Department of Pediatric Oncology
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Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses.
Nature neuroscience Apr, 2009 | Pubmed ID: 19287388
A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2009 | Pubmed ID: 19458239
Sensory neuropathy attributable to loss of Bcl-w.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2011 | Pubmed ID: 21289171
Neuromuscular junction defects in mice with mutation of dynein heavy chain 1.
PloS one , 2011 | Pubmed ID: 21346813
Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2013 | Pubmed ID: 23516285
Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation.
The Journal of biological chemistry Sep, 2013 | Pubmed ID: 23867465
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities.
Nature medicine Nov, 2013 | Pubmed ID: 24076665
Shh-proteoglycan interactions regulate maturation of olfactory glomerular circuitry.
Developmental neurobiology Dec, 2014 | Pubmed ID: 24913191
The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis.
Developmental cell Apr, 2015 | Pubmed ID: 25816987
Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons.
Cell reports Oct, 2015 | Pubmed ID: 26489457
Emily J. Chadwick1,
David P. Yang1,
Mariella G. Filbin2,
Emanuele Mazzola3,
Yu Sun1,
Oded Behar1,4,
Maria F. Pazyra-Murphy1,
Liliana Goumnerova5,
Keith L. Ligon6,
Charles D. Stiles1,
Rosalind A. Segal1
1Department of Cancer Biology, Dana-Farber Cancer Institute,
2Department of Pediatrics, Children's Hospital,
3Department of Biostatistics & Computational Biology, Dana-Farber Cancer Institute,
4Department of Developmental Biology and Cancer Research, Hebrew University of Jerusalem,
5Department of Neurosurgery, Children's Hospital,
6Center for Molecular Oncologic Pathology, Department of Medical Oncology, Dana-Farber Cancer Institute
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