Renaud Louis

Matrix metalloproteinase-9 deficiency impairs cellular infiltration and bronchial hyperresponsiveness during allergen-induced airway inflammation.

CD40 engagement enhances eosinophil survival through induction of cellular inhibitor of apoptosis protein 2 expression: Possible involvement in allergic inflammation.

Matrix metalloproteinase-9, but not tissue inhibitor of matrix metalloproteinase-1, increases in the sputum from allergic asthmatic patients after allergen challenge.

Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases mRNA transcripts in the bronchial secretions of asthmatics.

Repeated cadmium nebulizations induce pulmonary MMP-2 and MMP-9 production and emphysema in rats.

Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation.

18F-FDG PET imaging in assessing exudative pleural effusions.

Expression of ADAMs and their inhibitors in sputum from patients with asthma.

Diagnostic value of interleukine-6, transforming growth factor-beta 1 and vascular endothelial growth factor in malignant pleural effusions.

Prognostic value of metabolic imaging in non-small cell lung cancers with neoplasic pleural effusion.

Biomarker discovery in asthma-related inflammation and remodeling.

Leukotriene B4 contributes to exhaled breath condensate and sputum neutrophil chemotaxis in COPD.

Macrophage-derived exosomes attenuate fibrosis in airway epithelial cells through delivery of antifibrotic miR-142-3p.

Mouse models of asthma: a comparison between C57BL/6 and BALB/c strains regarding bronchial responsiveness, inflammation, and cytokine production.

Matrix metalloproteinase-19 deficiency promotes tenascin-C accumulation and allergen-induced airway inflammation.

Exhaled nitric oxide thresholds associated with a sputum eosinophil count ≥3% in a cohort of unselected patients with asthma.

Sirtuin 1 promotes Th2 responses and airway allergy by repressing peroxisome proliferator-activated receptor-γ activity in dendritic cells.

Corticosteroids: still at the frontline in asthma treatment?

Diagnostic value of neurotrophin expression in malignant pleural effusions.

Increased glutaredoxin-1 and decreased protein S-glutathionylation in sputum of asthmatics.

Distribution of sputum cellular phenotype in a large asthma cohort: predicting factors for eosinophilic vs neutrophilic inflammation.

Importance of concomitant local and systemic eosinophilia in uncontrolled asthma.

Impact of cotransplantation of mesenchymal stem cells on lung function after unrelated allogeneic hematopoietic stem cell transplantation following non-myeloablative conditioning.

Exertional hypoxemia in stable COPD is common and predicted by circulating proadrenomedullin.

Increased of exhaled breath condensate neutrophil chemotaxis in acute exacerbation of COPD.

Importance of concomitant local and systemic eosinophilia in uncontrolled asthma.

Bronchial thermoplasty: a new therapeutic option for the treatment of severe, uncontrolled asthma in adults.

Improvement of malignant pleural mesothelioma immunotherapy by epigenetic modulators.

Mite allergen-specific IgE is detectable in bronchial secretions of patients with nonatopic asthma and correlates with mucosal expression of periostin.

Mannose-binding lectin protein and its association to clinical outcomes in COPD: a longitudinal study.

Therapy with proton-pump inhibitors for gastroesophageal reflux disease does not reduce the risk for severe exacerbations in COPD.

Detailed analysis of sputum and systemic inflammation in asthma phenotypes: are paucigranulocytic asthmatics really non-inflammatory?

Prognostic assessment in COPD without lung function: the B-AE-D indices.

Asthma inflammatory phenotypes show differential microRNA expression in sputum.

Lung-resident eosinophils represent a distinct regulatory eosinophil subset.

Systemic Biomarkers of Collagen and Elastin Turnover Are Associated With Clinically Relevant Outcomes in COPD.

A historical perspective: Are inhaled corticoids sufficient to control asthma?

A Belgian survey on the diagnosis of asthma-COPD overlap syndrome.

Asthma Control and Sputum Eosinophils: A Longitudinal Study in Daily Practice.

Increased production of TGF-β1 from sputum cells of COPD: Relationship with airway obstruction.

Is it possible to claim or refute sputum eosinophils ≥ 3% in asthmatics with sufficient accuracy using biomarkers?

Precision medicine in airway diseases: moving to clinical practice.

Treatment with long acting muscarinic antagonists stimulates serum levels of irisin in patients with COPD.

Effectiveness of inhaled corticosteroids in real life on clinical outcomes, sputum cells and systemic inflammation in asthmatics: a retrospective cohort study in a secondary care centre.

The Lung Microbiome in Idiopathic Pulmonary Fibrosis: A Promising Approach for Targeted Therapies.

Intensified Therapy with Inhaled Corticosteroids and Long-Acting β-Agonists at the Onset of Upper Respiratory Tract Infection to Prevent Chronic Obstructive Pulmonary Disease Exacerbations. A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial.

IFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes.

Collagen Degradation and Formation Are Elevated in Exacerbated COPD Compared With Stable Disease.

Rhinology Future Debates 2017 by EUFOREA: Novel treatments and surgical solutions in rhinology.

Tumor cells may circulate in medullary thyroid cancer patients independently of serum calcitonin.

Sputum exosomes: promising biomarkers for idiopathic pulmonary fibrosis.

Serum levels of hyaluronic acid are associated with COPD severity and predict survival.

Exhaled Volatile Organic Compounds Are Able to Discriminate between Neutrophilic and Eosinophilic Asthma.

Increase in blood eosinophils during follow-up is associated with lung function decline in adult asthma.

Biomarkers in systemic sclerosis-associated interstitial lung disease: review of the literature.

Time-course of upper respiratory tract viral infection and COPD exacerbation.

Personalised medicine: are we ready?

Bronchial thermoplasty decreases airway remodelling by blocking epithelium-derived heat shock protein-60 secretion and protein arginine methyltransferase-1 in fibroblasts.

Exosomal miRNAs in Lung Diseases: From Biologic Function to Therapeutic Targets.

Inhibition of EZH2 methyltransferase decreases immunoediting of mesothelioma cells by autologous macrophages through a PD-1-dependent mechanism.

Bronchodilation Test with Inhaled Salbutamol Versus Bronchial Methacholine Challenge to Make an Asthma Diagnosis: Do They Provide the Same Information?

Suitable reference genes determination for real-time PCR using induced sputum samples.

Severe asthma: oral corticosteroid alternatives and the need for optimal referral pathways.

Real-word experience with mepolizumab: Does it deliver what it has promised?

Mepolizumab for allergic bronchopulmonary aspergillosis: Report of 20 cases from the Belgian Severe Asthma Registry and review of the literature.

Exosomal Long Non-Coding RNAs in Lung Diseases.

Comparison of the effect of chemically and biologically induced inflammation on the volatile metabolite production of lung epithelial cells by GC×GC-TOFMS.

Effect of the Use of Intranasal Spray of Essential Oils in Patients with Perennial Allergic Rhinitis: A Prospective Study.

Multimodal combination of GC × GC-HRTOFMS and SIFT-MS for asthma phenotyping using exhaled breath.

Comprehensive Cluster Analysis for COPD Including Systemic and Airway Inflammatory Markers.