Keiji Naruse

Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats.

Analysis of cyclic-stretching responses using cell-adhesion-patterned cells.

Application of a numerical simulation to improve the separation efficiency of a sperm sorter.

Impairment of leukocyte deformability in patients undergoing esophagectomy.

Stress-Axis Regulated Exon (STREX) in the C terminus of BK(Ca) channels is responsible for the stretch sensitivity.

The TRPV4 cation channel mediates stretch-evoked Ca2+ influx and ATP release in primary urothelial cell cultures.

Mechanical stretch stimulates integrin alphaVbeta3-mediated collagen expression in human anterior cruciate ligament cells.

Actin cytoskeleton regulates stretch-activated Ca2+ influx in human pulmonary microvascular endothelial cells.

Blastocyst quality scoring based on morphologic grading correlates with cell number.

Improved development of mouse and human embryos using a tilting embryo culture system.

A rapid microfluidic switching system for analysis at the single cellular level.

Effects of axial stretch on sarcolemmal BKCa channels in post-hatch chick ventricular myocytes.

[Musculoskeletal rehabilitation and bone. A novel approach to mechanotransduction using cell-adhesion-patterned cells].

Application of a microfluidic sperm sorter to the in-vitro fertilization of porcine oocytes reduced the incidence of polyspermic penetration.

In-vitro culture with a tilting device in chemically defined media during meiotic maturation and early development improves the quality of blastocysts derived from in-vitro matured and fertilized porcine oocytes.

Comparison between loose fragment chondrocytes and condyle fibrochondrocytes in cellular proliferation and redifferentiation.

Role of sarcolemmal BK(Ca) channels in stretch-induced extrasystoles in isolated chick hearts.

Microtubule dynamics regulate cyclic stretch-induced cell alignment in human airway smooth muscle cells.

The mechanical stimulation of cells in 3D culture within a self-assembling peptide hydrogel.

Screening of sperm velocity by fluid mechanical characteristics of a cyclo-olefin polymer microfluidic sperm-sorting device.

In situ imaging of the autonomous intracellular Ca(2+) oscillations of osteoblasts and osteocytes in bone.

Mechanical stretch increases the proliferation while inhibiting the osteogenic differentiation in dental pulp stem cells.

Ex vivo real-time observation of Ca(2+) signaling in living bone in response to shear stress applied on the bone surface.

Stretch-activated BK channel and heart function.

Rac1 recruitment to the archipelago structure of the focal adhesion through the fluid membrane as revealed by single-molecule analysis.

Detection of Micrococcus luteus biofilm formation in microfluidic environments by pH measurement using an ion-sensitive field-effect transistor.

Mechanobiology in cardiac physiology and diseases.

Effect of azelnidipine and amlodipine on single cell mechanics in mouse cardiomyocytes.

9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury.

TRPV2 is critical for the maintenance of cardiac structure and function in mice.

Load dependency in force-length relations in isolated single cardiomyocytes.

The neutral self-assembling peptide hydrogel SPG-178 as a topical hemostatic agent.

Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome.

Ca2+ influx and ATP release mediated by mechanical stretch in human lung fibroblasts.

Involvement of S1P1 receptor pathway in angiogenic effects of a novel adenosine-like nucleic acid analog COA-Cl in cultured human vascular endothelial cells.

A simple method for decreasing the liquid junction potential in a flow-through-type differential pH sensor probe consisting of pH-FETs by exerting spatiotemporal control of the liquid junction.

Transient receptor potential melastatin-4 is involved in hypoxia-reoxygenation injury in the cardiomyocytes.

Mechanical Stretch on Human Skin Equivalents Increases the Epidermal Thickness and Develops the Basement Membrane.

Induced NCX1 overexpression attenuates pressure overload-induced pathological cardiac remodelling.

[Response to mechanical stimulus and cardiovascular homeostasis.]

TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca concentration in mouse cardiomyocytes.

Effects of simulated ischemia on the transmural differences in the Frank-Starling relationship in isolated mouse ventricular cardiomyocytes.

Role of TRPC3 and TRPC6 channels in the myocardial response to stretch: Linking physiology and pathophysiology.

Mechano-sensitivity of mitochondrial function in mouse cardiac myocytes.

Effect of Oxidative Stress on Cardiovascular System in Response to Gravity.

The effects of load on transmural differences in contraction of isolated mouse ventricular cardiomyocytes.

Role of the TRPM4 Channel in Cardiovascular Physiology and Pathophysiology.

Human gingival fibroblast feeder cells promote maturation of induced pluripotent stem cells into cardiomyocytes.

MECHANOMEDICINE: applications of mechanobiology to medical sciences and next-generation medical technologies.

Cyclic stretch enhances reorientation and differentiation of 3-D culture model of human airway smooth muscle.

Mechanomedicine.

Stretching of single DNA molecules caused by accelerating flow on a microchip.

TRPV2 is required for mechanical nociception and the stretch-evoked response of primary sensory neurons.

L-type calcium channel modulates mechanosensitivity of the cardiomyocyte cell line H9c2.

Spiral Trajectory Modulation of Rheotaxic Motile Human Sperm in Cylindrical Microfluidic Channels of Different Inner Diameters.

Mechanical strain attenuates cytokine-induced ADAMTS9 expression via transient receptor potential vanilloid type 1.

Development of a model of ischemic heart disease using cardiomyocytes differentiated from human induced pluripotent stem cells.

Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure.

Increased hydrostatic pressure induces nuclear translocation of DAF-16/FOXO in C. elegans.