Department of Surgery
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Regulatory T-cell compartmentalization and trafficking.
Blood Jul, 2006 | Pubmed ID: 16537800
Regulatory T cells, tumour immunity and immunotherapy.
Nature reviews. Immunology Apr, 2006 | Pubmed ID: 16557261
B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma.
The Journal of experimental medicine Apr, 2006 | Pubmed ID: 16606666
Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2006 | Pubmed ID: 16785496
Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis.
American journal of physiology. Cell physiology Mar, 2007 | Pubmed ID: 16943240
Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2007 | Pubmed ID: 17513719
Interleukin-2 administration alters the CD4+FOXP3+ T-cell pool and tumor trafficking in patients with ovarian carcinoma.
Cancer research Aug, 2007 | Pubmed ID: 17671219
Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma.
Cancer research Sep, 2007 | Pubmed ID: 17875732
Drugs designed to inhibit human p38 mitogen-activated protein kinase activation treat Toxoplasma gondii and Encephalitozoon cuniculi infection.
Antimicrobial agents and chemotherapy Dec, 2007 | Pubmed ID: 17923491
Inhibitory B7-family molecules in the tumour microenvironment.
Nature reviews. Immunology Jun, 2008 | Pubmed ID: 18500231
Tumor-induced immune suppression of in vivo effector T-cell priming is mediated by the B7-H1/PD-1 axis and transforming growth factor beta.
Cancer research Jul, 2008 | Pubmed ID: 18593946
Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2008 | Pubmed ID: 18802076
Cutting edge: IFN-gamma enables APC to promote memory Th17 and abate Th1 cell development.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2008 | Pubmed ID: 18941172
Endogenous IL-17 contributes to reduced tumor growth and metastasis.
Blood Jul, 2009 | Pubmed ID: 19289853
FOXP3 defines regulatory T cells in human tumor and autoimmune disease.
Cancer research May, 2009 | Pubmed ID: 19383912
Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments.
Blood Aug, 2009 | Pubmed ID: 19470694
Kupffer cell suppression of CD8+ T cells in human hepatocellular carcinoma is mediated by B7-H1/programmed death-1 interactions.
Cancer research Oct, 2009 | Pubmed ID: 19826049
Modeling dynamic changes in type 1 diabetes progression: quantifying beta-cell variation after the appearance of islet-specific autoimmune responses.
Mathematical biosciences and engineering : MBE Oct, 2009 | Pubmed ID: 19835428
Role of T cell TGFbeta signaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2009 | Pubmed ID: 19917689
Helicobacter pylori immune escape is mediated by dendritic cell-induced Treg skewing and Th17 suppression in mice.
Gastroenterology Mar, 2010 | Pubmed ID: 19931266
T(H)17 cells in tumour immunity and immunotherapy.
Nature reviews. Immunology Apr, 2010 | Pubmed ID: 20336152
Prognostic significance of regulatory T cells in tumor.
International journal of cancer Aug, 2010 | Pubmed ID: 20473951
A crucial role for host APCs in the induction of donor CD4+CD25+ regulatory T cell-mediated suppression of experimental graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2010 | Pubmed ID: 20810991
Th17 cells in cancer: help or hindrance?
Carcinogenesis May, 2011 | Pubmed ID: 21304053
T lymphocytes to IDO+ cells: check.
Blood Feb, 2011 | Pubmed ID: 21330479
IL-17+ regulatory T cells in the microenvironments of chronic inflammation and cancer.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2011 | Pubmed ID: 21357259
Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells.
International journal of cancer. Journal international du cancer Jan, 2012 | Pubmed ID: 21480217
Antigen-presenting cell (APC) subsets in ovarian cancer.
International reviews of immunology Apr-Jun, 2011 | Pubmed ID: 21557638
Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis.
Genes & development Jul, 2011 | Pubmed ID: 21764854
Dual biological effects of the cytokines interleukin-10 and interferon-γ.
Cancer immunology, immunotherapy : CII Nov, 2011 | Pubmed ID: 21918895
Deciphering the role of Th17 cells in human disease.
Trends in immunology Dec, 2011 | Pubmed ID: 21958759
Human TH17 cells are long-lived effector memory cells.
Science translational medicine Oct, 2011 | Pubmed ID: 21998407
Bone marrow and the control of immunity.
Cellular & molecular immunology Jan, 2012 | Pubmed ID: 22020068
Interleukin-10 ablation promotes tumor development, growth, and metastasis.
Cancer research Jan, 2012 | Pubmed ID: 22123924
Endogenous interleukin-10 constrains Th17 cells in patients with inflammatory bowel disease.
Journal of translational medicine Dec, 2011 | Pubmed ID: 22176654
The B7 homologues and their receptors in hematologic malignancies.
European journal of haematology Jun, 2012 | Pubmed ID: 22372959
Regulatory T cells in human ovarian cancer.
Journal of oncology , 2012 | Pubmed ID: 22481922
Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer.
Oncoimmunology Mar, 2012 | Pubmed ID: 22720236
Th17 cells have stem cell-like features and promote long-term immunity.
Oncoimmunology Jul, 2012 | Pubmed ID: 22754771
Nine lives for TH9s?
Nature medicine Aug, 2012 | Pubmed ID: 22869182
Elevated serum IL-8 is associated with the presence of hepatocellular carcinoma and independently predicts survival.
Cancer investigation Dec, 2012 | Pubmed ID: 23072563
T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment.
Current opinion in immunology Apr, 2013 | Pubmed ID: 23298609
Effects of tumor irradiation on host T-regulatory cells and systemic immunity in the context of adoptive T-cell therapy in mice.
Journal of immunotherapy (Hagerstown, Md. : 1997) Feb, 2013 | Pubmed ID: 23377667
NF-κB inhibits osteogenic differentiation of mesenchymal stem cells by promoting β-catenin degradation.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2013 | Pubmed ID: 23690607
Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2.
Immunity Sep, 2013 | Pubmed ID: 24012420
TLR2 mediates Helicobacter pylori-induced tolerogenic immune response in mice.
PloS one , 2013 | Pubmed ID: 24058595
Synbindin in Extracellular Signal-Regulated Protein Kinase Spatial Regulation and Gastric Cancer Aggressiveness.
Journal of the National Cancer Institute Oct, 2013 | Pubmed ID: 24104608
T cells and costimulation in cancer.
Cancer journal (Sudbury, Mass.) Nov-Dec, 2013 | Pubmed ID: 24270346
OCT1 is a determinant of synbindin-related ERK signalling with independent prognostic significance in gastric cancer.
Gut Jan, 2015 | Pubmed ID: 24717932
IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L.
Immunity May, 2014 | Pubmed ID: 24816405
TMEFF2 deregulation contributes to gastric carcinogenesis and indicates poor survival outcome.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2014 | Pubmed ID: 24987055
ArhGAP30 promotes p53 acetylation and function in colorectal cancer.
Nature communications Aug, 2014 | Pubmed ID: 25156493
MiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8.
Scientific reports Sep, 2014 | Pubmed ID: 25174450
Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells.
Gastroenterology Dec, 2014 | Pubmed ID: 25181692
Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancer.
Cancer research Dec, 2014 | Pubmed ID: 25277524
MiR-194 deregulation contributes to colorectal carcinogenesis via targeting AKT2 pathway.
Theranostics , 2014 | Pubmed ID: 25285168
Classification of current anticancer immunotherapies.
Oncotarget Dec, 2014 | Pubmed ID: 25537519
Myeloid cells in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) Oct, 2015 | Pubmed ID: 25914264
Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies.
Cancer immunology research Nov, 2015 | Pubmed ID: 26025381
Consensus nomenclature for CD8+ T cell phenotypes in cancer.
Oncoimmunology Apr, 2015 | Pubmed ID: 26137416
Dendritic cells are stressed out in tumor.
Cell research Sep, 2015 | Pubmed ID: 26227962
Chemokines and cellular plasticity of ovarian cancer stem cells.
Oncoscience , 2015 | Pubmed ID: 26328269
Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy.
Nature Nov, 2015 | Pubmed ID: 26503055
Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction.
Nature immunology Jan, 2016 | Pubmed ID: 26523864
PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer.
Cancer research Jan, 2016 | Pubmed ID: 26567139
Biological and pathological activities of interleukin-22.
Journal of molecular medicine (Berlin, Germany) 05, 2016 | Pubmed ID: 26923718
PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations.
Science translational medicine Mar, 2016 | Pubmed ID: 26936508
Hydrogel dual delivered celecoxib and anti-PD-1 synergistically improve antitumor immunity.
Oncoimmunology Feb, 2016 | Pubmed ID: 27057439
Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer.
Cell May, 2016 | Pubmed ID: 27133165
LncRNA GClnc1 Promotes Gastric Carcinogenesis and May Act as a Modular Scaffold of WDR5 and KAT2A Complexes to Specify the Histone Modification Pattern.
Cancer discovery 07, 2016 | Pubmed ID: 27147598
Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling.
Cancer research 06, 2016 | Pubmed ID: 27197152
Th22 cells control colon tumorigenesis through STAT3 and Polycomb Repression complex 2 signaling.
Oncoimmunology Aug, 2016 | Pubmed ID: 27622053
Inflammatory regulatory T cells in the microenvironments of ulcerative colitis and colon carcinoma.
Oncoimmunology Aug, 2016 | Pubmed ID: 27622054
Synthetic RORγ agonists regulate multiple pathways to enhance antitumor immunity.
Oncoimmunology , 2016 | Pubmed ID: 28123897
IL33 Promotes Colon Cancer Cell Stemness via JNK Activation and Macrophage Recruitment.
Cancer research 05, 2017 | Pubmed ID: 28249897
Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy.
Nature reviews. Immunology Sep, 2017 | Pubmed ID: 28555670
ARID1A-mutated ovarian cancers depend on HDAC6 activity.
Nature cell biology 08, 2017 | Pubmed ID: 28737768
Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy.
Cell Jul, 2017 | Pubmed ID: 28753429
Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor.
Nature immunology Dec, 2017 | Pubmed ID: 29083399
Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression.
The Journal of clinical investigation 12, 2017 | Pubmed ID: 29106384
Suppression of FIP200 and autophagy by tumor-derived lactate promotes naïve T cell apoptosis and affects tumor immunity.
Science immunology 11, 2017 | Pubmed ID: 29150439
Phenotype and tissue distribution of CD28H immune cell subsets.
Oncoimmunology , 2017 | Pubmed ID: 29209568
The Role of Tumor Microenvironment in Cancer Immunotherapy.
Advances in experimental medicine and biology , 2017 | Pubmed ID: 29275464
Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade-mediated tumor regression.
The Journal of clinical investigation 02, 2018 | Pubmed ID: 29337305
miR-508 Defines the Stem-like/Mesenchymal Subtype in Colorectal Cancer.
Cancer research 04, 2018 | Pubmed ID: 29374066
Mechanistic insights into cancer immunity and immunotherapy.
Cellular & molecular immunology May, 2018 | Pubmed ID: 29572549
Understanding the tumor immune microenvironment (TIME) for effective therapy.
Nature medicine 05, 2018 | Pubmed ID: 29686425
Priming of Adoptively Transferred T Cells with a RORγ Agonist Confers Durable Memory and Stemness .
Cancer research Jul, 2018 | Pubmed ID: 29769201
Human Naive T Cells Express Functional CXCL8 and Promote Tumorigenesis.
Journal of immunology (Baltimore, Md. : 1950) 07, 2018 | Pubmed ID: 29802127
Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer.
Cell metabolism Jul, 2018 | Pubmed ID: 29805099
Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer.
Cell 06, 2018 | Pubmed ID: 29906450
Tumor-infiltrating T cells in epithelial ovarian cancer: predictors of prognosis and biological basis of immunotherapy.
Gynecologic oncology 10, 2018 | Pubmed ID: 30243508
Spatial and phenotypic immune profiling of metastatic colon cancer.
JCI insight 11, 2018 | Pubmed ID: 30429368
Tracking Macrophage Infiltration in a Mouse Model of Pancreatic Cancer with the Positron Emission Tomography Tracer [11C]PBR28.
The Journal of surgical research 12, 2018 | Pubmed ID: 30463776
CD4+ Tissue-resident Memory T Cells Expand and Are a Major Source of Mucosal Tumour Necrosis Factor α in Active Crohn's Disease.
Journal of Crohn's & colitis Jul, 2019 | Pubmed ID: 30715262
CD8 T cells regulate tumour ferroptosis during cancer immunotherapy.
Nature May, 2019 | Pubmed ID: 31043744
RORγ Agonists Enhance the Sustained Antitumor Activity through Intrinsic Tc17 Cytotoxicity and Tc1 Recruitment.
Cancer immunology research Jul, 2019 | Pubmed ID: 31064778
Immunotherapy in Ovarian Cancer.
Surgical oncology clinics of North America Jul, 2019 | Pubmed ID: 31079799
Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy.
Cancer research May, 2019 | Pubmed ID: 31101760
Mathematical Modeling of the Metastatic Colorectal Cancer Microenvironment Defines the Importance of Cytotoxic Lymphocyte Infiltration and Presence of PD-L1 on Antigen Presenting Cells.
Annals of surgical oncology Jun, 2019 | Pubmed ID: 31250346
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