Division of Neuroscience and Experimental Psychology,
School of Biological Sciences,
Manchester Academic Health Science Centre,
Lydia Becker Institute of Immunology and Inflammation,
Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Manchester Academic Health Science Centre
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Interleukin-1 and neuronal injury.
Nature reviews. Immunology Aug, 2005 | Pubmed ID: 16034365
The neurovascular unit and the key role of astrocytes in the regulation of cerebral blood flow.
Cerebrovascular diseases (Basel, Switzerland) , 2006 | Pubmed ID: 16374001
A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Mar, 2016 | Pubmed ID: 26661169
Interleukin-1 in Stroke: From Bench to Bedside.
Stroke 08, 2016 | Pubmed ID: 26931154
Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia.
Brain, behavior, and immunity Mar, 2017 | Pubmed ID: 27856349
Translational models for vascular cognitive impairment: a review including larger species.
BMC medicine 01, 2017 | Pubmed ID: 28118831
A quantitative brain map of experimental cerebral malaria pathology.
PLoS pathogens 03, 2017 | Pubmed ID: 28273147
Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro.
Stem cell research & therapy 04, 2017 | Pubmed ID: 28412968
Isolation and Cultivation of Primary Brain Endothelial Cells from Adult Mice.
Bio-protocol May, 2017 | Pubmed ID: 28603749
The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments).
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Nov, 2017 | Pubmed ID: 28797196
Boron-Based Inhibitors of the NLRP3 Inflammasome.
Cell chemical biology Nov, 2017 | Pubmed ID: 28943355
Assessing Inflammation in Acute Intracerebral Hemorrhage with PK11195 PET and Dynamic Contrast-Enhanced MRI.
Journal of neuroimaging : official journal of the American Society of Neuroimaging Mar, 2018 | Pubmed ID: 29064155
Acute high-fat feeding leads to disruptions in glucose homeostasis and worsens stroke outcome.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Jun, 2019 | Pubmed ID: 29171775
Microglial Priming as Trained Immunity in the Brain.
Neuroscience 05, 2019 | Pubmed ID: 29292078
Neutrophil infiltration to the brain is platelet-dependent, and is reversed by blockade of platelet GPIbα.
Immunology 06, 2018 | Pubmed ID: 29325217
Changes in the secretome of tri-dimensional spheroid-cultured human mesenchymal stem cells in vitro by interleukin-1 priming.
Stem cell research & therapy 01, 2018 | Pubmed ID: 29343288
SCIL-STROKE (Subcutaneous Interleukin-1 Receptor Antagonist in Ischemic Stroke): A Randomized Controlled Phase 2 Trial.
Stroke 05, 2018 | Pubmed ID: 29567761
Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses.
Scientific reports Apr, 2018 | Pubmed ID: 29618797
Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.
Clinical science (London, England : 1979) Apr, 2018 | Pubmed ID: 29712883
The therapeutic potential of the mesenchymal stem cell secretome in ischaemic stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Aug, 2018 | Pubmed ID: 29768965
Targeting the IL33-NLRP3 axis improves therapy for experimental cerebral malaria.
Proceedings of the National Academy of Sciences of the United States of America 07, 2018 | Pubmed ID: 29954866
Generation of Human Mesenchymal Stem Cell 3D Spheroids Using Low-binding Plates.
Bio-protocol Aug, 2018 | Pubmed ID: 30294619
Pentraxin 3 promotes long-term cerebral blood flow recovery, angiogenesis, and neuronal survival after stroke.
Journal of molecular medicine (Berlin, Germany) Dec, 2018 | Pubmed ID: 30315331
Small, Thin Graphene Oxide Is Anti-inflammatory Activating Nuclear Factor Erythroid 2-Related Factor 2 via Metabolic Reprogramming.
ACS nano Dec, 2018 | Pubmed ID: 30444603
Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons.
Brain, behavior, and immunity Feb, 2019 | Pubmed ID: 30453020
Using zebrafish larval models to study brain injury, locomotor and neuroinflammatory outcomes following intracerebral haemorrhage.
F1000Research , 2018 | Pubmed ID: 30473780
Stroke: The past, present and future.
Brain and neuroscience advances , 2018 | Pubmed ID: 30519643
Vascular dysfunction-The disregarded partner of Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 01, 2019 | Pubmed ID: 30642436
Ligature-induced periodontitis induces systemic inflammation but does not alter acute outcome after stroke in mice.
International journal of stroke : official journal of the International Stroke Society Feb, 2019 | Pubmed ID: 30794103
Extent of Ischemic Brain Injury After Thrombotic Stroke Is Independent of the NLRP3 (NACHT, LRR and PYD Domains-Containing Protein 3) Inflammasome.
Stroke May, 2019 | Pubmed ID: 31009361
1Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Manchester Academic Health Science Centre, University of Manchester,
2Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester,
3Lydia Becker Institute of Immunology and Inflammation, University of Manchester
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