Laboratory of Genetics
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Biopiracy: distrust widens the rich-poor divide.
Molecular therapy : the journal of the American Society of Gene Therapy Feb, 2002 | Pubmed ID: 11829514
Adeno-associated virus effectively mediates conditional gene modification in the brain.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2002 | Pubmed ID: 11842206
Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2002 | Pubmed ID: 11854510
Effect of adenovirus-mediated overexpression of follistatin and extracellular domain of activin receptor type II on gonadotropin secretion in vitro and in vivo.
Endocrinology Mar, 2002 | Pubmed ID: 11861519
A gene therapy institute for NIH?
Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2002 | Pubmed ID: 11863406
Censorship of scientific publications: a bad idea.
Molecular therapy : the journal of the American Society of Gene Therapy Apr, 2002 | Pubmed ID: 11945057
Politics and AIDS: a bad mix.
Molecular therapy : the journal of the American Society of Gene Therapy May, 2002 | Pubmed ID: 11991737
Do not ban therapeutic cloning.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2002 | Pubmed ID: 12027544
Restoration of spermatogenesis by lentiviral gene transfer: offspring from infertile mice.
Proceedings of the National Academy of Sciences of the United States of America May, 2002 | Pubmed ID: 12032316
Hypothesis-driven science.
Molecular therapy : the journal of the American Society of Gene Therapy Jul, 2002 | Pubmed ID: 12095295
Biodistribution and toxicity studies of VSVG-pseudotyped lentiviral vector after intravenous administration in mice with the observation of in vivo transduction of bone marrow.
Molecular therapy : the journal of the American Society of Gene Therapy Jul, 2002 | Pubmed ID: 12095299
Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2002 | Pubmed ID: 12231171
Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors.
Blood Oct, 2002 | Pubmed ID: 12351379
Gene therapy with viral vectors.
Annual review of pharmacology and toxicology , 2003 | Pubmed ID: 12359866
NF-kappaB regulation in the immune system.
Nature reviews. Immunology Oct, 2002 | Pubmed ID: 12360211
Politics and scientific publishing: noli me tangere.
Molecular therapy : the journal of the American Society of Gene Therapy Oct, 2002 | Pubmed ID: 12377181
Success and setback: another adverse event.
Molecular therapy : the journal of the American Society of Gene Therapy Nov, 2002 | Pubmed ID: 12409253
Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein.
The Journal of biological chemistry Feb, 2003 | Pubmed ID: 12431996
Making the promise a reality.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2002 | Pubmed ID: 12498763
Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2003 | Pubmed ID: 12547912
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2003 | Pubmed ID: 12552109
A voluntary moratorium?
Molecular therapy : the journal of the American Society of Gene Therapy Feb, 2003 | Pubmed ID: 12638540
Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2003 | Pubmed ID: 12657655
Efficient production of human FVIII in hemophilic mice using lentiviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy May, 2003 | Pubmed ID: 12718905
The DNA helix at 50.
Molecular therapy : the journal of the American Society of Gene Therapy Apr, 2003 | Pubmed ID: 12731541
Good-bye Dolly.
Molecular therapy : the journal of the American Society of Gene Therapy May, 2003 | Pubmed ID: 12755157
BRCA2 cooperates with histone acetyltransferases in androgen receptor-mediated transcription.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2003 | Pubmed ID: 12756300
SARS: fear of global pandemic.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2003 | Pubmed ID: 12788644
Illiteracy, ignorance, intolerance=terrorism.
Molecular therapy : the journal of the American Society of Gene Therapy Jul, 2003 | Pubmed ID: 12872760
Stem cells at the dawn of the 21st century.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2003 | Pubmed ID: 12915737
Little evidence of bone marrow-derived hepatocytes in the replacement of injured liver.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2003 | Pubmed ID: 12920184
Generation of transgenic mice using lentiviral vectors: a novel preclinical assessment of lentiviral vectors for gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy Oct, 2003 | Pubmed ID: 14529840
Fraud and deception in science.
Molecular therapy : the journal of the American Society of Gene Therapy Oct, 2003 | Pubmed ID: 14565217
Adenovirus-mediated overexpression of follistatin enlarges intact liver of adult rats.
Hepatology (Baltimore, Md.) Nov, 2003 | Pubmed ID: 14578849
IkappaB kinase-independent IkappaBalpha degradation pathway: functional NF-kappaB activity and implications for cancer therapy.
Molecular and cellular biology Nov, 2003 | Pubmed ID: 14585967
AIDS: no end in sight.
Molecular therapy : the journal of the American Society of Gene Therapy Feb, 2004 | Pubmed ID: 14971375
Silence of the genes.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2004 | Pubmed ID: 15067116
Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy Apr, 2004 | Pubmed ID: 15093185
CRE recombinase-inducible RNA interference mediated by lentiviral vectors.
Proceedings of the National Academy of Sciences of the United States of America May, 2004 | Pubmed ID: 15123829
Stem cell politics get dirty.
Molecular therapy : the journal of the American Society of Gene Therapy May, 2004 | Pubmed ID: 15143773
Characterization of NF-kappa B/I kappa B proteins in zebra fish and their involvement in notochord development.
Molecular and cellular biology Jun, 2004 | Pubmed ID: 15169890
Visa crisis hurts U.S. science.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2004 | Pubmed ID: 15194044
Activation of transcription factor NF-kappaB requires ELKS, an IkappaB kinase regulatory subunit.
Science (New York, N.Y.) Jun, 2004 | Pubmed ID: 15218148
Agbiotech: success depends on trust.
Molecular therapy : the journal of the American Society of Gene Therapy Jul, 2004 | Pubmed ID: 15233936
Musings for young scientists.
Molecular therapy : the journal of the American Society of Gene Therapy Aug, 2004 | Pubmed ID: 15294164
Doping, gene transfer and sport.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2004 | Pubmed ID: 15336640
The knockout mouse project.
Nature genetics Sep, 2004 | Pubmed ID: 15340423
A role for bone marrow-derived cells in the vasculature of noninjured CNS.
Blood Mar, 2005 | Pubmed ID: 15572598
Development of ecdysone-regulated lentiviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy Jan, 2005 | Pubmed ID: 15585415
Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy.
Blood Apr, 2005 | Pubmed ID: 15637142
Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2005 | Pubmed ID: 15657137
Interview with Dr Verma.
Gene therapy Jun, 2005 | Pubmed ID: 15674396
Inflammation-associated cancer: NF-kappaB is the lynchpin.
Trends in immunology Jun, 2005 | Pubmed ID: 15922948
Gene therapy: twenty-first century medicine.
Annual review of biochemistry , 2005 | Pubmed ID: 15952901
Zebrafish IkappaB kinase 1 negatively regulates NF-kappaB activity.
Current biology : CB Jul, 2005 | Pubmed ID: 16051172
Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1).
Proceedings of the National Academy of Sciences of the United States of America Aug, 2005 | Pubmed ID: 16116086
Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model.
Nature neuroscience Oct, 2005 | Pubmed ID: 16136043
Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity.
Nature cell biology Sep, 2005 | Pubmed ID: 16136188
From one experiment to the next.
BioTechniques Oct, 2005 | Pubmed ID: 16235552
Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2005 | Pubmed ID: 16239341
Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice.
Nature Dec, 2005 | Pubmed ID: 16244648
Choroidal neovascularization in transgenic mice expressing prokineticin 1: an animal model for age-related macular degeneration.
Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2006 | Pubmed ID: 16263331
Bioscience in India: times are changing.
Cell Dec, 2005 | Pubmed ID: 16325565
Lentiviral short hairpin ribonucleic acid-mediated knockdown of GLUT4 in 3T3-L1 adipocytes.
Endocrinology May, 2006 | Pubmed ID: 16497797
Gene therapy: therapeutic gene causing lymphoma.
Nature Apr, 2006 | Pubmed ID: 16641981
Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival.
Cancer cell Sep, 2006 | Pubmed ID: 16959613
A fourth IkappaB protein within the NF-kappaB signaling module.
Cell Jan, 2007 | Pubmed ID: 17254973
Inflammatory tales of liver cancer.
Cancer cell Feb, 2007 | Pubmed ID: 17292819
Efficient transgenic rat production by a lentiviral vector.
American journal of physiology. Heart and circulatory physiology Jul, 2007 | Pubmed ID: 17322424
Suppression of PPAR-gamma attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes.
American journal of physiology. Endocrinology and metabolism Jul, 2007 | Pubmed ID: 17389706
Design and cloning of lentiviral vectors expressing small interfering RNAs.
Nature protocols , 2006 | Pubmed ID: 17406238
Production and purification of lentiviral vectors.
Nature protocols , 2006 | Pubmed ID: 17406239
Rapid generation of knockdown transgenic mice by silencing lentiviral vectors.
Nature protocols , 2006 | Pubmed ID: 17406246
Neprilysin protects neurons against Abeta peptide toxicity.
Brain research Jun, 2007 | Pubmed ID: 17459354
Targeted delivery of proteins across the blood-brain barrier.
Proceedings of the National Academy of Sciences of the United States of America May, 2007 | Pubmed ID: 17463083
Intercellular coupling confers robustness against mutations in the SCN circadian clock network.
Cell May, 2007 | Pubmed ID: 17482552
A role for IkappaB kinase 2 in bipolar spindle assembly.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2007 | Pubmed ID: 17939994
Repopulation of adult and neonatal mice with human hepatocytes: a chimeric animal model.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2007 | Pubmed ID: 18077355
Reciprocity between phase shifts and amplitude changes in the mammalian circadian clock.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2007 | Pubmed ID: 18077393
Sustained suppression of Bcr-Abl-driven lymphoid leukemia by microRNA mimics.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2007 | Pubmed ID: 18079287
Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease.
The American journal of pathology May, 2008 | Pubmed ID: 18403590
Phosphorylation of SNAP-23 by IkappaB kinase 2 regulates mast cell degranulation.
Cell Aug, 2008 | Pubmed ID: 18692471
Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice.
BMC neuroscience , 2008 | Pubmed ID: 19014502
Applications of lentiviral vectors for shRNA delivery and transgenesis.
Current gene therapy Dec, 2008 | Pubmed ID: 19075631
Development of a novel mouse glioma model using lentiviral vectors.
Nature medicine Jan, 2009 | Pubmed ID: 19122659
Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration.
BMC biology , 2009 | Pubmed ID: 19144100
Genic regions of a large salamander genome contain long introns and novel genes.
BMC genomics , 2009 | Pubmed ID: 19144141
Phosphorylation of p53 by IkappaB kinase 2 promotes its degradation by beta-TrCP.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2009 | Pubmed ID: 19196987
Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells.
Nature Jul, 2009 | Pubmed ID: 19483674
Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice.
Cell metabolism Nov, 2009 | Pubmed ID: 19883619
CtIP links DNA double-strand break sensing to resection.
Molecular cell Dec, 2009 | Pubmed ID: 20064462
Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment.
The Journal of clinical investigation Mar, 2010 | Pubmed ID: 20179355
Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression.
Nature cell biology Aug, 2010 | Pubmed ID: 20622870
Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells.
Atherosclerosis Nov, 2010 | Pubmed ID: 20688330
A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity.
Current biology : CB Jan, 2011 | Pubmed ID: 21167714
Transdifferentiation of glioblastoma cells into vascular endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2011 | Pubmed ID: 21262804
Peripheral delivery of a CNS targeted, metalo-protease reduces aβ toxicity in a mouse model of Alzheimer's disease.
PloS one , 2011 | Pubmed ID: 21304989
Design and Cloning of an shRNA into a Lentiviral Silencing Vector: Version A.
CSH protocols , 2008 | Pubmed ID: 21356884
Design and Cloning of an shRNA into a Lentiviral Silencing Vector: Version B.
CSH protocols , 2008 | Pubmed ID: 21356885
Knockdown transgenic mice generated by silencing lentiviral vectors: zona pellucida removal and subzonal injection methods.
CSH protocols , 2007 | Pubmed ID: 21357087
Human xeno-autoantibodies against a non-human sialic acid serve as novel serum biomarkers and immunotherapeutics in cancer.
Cancer research May, 2011 | Pubmed ID: 21505105
Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines.
Stem cells (Dayton, Ohio) Jul, 2011 | Pubmed ID: 21544903
BRCA1 tumour suppression occurs via heterochromatin-mediated silencing.
Nature Sep, 2011 | Pubmed ID: 21901007
Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2011 | Pubmed ID: 21949408
Antiapoptotic protein Lifeguard is required for survival and maintenance of Purkinje and granular cells.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2011 | Pubmed ID: 21957071
Tumor suppressor p53 functions as a negative regulator in IgE-mediated mast cell activation.
PloS one , 2011 | Pubmed ID: 21966524
Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2011 | Pubmed ID: 21969599
QnAs with Inder M. Verma. Interview by Prashant Nair.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2011 | Pubmed ID: 22135469
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
Nature cell biology Feb, 2012 | Pubmed ID: 22327365
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