Coleoptera: Cerambycidae) reveals effects of irradiation on metabolism.

The anorexic effect of Ex4/Fc through GLP-1 receptor activation in high-fat diet fed mice.

The stem cell factor/Kit signalling pathway regulates mitochondrial function and energy expenditure.

Highly dispersible and stable copper terephthalate metal-organic framework-graphene oxide nanocomposite for an electrochemical sensing application.

GABA promotes human β-cell proliferation and modulates glucose homeostasis.

Order and disorder control the functional rearrangement of influenza hemagglutinin.

GABA protects pancreatic beta cells against apoptosis by increasing SIRT1 expression and activity.

miRNA-302 facilitates reprogramming of human adult hepatocytes into pancreatic islets-like cells in combination with a chemical defined media.

Complete Genome Sequence of a Novel Variant Strain of Peste des Petits Ruminants Virus, China/XJYL/2013.

Monitoring and risk assessment of 74 pesticide residues in Pu-erh tea produced in Yunnan, China.

Enantioselective Dissipation of Acephate and Its Metabolite, Methamidophos, during Tea Cultivation, Manufacturing, and Infusion.

GABAergic system in the endocrine pancreas: a new target for diabetes treatment.

Loss of conserved Gsdma3 self-regulation causes autophagy and cell death.

Liver-specific deletion of Ppp2cα enhances glucose metabolism and insulin sensitivity.

Vascularization of repaired limb bone defects using chitosan-β-tricalcium phosphate composite as a tissue engineering bone scaffold.

Hydroxycamptothecin-induced apoptotic gene expression profiling by PCR array in human Tenon's capsule fibroblasts.

Structural and Functional Studies of Influenza Virus A/H6 Hemagglutinin.

Immunological GABAergic interactions and therapeutic applications in autoimmune diseases.

Ontogenic expression profiles and oxaliplatin regulation of leptin expression in mice dorsal root ganglion.

RLIMS-P 2.0: A Generalizable Rule-Based Information Extraction System for Literature Mining of Protein Phosphorylation Information.

Mechanisms of leiomodin 2-mediated regulation of actin filament in muscle cells.

Deformable complex network for refining low-resolution X-ray structures.

Study of GABA in Healthy Volunteers: Pharmacokinetics and Pharmacodynamics.

Relationships of related genetic polymorphisms and individualized medication of tacrolimus in patients with renal transplantation.

PP2A regulates kinetochore-microtubule attachment during meiosis I in oocyte.

Effects of interleukin 6 and tumor necrosis factor-α on the proliferation of porcine theca interna cells: Possible role of these cytokines in the pathogenesis of polycystic ovary syndrome.

MicroRNA-mediated epigenetic targeting of Survivin significantly enhances the antitumor activity of paclitaxel against non-small cell lung cancer.

Neuromuscular interaction is required for neurotrophins-mediated locomotor recovery following treadmill training in rat spinal cord injury.

Rapid detection of lineage IV peste des petits ruminants virus by real-time RT-PCR.

Quantification of 18 amino acids in human plasma: application in renal transplant patient plasma by targeted UHPLC-MS/MS.

Gastric Bypass Surgery Reverses Diabetic Phenotypes in Bdnf-Deficient Mice.

Decorated TiO2 Nanoparticles with La and Ag Elements to Improve Photocatalytic Activity Under Visible Light for the Degradation of MO.

Glucagon Like Peptide-1 Promotes Adipocyte Differentiation via the Wnt4 Mediated Sequestering of Beta-Catenin.

Lowered pH Leads to Fusion Peptide Release and a Highly Dynamic Intermediate of Influenza Hemagglutinin.

Exogenous kallikrein protects against diabetic nephropathy.

Overview of the interactive task in BioCreative V.

Digital sampling Moiré as a substitute for microscope scanning Moiré for high-sensitivity and full-field deformation measurement at micron/nano scales.

Three novel species of coccoid green algae within the Watanabea clade (Trebouxiophyceae, Chlorophyta).

Reversal effect of ouabain on multidrug resistance in esophageal carcinoma EC109/CDDP cells by inhibiting the translocation of Wnt/β-catenin into the nucleus.

Experimental Study on Damage Detection in Timber Specimens Based on an Electromechanical Impedance Technique and RMSD-Based Mahalanobis Distance.

Celecoxib alleviates oxaliplatin-induced hyperalgesia through inhibition of spinal ERK1/2 signaling.

Protein Ontology (PRO): enhancing and scaling up the representation of protein entities.

Aminoglycoside-based novel probes for bacterial diagnostic and therapeutic applications.

Organochlorine pesticides in tree bark and human hair in Yunnan Province, China: Concentrations, distributions and exposure pathway.

Activated Microglia Induce Bone Marrow Mesenchymal Stem Cells to Produce Glial Cell-Derived Neurotrophic Factor and Protect Neurons Against Oxygen-Glucose Deprivation Injury.

Analysis of Protein Phosphorylation and Its Functional Impact on Protein-Protein Interactions via Text Mining of the Scientific Literature.

Cardiovascular Benefits of Native GLP-1 and its Metabolites: An Indicator for GLP-1-Therapy Strategies.

Current halogenated flame retardant concentrations in serum from residents of Shandong Province, China, and temporal changes in the concentrations.

Organochlorine pesticide concentrations in pooled serum of people in different age groups from five Chinese cities.

JMJD3 is crucial for female AVPV RIP-Cre neuron controlled kisspeptin-estrogen feedback loop and reproductive function.

[Hypoxia-inducible factor-1α and CD133 predicts pathological complete response and survival for locally advanced rectal cancer patients after neoadjuvant chemoradiotherapy].

Protein therapy using MafA fused to a polyarginine transduction domain attenuates glucose levels of streptozotocin‑induced diabetic mice.

Impact of old age on resectable colorectal cancer outcomes.

p.L105Vfs mutation in a family with thymic neuroendocrine tumor combined with MEN1: a case report.

Poorer prognosis for neuroendocrine carcinoma than signet ring cell cancer of the colon and rectum (CRC-NEC): a propensity score matching analysis of patients from the Surveillance, Epidemiology, and End Results (SEER) database.

A Case Report: Cutaneous Metastasis of Advanced Rectal Cancer with BRAF Mutation.

Competing Nomogram for Late-Period Breast Cancer-Specific Death in Patients with Early-Stage Hormone Receptor-Positive Breast Cancer.

Estrogen receptor-negative/progesterone receptor-positive and her-2-negative breast cancer might no longer be classified as hormone receptor-positive breast cancer.