Martin Schmelz

Interleukin-6 in combination with its soluble IL-6 receptor sensitises rat skin nociceptors to heat, in vivo.

Prostaglandin E2 induces vasodilation and pruritus, but no protein extravasation in atopic dermatitis and controls.

ATP responses in human C nociceptors.

Sensitivity of human scalp skin to pruritic stimuli investigated by intradermal microdialysis in vivo.

Neural signal processing: the underestimated contribution of peripheral human C-fibers.

Pathological C-fibres in patients with a chronic painful condition.

Itch.

The effect of the nitric oxide synthase inhibitor N-nitro-L-arginine-methyl ester on neuropeptide-induced vasodilation and protein extravasation in human skin.

Differential modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by S-ketamine and clonidine in humans.

Central origin of secondary mechanical hyperalgesia.

Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin.

Substance-P-induced protein extravasation is bilaterally increased in complex regional pain syndrome.

Proinflammatory role of proteinase-activated receptor-2 in humans and mice during cutaneous inflammation in vivo.

Short-term infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal.

Naloxone provokes similar pain facilitation as observed after short-term infusion of remifentanil in humans.

Neuronal sensitization for histamine-induced itch in lesional skin of patients with atopic dermatitis.

Neurophysiology of pruritus: cutaneous elicitation of itch.

Neurophysiology of pruritus: interaction of itch and pain.

Modern aspects of cutaneous neurogenic inflammation.

No alpha-adrenoreceptor-induced C-fiber activation in healthy human skin.

Effects of gender and level of surgical sympathetic block on vasoconstrictor function.

Differential effects of surgical sympathetic block at the T2 and T4 level on vasoconstrictor function.

Opioid-induced mast cell activation and vascular responses is not mediated by mu-opioid receptors: an in vivo microdialysis study in human skin.

Electrically stimulated axon reflexes are diminished in diabetic small fiber neuropathies.

Perioperative intravenous lidocaine has preventive effects on postoperative pain and morphine consumption after major abdominal surgery.

High local concentrations and effects on differentiation implicate interleukin-6 as a paracrine regulator.

Facilitated neurogenic inflammation in unaffected limbs of patients with complex regional pain syndrome.

The cyclooxygenase isozyme inhibitors parecoxib and paracetamol reduce central hyperalgesia in humans.

Mechanically induced axon reflex and hyperalgesia in human UV-B burn are reduced by systemic lidocaine.

Catecholamine release in human skin--a microdialysis study.

Neural activation during experimental allodynia: a functional magnetic resonance imaging study.

Sensitization to bradykinin B1 and B2 receptor activation in UV-B irradiated human skin.

Chemically and electrically induced sweating and flare reaction.

The effect of intravenous infusion of adenosine on electrically evoked hyperalgesia in a healthy volunteer model of central sensitization.

Electrically evoked itch in humans.

Transcutaneous penetration of toluene in rat skin a microdialysis study.

Altered central excitability and analgesic treatment in patients with restless legs syndrome.

Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skin.

Different profiles of buprenorphine-induced analgesia and antihyperalgesia in a human pain model.

Activation of naloxone-sensitive and -insensitive inhibitory systems in a human pain model.

Itch and pain.

Neurogenic components of trypsin- and thrombin-induced inflammation in rat skin, in vivo.

Angiotensin converting enzyme has an inhibitory role in CGRP metabolism in human skin.

Duration of effects of aspirin on platelet function in healthy volunteers: an analysis using the PFA-100.

Pathophysiology and treatment of pain in joint disease.

Frontiers in pruritus research: scratching the brain for more effective itch therapy.

Chronic itch and pain--similarities and differences.

Reduction of pulmonary edema by short-acting local anesthetics.

The neurobiology of itch.

Delta-9-THC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief.

Bradykinin is a potent pruritogen in atopic dermatitis: a switch from pain to itch.

Neurophysiological, neuroimmunological, and neuroendocrine basis of pruritus.

Catecholamine-induced excitation of nociceptors in sympathetically maintained pain.

Modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by parecoxib in humans.

Abnormal function of C-fibers in patients with diabetic neuropathy.

Potentiation of nociceptive responses to low pH injections in humans by prostaglandin E2.

Monocyte chemoattractant protein-1 in subcutaneous abdominal adipose tissue: characterization of interstitial concentration and regulation of gene expression by insulin.

The impact of opioid-induced hyperalgesia for postoperative pain.

Opioids and the skin: "itchy" perspectives beyond analgesia and abuse.

Differential sensitivity of thick and thin fibers to HIV and therapy-induced neuropathy.

Rapid flare development evoked by current frequency-dependent stimulation analyzed by full-field laser perfusion imaging.

Clinical classification of itch: a position paper of the International Forum for the Study of Itch.

Nociceptor sensitization to mechanical and thermal stimuli in pig skin in vivo.

Endothelin 1 activates and sensitizes human C-nociceptors.

Representation of UV-B-induced thermal and mechanical hyperalgesia in the human brain: a functional MRI study.

A subpopulation of capsaicin-sensitive porcine dorsal root ganglion neurons is lacking hyperpolarization-activated cyclic nucleotide-gated channels.

Neuropeptides, neurogenic inflammation and complex regional pain syndrome (CRPS).

Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury.

Separate peripheral pathways for pruritus in man.

Facilitated neurotrophin release in sensitized human skin.

In situ profiling of adipokines in subcutaneous microdialysates from lean and obese individuals.

Chapter 18 Itch and cold allodynia.

Chapter 29 Microneurography in the assessment of neuropathic pain.

Painful and nonpainful phantom and stump sensations in acute traumatic amputees.

Itch and pain.

Differential endogenous pain modulation in complex-regional pain syndrome.

Neural fractalkine expression is closely linked to pain and pancreatic neuritis in human chronic pancreatitis.

Translating nociceptive processing into human pain models.

Post-junctional facilitation of Substance P signaling in a tibia fracture rat model of complex regional pain syndrome type I.

How pain becomes itch.

Predominant CB2 receptor expression in endothelial cells of glioblastoma in humans.

Hematopoietic colony-stimulating factors mediate tumor-nerve interactions and bone cancer pain.

Long-acting local anesthetics attenuate FMLP-induced acute lung injury in rats.

Single-fiber recordings of unmyelinated afferents in pig.

Acute hyperinsulinemia differentially regulates interstitial and circulating adiponectin oligomeric pattern in lean and insulin-resistant, obese individuals.

Patterns of activity-dependent conduction velocity changes differentiate classes of unmyelinated mechano-insensitive afferents including cold nociceptors, in pig and in human.

Neurotrophins in the cerebrospinal fluid of patient cohorts with neuropathic pain, nociceptive pain, or normal pressure hydrocephalus.

Pain: itch without pain-a labeled line for itch sensation?

NGF induces non-inflammatory localized and lasting mechanical and thermal hypersensitivity in human skin.

Nerve growth factor-evoked nociceptor sensitization in pig skin in vivo.

Thoracoscopic sympathectomy at the T2 or T3 level facilitates bradykinin-induced protein extravasation in human forearm skin.

Experimental thermal lesions induce beta-thromboglobulin release from activated platelets.

Pituitary adenylate cyclase activating polypeptide: an important vascular regulator in human skin in vivo.

Electrically induced quantitative sudomotor axon reflex test in human volunteers.

Pathogenesis of pruritus.

Differential central pain processing following repetitive intramuscular proton/prostaglandin Eâ‚‚ injections in female fibromyalgia patients and healthy controls.

Chimpanzees know that others make inferences.

Effects of COX inhibition on experimental pain and hyperalgesia during and after remifentanil infusion in humans.

Time course of acetylcholine-induced activation of sympathetic efferents matches axon reflex sweating in humans.

NGF enhances electrically induced pain, but not axon reflex sweating.

Neuronal sensitivity of the skin.

Structural and functional differences between neuropathy with and without pain?

Nerve growth factor selectively decreases activity-dependent conduction slowing in mechano-insensitive C-nociceptors.

A study of serum concentrations and dermal levels of NGF in atopic dermatitis and healthy subjects.

Does spontaneous activity in C-nociceptors provide a readout to quantify neuropathic pain?

Double spikes to single electrical stimulation correlates to spontaneous activity of nociceptors in painful neuropathy patients.