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A public-private consortium advances cardiac safety evaluation: achievements of the HESI Cardiac Safety Technical Committee.
Journal of pharmacological and toxicological methods , 2013 | Pubmed ID: 23567075
The Comprehensive in Vitro Proarrhythmia Assay (CiPA) initiative - Update on progress.
Journal of pharmacological and toxicological methods , 2016 | Pubmed ID: 27282641
Non-Lethal Endotoxin Injection: A Rat Model of Hypercoagulability.
PloS one , 2017 | Pubmed ID: 28081568
Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study.
Toxicological sciences : an official journal of the Society of Toxicology 08, 2018 | Pubmed ID: 29718449
International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment.
Cell reports Sep, 2018 | Pubmed ID: 30257217
Electrophysiological characterization of drug response in hSC-derived cardiomyocytes using voltage-sensitive optical platforms.
Journal of pharmacological and toxicological methods , 2019 | Pubmed ID: 31319140
Considerations for an , Cell-Based Testing Platform for Detection of Adverse Drug-Induced Inotropic Effects in Early Drug Development. Part 1: General Considerations for Development of Novel Testing Platforms.
Frontiers in pharmacology , 2019 | Pubmed ID: 31447679
Considerations for an , Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes.
Frontiers in pharmacology , 2019 | Pubmed ID: 31555128
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
Scientific reports , | Pubmed ID: 32221320
Echocardiographic and hemodynamic indices of myocardial contractility simultaneously evaluated in telemetered beagle dogs: A HESI-sponsored cross-company evaluation.
Journal of pharmacological and toxicological methods Sep, 2020 | Pubmed ID: 32663523
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells.
Scientific reports , | Pubmed ID: 32665705
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations.
Regulatory toxicology and pharmacology : RTP , | Pubmed ID: 32822771
Use of the ZDF rat to model dietary fat induced hypercoagulability is limited by progressive and fatal nephropathy.
Journal of pharmacological and toxicological methods , 2021 | Pubmed ID: 33122074
Can We Panelize Seizure?
Toxicological sciences : an official journal of the Society of Toxicology Jan, 2021 | Pubmed ID: 33165543
The Challenges of Predicting Drug-Induced QTc Prolongation in Humans.
Toxicological sciences : an official journal of the Society of Toxicology Apr, 2022 | Pubmed ID: 35148401
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