Yuan Li
Gastroenterology and Hepatology
Stanford University
Yuan-Na Lin is a Research Scholar in the Department of Oncology, Lombardi Cancer Center at Georgetown University School of Medicine, Washington DC. Dr. Lin is a board-certified visceral surgeon at University Hospital Hamburg-Eppendorf, Germany, where she has received her MD and Ph.D.
During her surgical residency, Dr. Lin has been working on the role of actin binding proteins in cancer cell development and metastasis in an interdisciplinary and translational approach. She has been focusing on the formins mDia1 and mDia3 in colon cancer metastasis and chromosomal instability by modulation of the cytoskeleton. She then moved to Georgetown University, Washington DC, USA, as a DFG (German Research Funding Organization) Research Scholar. Here, she set up an innovative 3D tumor spheroid co-culture platform to examine tumor cell – immune cell interactions, in order to reveal new resistance mechanisms towards T-cell mediated tumor cell killing.
As a clinician, Dr. Lin is particularly interested in bridging basic research with clinical application. Her ultimate goal is to improve immunotherapeutic treatment approaches in patients with pancreatic cancer.
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system.
Nature Nov, 2004 | Pubmed ID: 15510105
Hidden magnetic excitation in the pseudogap phase of a high-T(c) superconductor.
Nature Nov, 2010 | Pubmed ID: 21068838
Epigenetic reprogramming reverses the malignant epigenotype of the MMP/TIMP axis genes in tumor cells.
International journal of cancer Apr, 2014 | Pubmed ID: 24105737
Haplotyping germline and cancer genomes with high-throughput linked-read sequencing.
Nature biotechnology Mar, 2016 | Pubmed ID: 26829319
Multiplexed identification, quantification and genotyping of infectious agents using a semiconductor biochip.
Nature biotechnology 09, 2018 | Pubmed ID: 30010676
Testing Different Combinations of Acoustic Pressure and Doses of Quinolinic Acid for Induction of Focal Neuron Loss in Mice Using Transcranial Low-Intensity Focused Ultrasound.
Ultrasound in medicine & biology 01, 2019 | Pubmed ID: 30309748
Nonphagocytic Activation of NOX2 Is Implicated in Progressive Nonalcoholic Steatohepatitis During Aging.
Hepatology (Baltimore, Md.) 10, 2020 | Pubmed ID: 31950520
AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes.
The Journal of clinical investigation 08, 2020 | Pubmed ID: 32657776
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Autophagy Feb, 2021 | Pubmed ID: 33634751
Impact of macrophage differentiation on hematopoietic function enhancement by Shenzhu ErKang Syrup.
Aging Jan, 2024 | Pubmed ID: 38175693
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