Department of Pediatrics
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Expression pattern for unc5b, an axon guidance gene in embryonic zebrafish development.
Gene expression , 2007 | Pubmed ID: 17708418
Snrk-1 is involved in multiple steps of angioblast development and acts via notch signaling pathway in artery-vein specification in vertebrates.
Blood Jan, 2009 | Pubmed ID: 18723694
Syx, a RhoA guanine exchange factor, is essential for angiogenesis in Vivo.
Circulation research Sep, 2008 | Pubmed ID: 18757825
Dusp-5 and Snrk-1 coordinately function during vascular development and disease.
Blood Jan, 2009 | Pubmed ID: 18927432
Silencing of directional migration in roundabout4 knockdown endothelial cells.
BMC cell biology Nov, 2008 | Pubmed ID: 18980679
A whole-animal microplate assay for metabolic rate using zebrafish.
Journal of biomolecular screening Dec, 2008 | Pubmed ID: 19029015
Specific inhibition of cyclin-dependent kinase 5 activity induces motor neuron development in vivo.
Biochemical and biophysical research communications Aug, 2009 | Pubmed ID: 19523926
Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton.
Cell stress & chaperones Mar, 2010 | Pubmed ID: 19579057
A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo.
Blood Jan, 2010 | Pubmed ID: 19880500
Endothelial cell-specific chemotaxis receptor (ecscr) promotes angioblast migration during vasculogenesis and enhances VEGF receptor sensitivity.
Blood Jun, 2010 | Pubmed ID: 20086248
Nogo-B receptor is essential for angiogenesis in zebrafish via Akt pathway.
Blood Dec, 2010 | Pubmed ID: 20813898
Natural antisense transcript: a concomitant engagement with protein-coding transcript.
Oncotarget Oct, 2010 | Pubmed ID: 21311100
Fli+ etsrp+ hemato-vascular progenitor cells proliferate at the lateral plate mesoderm during vasculogenesis in zebrafish.
PloS one Feb, 2011 | Pubmed ID: 21364913
Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ₃.
Blood Aug, 2011 | Pubmed ID: 21636859
Sox factors transcriptionally regulate ROBO4 gene expression in developing vasculature in zebrafish.
The Journal of biological chemistry Sep, 2011 | Pubmed ID: 21730073
Reactive oxygen species driven angiogenesis by inorganic nanorods.
Nano letters Nov, 2011 | Pubmed ID: 21967244
Studies on Axenfeld-Rieger syndrome patients and mice reveal Foxc1's role in corneal neovascularization.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 22308435
Role of dual-specificity protein phosphatase-5 in modulating the myogenic response in rat cerebral arteries.
Journal of applied physiology (Bethesda, Md. : 1985) Jan, 2013 | Pubmed ID: 23172031
Endothelial cell-specific chemotaxis receptor (ECSCR) enhances vascular endothelial growth factor (VEGF) receptor-2/kinase insert domain receptor (KDR) activation and promotes proteolysis of internalized KDR.
The Journal of biological chemistry Apr, 2013 | Pubmed ID: 23393131
Protein structure in context: the molecular landscape of angiogenesis.
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology Jul-Aug, 2013 | Pubmed ID: 23868376
Mmp17b is essential for proper neural crest cell migration in vivo.
PloS one , 2013 | Pubmed ID: 24098510
SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplification caused by loss of polycystin-1.
Human molecular genetics Mar, 2014 | Pubmed ID: 24203696
Astrocytes directly influence tumor cell invasion and metastasis in vivo.
PloS one , 2013 | Pubmed ID: 24324647
Transcriptional inhibition of etv2 expression is essential for embryonic cardiac development.
Developmental biology Sep, 2014 | Pubmed ID: 24984259
Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism.
Biology open Dec, 2014 | Pubmed ID: 25505152
Protein expression, characterization and activity comparisons of wild type and mutant DUSP5 proteins.
BMC biochemistry Dec, 2014 | Pubmed ID: 25519881
Lipopolysaccharide (LPS)-mediated angiopoietin-2-dependent autocrine angiogenesis is regulated by NADPH oxidase 2 (Nox2) in human pulmonary microvascular endothelial cells.
The Journal of biological chemistry Feb, 2015 | Pubmed ID: 25568324
Organization for rare diseases India (ORDI) - addressing the challenges and opportunities for the Indian rare diseases' community.
Genetics research Aug, 2014 | Pubmed ID: 25579084
Delta-like 4 mRNA is regulated by adjacent natural antisense transcripts.
Vascular cell , 2015 | Pubmed ID: 25914805
SIGIRR genetic variants in premature infants with necrotizing enterocolitis.
Pediatrics Jun, 2015 | Pubmed ID: 25963006
RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells.
Journal of cell science 10, 2015 | Pubmed ID: 26136364
Gene Expression in Experimental Aortic Coarctation and Repair: Candidate Genes for Therapeutic Intervention?
PloS one , 2015 | Pubmed ID: 26207811
Identification of inhibitors that target dual-specificity phosphatase 5 provide new insights into the binding requirements for the two phosphate pockets.
BMC biochemistry Aug, 2015 | Pubmed ID: 26286528
Cystathionine β-synthase regulates endothelial function via protein S-sulfhydration.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jan, 2016 | Pubmed ID: 26405298
Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator (ECSCR) Regulates Lipolysis in White Adipocytes via the PTEN/AKT Signaling Pathway.
PloS one , 2015 | Pubmed ID: 26692198
Nogo-B receptor deficiency causes cerebral vasculature defects during embryonic development in mice.
Developmental biology Feb, 2016 | Pubmed ID: 26746789
The lncRNA PVT1 Contributes to the Cervical Cancer Phenotype and Associates with Poor Patient Prognosis.
PloS one , 2016 | Pubmed ID: 27232880
E-cadherin re-expression shows in vivo evidence for mesenchymal to epithelial transition in clonal metastatic breast tumor cells.
Oncotarget Jul, 2016 | Pubmed ID: 27270319
Critical Role of the Secondary Binding Pocket in Modulating the Enzymatic Activity of DUSP5 toward Phosphorylated ERKs.
Biochemistry Nov, 2016 | Pubmed ID: 27739308
Sucrose Nonfermenting-Related Kinase Enzyme-Mediated Rho-Associated Kinase Signaling is Responsible for Cardiac Function.
Circulation. Cardiovascular genetics Dec, 2016 | Pubmed ID: 27780848
Dual Specificity Phosphatase 5 Is Essential for T Cell Survival.
PloS one , 2016 | Pubmed ID: 27936095
Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor.
BMC biochemistry 05, 2017 | Pubmed ID: 28569147
miRNA-Mediated RNA Activation in Mammalian Cells.
Advances in experimental medicine and biology , 2017 | Pubmed ID: 28639193
Sucrose Non-Fermenting Related Kinase Expression in Ovarian Cancer and Correlation with Clinical Features.
Cancer investigation Aug, 2017 | Pubmed ID: 28722495
SNRK (Sucrose Nonfermenting 1-Related Kinase) Promotes Angiogenesis In Vivo.
Arteriosclerosis, thrombosis, and vascular biology 02, 2018 | Pubmed ID: 29242271
Cystathionine β-Synthase Is Necessary for Axis Development .
Frontiers in cell and developmental biology , 2018 | Pubmed ID: 29503817
Temporal and Spatial Post-Transcriptional Regulation of Zebrafish mRNA by Long Noncoding RNA During Brain Vascular Assembly.
Arteriosclerosis, thrombosis, and vascular biology 07, 2018 | Pubmed ID: 29724820
Corrigendum: Cystathionine β-Synthase Is Necessary for Axis Development .
Frontiers in cell and developmental biology , 2018 | Pubmed ID: 30310813
Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish ( Danio rerio).
Arteriosclerosis, thrombosis, and vascular biology 12, 2018 | Pubmed ID: 30571172
Lessons learned from a lncRNA odyssey for two genes with vascular functions, DLL4 and TIE1.
Vascular pharmacology 03, 2019 | Pubmed ID: 30910126
Interaction of tumor cells and astrocytes promotes breast cancer brain metastases through TGF-β2/ANGPTL4 axes.
NPJ precision oncology , 2019 | Pubmed ID: 31602400
Cardiomyocyte-Specific Prevents Inflammation in the Heart.
Journal of the American Heart Association 11, 2019 | Pubmed ID: 31718444
Discovery and Characterization of Halogenated Xanthene Inhibitors of DUSP5 as Potential Photodynamic Therapeutics.
Journal of photochemistry and photobiology. A, Chemistry Apr, 2019 | Pubmed ID: 31839699
miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer.
Cell reports 12, 2019 | Pubmed ID: 31875548
ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis.
Oncogene 04, 2020 | Pubmed ID: 32029900
Hepatic Vein Blood Increases Lung Microvascular Angiogenesis and Endothelial Cell Survival-Toward an Understanding of Univentricular Circulation.
Seminars in thoracic and cardiovascular surgery Winter, 2020 | Pubmed ID: 32387780
Rapamycin treatment correlates changes in primary cilia expression with cell cycle regulation in epithelial cells.
Biochemical pharmacology 08, 2020 | Pubmed ID: 32470549
Astrocytes influence medulloblastoma phenotypes and CD133 surface expression.
PloS one , 2020 | Pubmed ID: 32628717
Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2.
Science advances 07, 2020 | Pubmed ID: 32937467
SNRK: a metabolic regulator with multifaceted role in development and disease.
Vessel plus , 2020 | Pubmed ID: 32968716
Peritoneal Spread of Ovarian Cancer Harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling.
Cancer research 12, 2020 | Pubmed ID: 33087324
DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling.
Scientific reports 12, 2020 | Pubmed ID: 33318551
Established, New and Emerging Concepts in Brain Vascular Development.
Frontiers in physiology , 2021 | Pubmed ID: 33643074
sVEGFR1 Is Enriched in Hepatic Vein Blood-Evidence for a Provisional Hepatic Factor Candidate?
Frontiers in pediatrics , 2021 | Pubmed ID: 34195162
The Yin and the Yang of Transformative Research During the COVID-19 Pandemic-A Perspective.
Frontiers in pediatrics , 2021 | Pubmed ID: 34249804
RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
Cell reports 11, 2021 | Pubmed ID: 34731628
Editorial: Molecular Mechanisms and Signaling in Endothelial Cell Biology and Vascular Heterogeneity.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 34977049
Cilia proteins are biomarkers of altered flow in the vasculature.
JCI insight 03, 2022 | Pubmed ID: 35143420
Coagulation Factor IIIa () Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype.
Frontiers in cell and developmental biology , 2022 | Pubmed ID: 35386206
Ciliogenesis mechanisms mediated by PAK2-ARL13B signaling in brain endothelial cells is responsible for vascular stability.
Biochemical pharmacology 08, 2022 | Pubmed ID: 35700757
Zain Zaki Zakaria1,2,
Shahram Eisa-Beygi3,
Fatiha M. Benslimane1,
Ramani Ramchandran4,
Huseyin C. Yalcin1
1Biomedical Research Center, Qatar University, Doha, Qatar,
2Department of Biological and Environmental Sciences, College of Arts and Science, Qatar University, Doha, Qatar,
3Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin,
4Department of Pediatrics, Medical College of Wisconsin
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