Mayra Furlan-Magaril
Nuclear Dynamics Programme,
The Babraham Institute,
Nuclear Dynamics Programme, The Babraham Institute
Babraham Research Campus
Mayra is a molecular biologist specialized in epigenetics and genome architecture dedicated to understand how genome 3D conformation contributes to gene expression control and genomic stability.
Mayra studied her PhD at the UNAM in Mexico City investigating the function of a CTCF dependent insulator within the alfa-globin gene domain. As a postdoc Mayra became a fellow at the Babraham Institute in Cambridge, UK and continued to characterize structural components of the genome and their function.
Currently Mayra is a junior group leader at the Cellular Physiology Institute at the UNAM. Her research group is investigating the function of genome structure in gene expression control.
Neural stem cells in development and regenerative medicine.
Archives of medical research Nov-Dec, 2003 | Pubmed ID: 14734098
Globin genes transcriptional switching, chromatin structure and linked lessons to epigenetics in cancer: a comparative overview.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology Jul, 2007 | Pubmed ID: 17188536
Protection against telomeric position effects by the chicken cHS4 beta-globin insulator.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2007 | Pubmed ID: 17715059
Sequential chromatin immunoprecipitation protocol: ChIP-reChIP.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19378171
An insulator embedded in the chicken α-globin locus regulates chromatin domain configuration and differential gene expression.
Nucleic acids research Jan, 2011 | Pubmed ID: 20813760
The Krüppel-like factor 4 controls biosynthesis of thyrotropin-releasing hormone during hypothalamus development.
Molecular and cellular endocrinology Feb, 2011 | Pubmed ID: 21182892
Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes.
Nature structural & molecular biology Jun, 2011 | Pubmed ID: 21602820
Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter.
BMC cancer Jun, 2011 | Pubmed ID: 21663659
The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements.
Genome research Apr, 2015 | Pubmed ID: 25752748
Individual and Sequential Chromatin Immunoprecipitation Protocols.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 26404152
Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation.
Nature genetics Oct, 2017 | Pubmed ID: 28805829
Shaping Up the Embryo: The Role of Genome 3D Organization.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29564771
RNA proximity sequencing reveals the spatial organization of the transcriptome in the nucleus.
Nature biotechnology 07, 2019 | Pubmed ID: 31267103
RNA Interactions Are Essential for CTCF-Mediated Genome Organization.
Molecular cell 11, 2019 | Pubmed ID: 31522988
In situ dissection of domain boundaries affect genome topology and gene transcription in Drosophila.
Nature communications 02, 2020 | Pubmed ID: 32060283
The global and promoter-centric 3D genome organization temporally resolved during a circadian cycle.
Genome biology 06, 2021 | Pubmed ID: 34099014
Editorial: Chromatin Spatial Configuration and Function in Metazoans.
Frontiers in genetics , 2021 | Pubmed ID: 34456981
Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
Stefan Schoenfelder*,1,
Biola-Maria Javierre*,1,2,
Mayra Furlan-Magaril1,3,
Steven W. Wingett1,4,
Peter Fraser1,5
1Nuclear Dynamics Programme, The Babraham Institute, Babraham Research Campus,
2IJC Building, Campus ICO-Germans Trias i Pujol, Josep Carreras Leukemia Research Institute,
3Departamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México,
4Bioinformatics Group, The Babraham Institute, Babraham Research Campus,
5Department of Biological Science, Florida State University
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