Ru Zhang

Development of a high-throughput assay for screening of gamma-secretase inhibitor with endogenous human, mouse or Drosophila gamma-secretase.

Intact MDM2 E3 ligase activity is required for the cytosolic localization and function of β-arrestin2.

Magnesium Lithospermate B Protects Cardiomyocytes from Ischemic Injury Via Inhibition of TAB1-p38 Apoptosis Signaling.

Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells.

Tools for GPCR drug discovery.

Novel object recognition as a facile behavior test for evaluating drug effects in AβPP/PS1 Alzheimer's disease mouse model.

Stress-mediated p38 activation promotes somatic cell reprogramming.

Proliferation rate of somatic cells affects reprogramming efficiency.

iPSCs and small molecules: a reciprocal effort towards better approaches for drug discovery.

Preclinical and clinical studies of unrelieved aural fullness following intratympanic gentamicin injection in patients with intractable Ménière's disease.

Identification of a novel small-molecule agonist for human G protein-coupled receptor 3.

Small molecule compound induces chromatin de-condensation and facilitates induced pluripotent stem cell generation.

Methuselah regulates longevity via dTOR: a pathway revealed by small-molecule ligands.

CXCR4 activation promotes differentiation of human embryonic stem cells to neural stem cells.

One-step generation of mice carrying a conditional allele together with an HA-tag insertion for the delta opioid receptor.

BLT1 in dendritic cells promotes Th1/Th17 differentiation and its deficiency ameliorates TNBS-induced colitis.

Deficiency of β-Arrestin 2 in Dendritic Cells Contributes to Autoimmune Diseases.

Donepezil, a drug for Alzheimer's disease, promotes oligodendrocyte generation and remyelination.

Development of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of Drugs.

Baicalein inhibits SARS-CoV-2/VSV replication with interfering mitochondrial oxidative phosphorylation in a mPTP dependent manner.

Neonatal cortical astrocytes possess intrinsic potential in neuronal conversion in defined media.

Risk Factors of Difficult Pharyngeal Accidental Fishbones Ingestion.

Epiphycan Predicts Poor Outcomes and Promotes Metastasis in Ovarian Cancer.

Chlorzoxazone Alleviates Experimental Autoimmune Encephalomyelitis via Inhibiting IL-6 Secretion of Dendritic Cells.

Amelioration of Experimental Autoimmune Encephalomyelitis in Alzheimer's Disease Mouse Models: A Potential Role for Aβ.

TGFβR-1/ALK5 inhibitor RepSox induces enteric glia-to-neuron transition and influences gastrointestinal mobility in adult mice.

Multi-channel AgNWs-doped interdigitated organic electrochemical transistors enable sputum-based device towards noninvasive and portable diagnosis of lung cancer.