Sophie Williams

Initial sequencing and comparative analysis of the mouse genome.

Metal-on-metal bearing wear with different swing phase loads.

Comparative wear under different conditions of surface-engineered metal-on-metal bearings for total hip arthroplasty.

Quinazolinethiones and quinazolinediones, novel inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships.

Effect of swing phase load on metal-on-metal hip lubrication, friction and wear.

Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors.

Low molecular weight indole fragments as IMPDH inhibitors.

Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships.

Friction of total hip replacements with different bearings and loading conditions.

Characterisation of wear particles produced by metal on metal and ceramic on metal hip prostheses under standard and microseparation simulation.

The influence of clearance on friction, lubrication and squeaking in large diameter metal-on-metal hip replacements.

Development of CXCR3 antagonists. Part 3: Tropenyl and homotropenyl-piperidine urea derivatives.

Development of CXCR3 antagonists. Part 4: discovery of 2-amino-(4-tropinyl)quinolines.

The 2007 Otto Aufranc Award. Ceramic-on-metal hip arthroplasties: a comparative in vitro and in vivo study.

Long-term radiographic assessment of cemented polyethylene acetabular cups.

Effect of bearing size on the long-term wear, wear debris, and ion levels of large diameter metal-on-metal hip replacements-An in vitro study.

Tribology and wear of metal-on-metal hip prostheses: influence of cup angle and head position.

Surface engineering: a low wearing solution for metal-on-metal hip surface replacements.

High cup angle and microseparation increase the wear of hip surface replacements.

Mu2-alkyne dicobalt(0)hexacarbonyl complexes as carbon monoxide-releasing molecules (CO-RMs): probing the release mechanism.

Subsurface changes of a MoM hip implant below different contact zones.

Synthesis and in vivo evaluation of 3-substituted gababutins.

Synthesis and in vivo evaluation of 3,4-disubstituted gababutins.

Synthesis and in vivo evaluation of bicyclic gababutins.

Atypical squamous cells, cannot exclude high grade squamous intraepithelial (ASC-H) in HIV-positive women.

Effect of cup inclination angle during microseparation and rim loading on the wear of BIOLOX® delta ceramic-on-ceramic total hip replacement.

Bacterial vaginosis as a risk factor for high-grade cervical lesions and cancer in HIV-seropositive women.

MACiE: exploring the diversity of biochemical reactions.

Training programmes can change behaviour and encourage the cultivation of over-harvested plant species.

Wear of ceramic-on-carbon fiber-reinforced poly-ether ether ketone hip replacements.

Squeaking hip arthroplasties: a tribological phenomenon.

Changes in attributions as a consequence of training for challenging and complex behaviour for carers of people with learning disabilities: a systematic review.

In vitro comparison of fixed- and mobile meniscal-bearing unicondylar knee arthroplasties: effect of design, kinematics, and condylar liftoff.

Highly active antiretroviral therapy and cervical dysplasia in HIV-positive women in South Africa.

Comparison of human and animal femoral head chondral properties and geometries.

Australasian respiratory and emergency physicians do not use the pneumonia severity index in community-acquired pneumonia.

Regional cartilage properties of three quadruped tibiofemoral joints used in musculoskeletal research studies.

The effect of cup orientation and coverage on contact mechanics and range of motion of metal-on-metal hip resurfacing arthroplasty.

Effect of femoral head size on the wear of metal on metal bearings in total hip replacements under adverse edge-loading conditions.

Validation of cervical cancer screening methods in HIV positive women from Johannesburg South Africa.

(iv) Enhancing the safety and reliability of joint replacement implants.

(v) Simulation and measurement of wear in metal-on-metal bearings in vitro- understanding the reasons for increased wear.

Comparison of ceramic-on-metal and metal-on-metal hip prostheses under adverse conditions.

Completing the audit cycle improves surgical standards in lung cancer. Why do some patients still not receive the best care?

Wear of surface-engineered metal-on-metal bearings for hip prostheses under adverse conditions with the head loading on the rim of the cup.

Wear of 36-mm BIOLOX(R) delta ceramic-on-ceramic bearing in total hip replacements under edge loading conditions.

Effect of head contact on the rim of the cup on the offset loading and torque in hip joint replacement.

Effect of clearance on cartilage tribology in hip hemi-arthroplasty.

Injectable and oral contraception and the incidence and progression of cervical disease in HIV-infected women in South Africa.

Goodnight book: sleep consolidation improves word learning via storybooks.

Experimental validation of a new biphasic model of the contact mechanics of the porcine hip.

How getting noticed helps getting on: successful attention capture doubles children's cooperative play.

Evaluation of a cervicography-based program to ensure quality of visual inspection of the cervix in HIV-infected women in Johannesburg, South Africa.

A snapshot of the lives of women with polycystic ovary syndrome: A photovoice investigation.

Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency.

Effect of microseparation on contact mechanics in metal-on-metal hip replacements-A finite element analysis.

Paradigms and progress in conservation science.

Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates.

Exploring Carers' Judgements of Responsibility and Control in Response to the Challenging Behaviour of People with Intellectual Disabilities.

The cannabis conundrum: Thinking outside the THC box.

Development and characterisation of a decellularised bovine osteochondral biomaterial for cartilage repair.

Retrospective Cohort Study to Assess Outcomes, Cost-Effectiveness, and Patient Satisfaction in Primary Vaginal Ovarian Cystectomy versus the Laparoscopic Approach.

Seizure control by decanoic acid through direct AMPA receptor inhibition.

Osteoarthritic bone marrow lesions almost exclusively colocate with denuded cartilage: a 3D study using data from the Osteoarthritis Initiative.

Modulating carnitine levels by targeting its biosynthesis pathway - selective inhibition of γ-butyrobetaine hydroxylase.

Prospective One Year Follow Up of HIV Infected Women Screened for Cervical Cancer Using Visual Inspection with Acetic Acid, Cytology and Human Papillomavirus Testing in Johannesburg South Africa.

The 2015 advanced life support guidelines: a summary and evidence for the updates.

Whole-pattern fitting technique in serial femtosecond nanocrystallography.

The influence of the representation of collagen fibre organisation on the cartilage contact mechanics of the hip joint.

Influence of hip joint simulator design and mechanics on the wear and creep of metal-on-polyethylene bearings.

The Effect of Sleep on Children's Word Retention and Generalization.

X-ray laser-induced electron dynamics observed by femtosecond diffraction from nanocrystals of Buckminsterfullerene.

'Everything's from the inside out with PCOS': Exploring women's experiences of living with polycystic ovary syndrome and co-morbidities through Skype™ interviews.

Three-dimensional assessment of impingement risk in geometrically parameterised hips compared with clinical measures.

Predicting surgical outcome in patients with glioblastoma multiforme using pre-operative magnetic resonance imaging: development and preliminary validation of a grading system.

Controlling the Nanoscale Patterning of AuNPs on Silicon Surfaces.

Evaluation of a new methodology to simulate damage and wear of polyethylene hip replacements subjected to edge loading in hip simulator testing.