School of Biochemistry and Immunology,
Trinity Biomedical Sciences Institute,
School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute
Cliona O'Farrelly has not added Biography.
If you are Cliona O'Farrelly and would like to personalize this page please email our Author Liaison for assistance.
Induction of a novel chicken Toll-like receptor following Salmonella enterica serovar Typhimurium infection.
Infection and immunity Mar, 2006 | Pubmed ID: 16495540
Evolution, expression and effectiveness in a cluster of novel bovine beta-defensins.
Immunogenetics Apr, 2008 | Pubmed ID: 18369613
Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2008 | Pubmed ID: 18802051
Antigen stimulation of peripheral blood mononuclear cells from Mycobacterium bovis infected cattle yields evidence for a novel gene expression program.
BMC genomics Sep, 2008 | Pubmed ID: 18823559
Differential antimicrobial peptide gene expression patterns during early chicken embryological development.
Developmental and comparative immunology Apr, 2009 | Pubmed ID: 19007808
Toll-like receptor and antimicrobial peptide expression in the bovine endometrium.
Reproductive biology and endocrinology : RB&E Nov, 2008 | Pubmed ID: 19017375
Natural killer cells in obesity: impaired function and increased susceptibility to the effects of cigarette smoke.
PloS one Jan, 2010 | Pubmed ID: 20107494
Clinical anxiety, cortisol and interleukin-6: evidence for specificity in emotion-biology relationships.
Brain, behavior, and immunity Oct, 2010 | Pubmed ID: 20227485
Experimental Staphylococcus aureus infection of the mammary gland induces region-specific changes in innate immune gene expression.
Veterinary immunology and immunopathology Apr, 2011 | Pubmed ID: 21292330
Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion.
Hepatology (Baltimore, Md.) Jun, 2011 | Pubmed ID: 21452285
Activation of human invariant natural killer T cells with a thioglycoside analogue of α-galactosylceramide.
Clinical immunology (Orlando, Fla.) Aug, 2011 | Pubmed ID: 21493160
Risk factors for the development of depression in patients with hepatitis C taking interferon-α.
Neuropsychiatric disease and treatment , 2011 | Pubmed ID: 21654873
Preparation of pre-confluent retinal cells increases graft viability in vitro and in vivo: a mouse model.
PloS one , 2011 | Pubmed ID: 21738643
Ribavirin enhances IFN-α signalling and MxA expression: a novel immune modulation mechanism during treatment of HCV.
PloS one , 2011 | Pubmed ID: 22114715
Genome-wide transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis reveals suppression of host immune genes.
BMC genomics , 2011 | Pubmed ID: 22182502
Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production.
Immunity Sep, 2012 | Pubmed ID: 22981538
Global endometrial transcriptomic profiling: transient immune activation precedes tissue proliferation and repair in healthy beef cows.
BMC genomics , 2012 | Pubmed ID: 22985206
Hepatitis C virus targets the interferon-α JAK/STAT pathway by promoting proteasomal degradation in immune cells and hepatocytes.
FEBS letters May, 2013 | Pubmed ID: 23587486
CD141⁺ myeloid dendritic cells are enriched in healthy human liver.
Journal of hepatology Jan, 2014 | Pubmed ID: 23968887
Reply to: "Dendritic cell subset composition in the human liver is more complex than it seems".
Journal of hepatology May, 2014 | Pubmed ID: 24418016
Endogenous oils derived from human adipocytes are potent adjuvants that promote IL-1α-dependent inflammation.
Diabetes Jun, 2014 | Pubmed ID: 24458363
Characterisation and expression profile of the bovine cathelicidin gene repertoire in mammary tissue.
BMC genomics Feb, 2014 | Pubmed ID: 24524771
Hepatitis C virus (HCV)-induced suppressor of cytokine signaling (SOCS) 3 regulates proinflammatory TNF-α responses.
Journal of leukocyte biology Aug, 2014 | Pubmed ID: 24659790
IFNL cytokines do not modulate human or murine NK cell functions.
Human immunology Sep, 2014 | Pubmed ID: 24994459
In vitro blood cell responsiveness to IFN-α predicts clinical response independently of IL28B in hepatitis C virus genotype 1 infected patients.
Journal of translational medicine Jul, 2014 | Pubmed ID: 25048205
RNA-seq Transcriptional Profiling of Peripheral Blood Leukocytes from Cattle Infected with Mycobacterium bovis.
Frontiers in immunology , 2014 | Pubmed ID: 25206354
Tissue-specific NK cell populations and their origin.
Journal of leukocyte biology Dec, 2014 | Pubmed ID: 25246601
Anxiety is associated with higher levels of global DNA methylation and altered expression of epigenetic and interleukin-6 genes.
Psychiatric genetics Apr, 2015 | Pubmed ID: 25350786
The Role of microRNAs in Bovine Infection and Immunity.
Frontiers in immunology , 2014 | Pubmed ID: 25505900
Natural Killer Cells: Key Players in Endometriosis.
American journal of reproductive immunology (New York, N.Y. : 1989) Oct, 2015 | Pubmed ID: 26104509
Increased uNK Progenitor Cells in Women With Endometriosis and Infertility are Associated With Low Levels of Endometrial Stem Cell Factor.
American journal of reproductive immunology (New York, N.Y. : 1989) Apr, 2016 | Pubmed ID: 26791471
Myeloid Engraftment in Humanized Mice: Impact of Granulocyte-Colony Stimulating Factor Treatment and Transgenic Mouse Strain.
Stem cells and development Apr, 2016 | Pubmed ID: 26879149
CCR1 antagonism attenuates T cell trafficking to omentum and liver in obesity-associated cancer.
Immunology and cell biology 07, 2016 | Pubmed ID: 27046081
Liver immunology and its role in inflammation and homeostasis.
Cellular & molecular immunology 05, 2016 | Pubmed ID: 27063467
Sex-specific effects of TLR9 promoter variants on spontaneous clearance of HCV infection.
Gut 10, 2017 | Pubmed ID: 27196570
The microenvironment of visceral adipose tissue and liver alter natural killer cell viability and function.
Journal of leukocyte biology 12, 2016 | Pubmed ID: 27365528
Tissue-resident Eomes(hi) T-bet(lo) CD56(bright) NK cells with reduced proinflammatory potential are enriched in the adult human liver.
European journal of immunology 09, 2016 | Pubmed ID: 27485474
The CD4(+) T cell methylome contributes to a distinct CD4(+) T cell transcriptional signature in Mycobacterium bovis-infected cattle.
Scientific reports 08, 2016 | Pubmed ID: 27507428
Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 12, 2016 | Pubmed ID: 27617757
A novel anti-viral role for STAT3 in IFN-α signalling responses.
Cellular and molecular life sciences : CMLS 05, 2017 | Pubmed ID: 27988795
Early Subretinal Allograft Rejection Is Characterized by Innate Immune Activity.
Cell transplantation 06, 2017 | Pubmed ID: 28105976
Disease outcomes in a cohort of women in Ireland infected by hepatitis C-contaminated anti-D immunoglobulin during 1970s.
Journal of hepatology 12, 2017 | Pubmed ID: 28843656
Extratumoral PD-1 blockade does not perpetuate obesity-associated inflammation in esophageal adenocarcinoma.
Cancer letters 04, 2018 | Pubmed ID: 29339209
Uterine natural killer cell progenitor populations predict successful implantation in women with endometriosis-associated infertility.
American journal of reproductive immunology (New York, N.Y. : 1989) 03, 2018 | Pubmed ID: 29380456
Depleted polymorphonuclear leukocytes in human metastatic liver reflect an altered immune microenvironment associated with recurrent metastasis.
Cancer immunology, immunotherapy : CII 07, 2018 | Pubmed ID: 29572702
HIV-1 Promotes the Degradation of Components of the Type 1 IFN JAK/STAT Pathway and Blocks Anti-viral ISG Induction.
EBioMedicine Apr, 2018 | Pubmed ID: 29580840
Designer human tissue: coming to a lab near you.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Jul, 2018 | Pubmed ID: 29786548
Innate immunity in stem cell-derived hepatocytes.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Jul, 2018 | Pubmed ID: 29786555
Cervico-vaginal mucus (CVM) - an accessible source of immunologically informative biomolecules.
Veterinary research communications Dec, 2018 | Pubmed ID: 30117040
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses.
Nature immunology 12, 2018 | Pubmed ID: 30420624
Lactate-Mediated Acidification of Tumor Microenvironment Induces Apoptosis of Liver-Resident NK Cells in Colorectal Liver Metastasis.
Cancer immunology research Feb, 2019 | Pubmed ID: 30563827
β-Defensins: Farming the Microbiome for Homeostasis and Health.
Frontiers in immunology , 2018 | Pubmed ID: 30761155
Non-canonical Inflammasome-Mediated IL-1β Production by Primary Endometrial Epithelial and Stromal Fibroblast Cells Is NLRP3 and Caspase-4 Dependent.
Frontiers in immunology , 2019 | Pubmed ID: 30804935
The hepatitis C virus (HCV) protein, p7, suppresses inflammatory responses to tumor necrosis factor (TNF)-α signal transducer and activator of transcription (STAT)3 and extracellular signal-regulated kinase (ERK)-mediated induction of suppressor of cytokine signaling (SOCS)3.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2019 | Pubmed ID: 31163989
Balta Lucendo-Villarin1,
Hassan Rashidi1,2,
Sharmin Alhaque1,3,
Lena Fischer1,4,
Jose Meseguer-Ripolles1,
Yu Wang1,
Cliona O'Farrelly4,
Michael Themis3,
David C. Hay1
1MRC Centre for Regenerative Medicine, University of Edinburgh,
2UCL Great Ormond Street Institute of Child Health, University College London,
3Division of Biosciences, Department of Life Sciences, College of Health and Life Sciences, Brunel University London,
4School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin
关于 JoVE
版权所属 © 2024 MyJoVE 公司版权所有,本公司不涉及任何医疗业务和医疗服务。