Division of Newborn Medicine,
Department of Pediatrics,
Division of Newborn Medicine, Department of Pediatrics
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DNA palindromes with a modest arm length of greater, similar 20 base pairs are a significant target for recombinant adeno-associated virus vector integration in the liver, muscles, and heart in mice.
Journal of virology Oct, 2007 | Pubmed ID: 17686840
The role of DNA-PKcs and artemis in opening viral DNA hairpin termini in various tissues in mice.
Journal of virology Oct, 2007 | Pubmed ID: 17686847
Extracellular high mobility group box-1 (HMGB1) inhibits enterocyte migration via activation of Toll-like receptor-4 and increased cell-matrix adhesiveness.
The Journal of biological chemistry Feb, 2010 | Pubmed ID: 20007974
Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2012 | Pubmed ID: 22733781
Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice.
Gastroenterology Sep, 2012 | Pubmed ID: 22796522
Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis.
The Journal of biological chemistry Oct, 2012 | Pubmed ID: 22955282
A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2013 | Pubmed ID: 23455503
Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2013 | Pubmed ID: 23650378
Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors.
PloS one , 2013 | Pubmed ID: 23776545
Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis.
The Journal of biological chemistry Apr, 2014 | Pubmed ID: 24519940
Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll-like receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor.
Mucosal immunology Sep, 2015 | Pubmed ID: 25899687
Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis.
The Journal of clinical investigation Feb, 2016 | Pubmed ID: 26690704
The human milk oligosaccharide 2'-fucosyllactose attenuates the severity of experimental necrotising enterocolitis by enhancing mesenteric perfusion in the neonatal intestine.
The British journal of nutrition Oct, 2016 | Pubmed ID: 27609061
Enteroviruses infect human enteroids and induce antiviral signaling in a cell lineage-specific manner.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2017 | Pubmed ID: 28137842
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