Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics
Chun Han is an Assistant Professor in the Weill Institute for Cell and Molecular Biology and Department of Molecular Biology and Genetics, Cornell University in Ithaca, New York. He received his Bachelor of Science degree from Peking University, China, and a Ph.D. from University of Cincinnati, USA.
Dr. Han developed a great interest in studying cell biological questions using microscopy in genetically tractable model systems during his graduate and postdoctoral training. As a graduate student in Xinhua Lin’s lab at Cincinnati Children’s Hospital, he studied how morphogens form extracellular concentration gradients using Drosophila embryos and wing discs as model systems. Attracted by the beauty of Drosophila somatosensory neurons, he then moved to Yuh-Nung Jan’s lab at University of California, San Francisco to study dendrite biology. There he developed new tools to study interactions between sensory dendrites and nearby non-neural cells including glia and epidermal cells.
Dr. Han established his independent lab at Cornell University in 2014. His research interests are on extrinsic regulation of dendrite morphogenesis, the roles of neuron-phagocyte interactions in neurodegeneration, and development of cutting-edge genetic and imaging tools in Drosophila.
The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion.
eLife Mar, 2015 | Pubmed ID: 25764303
A Bitter Taste of the Sun Makes Egg-Laying Flies Run.
Genetics 02, 2017 | Pubmed ID: 28154195
Dendritic space-filling requires a neuronal type-specific extracellular permissive signal in .
Proceedings of the National Academy of Sciences of the United States of America 09, 2017 | Pubmed ID: 28874572
Ret and Substrate-Derived TGF-β Maverick Regulate Space-Filling Dendrite Growth in Drosophila Sensory Neurons.
Cell reports 08, 2018 | Pubmed ID: 30157422
Phosphatidylserine Externalization Results from and Causes Neurite Degeneration in Drosophila.
Cell reports 08, 2018 | Pubmed ID: 30157423
Robust CRISPR/Cas9-Mediated Tissue-Specific Mutagenesis Reveals Gene Redundancy and Perdurance in .
Genetics 02, 2019 | Pubmed ID: 30504366
Understanding human diseases using Drosophila.
Journal of genetics and genomics = Yi chuan xue bao 04, 2019 | Pubmed ID: 31056204
Die in pieces: How Drosophila sheds light on neurite degeneration and clearance.
Journal of genetics and genomics = Yi chuan xue bao 04, 2019 | Pubmed ID: 31080046
PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling.
Cell reports 05, 2019 | Pubmed ID: 31091453
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