Departments of Physiology and Neurobiology
Eiji Shigetomi has not added Biography.
If you are Eiji Shigetomi and would like to personalize this page please email our Author Liaison for assistance.
Analysis of the molecular mechanisms controlling synaptic transmission by patch-clamp recording in brainstem slices.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica Apr, 2003 | Pubmed ID: 12777844
Differential increases in P2X receptor levels in rat vagal efferent neurones following a vagal nerve section.
Brain research Jul, 2003 | Pubmed ID: 12788520
ATP- and adenosine-mediated signaling in the central nervous system: synaptic purinoceptors: the stage for ATP to play its "dual-role".
Journal of pharmacological sciences Feb, 2004 | Pubmed ID: 14978346
Action potential-independent release of glutamate by Ca2+ entry through presynaptic P2X receptors elicits postsynaptic firing in the brainstem autonomic network.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2004 | Pubmed ID: 15044552
A dual-role played by extracellular ATP in frequency-filtering of the nucleus Tractus solitarii network.
Advances in experimental medicine and biology , 2004 | Pubmed ID: 15602957
Blocker-resistant presynaptic voltage-dependent Ca2+ channels underlying glutamate release in mice nucleus tractus solitarii.
Brain research Aug, 2006 | Pubmed ID: 16814754
Facilitation of spontaneous glycine release by anoxia potentiates NMDA receptor current in the hypoglossal motor neurons of the rat.
The European journal of neuroscience Mar, 2007 | Pubmed ID: 17408431
[Purinergic regulatory complex in the brain synapses].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology Jun, 2007 | Pubmed ID: 17633523
Tracking transmitter-gated P2X cation channel activation in vitro and in vivo.
Nature methods Jan, 2008 | Pubmed ID: 18084300
Two forms of astrocyte calcium excitability have distinct effects on NMDA receptor-mediated slow inward currents in pyramidal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2008 | Pubmed ID: 18579739
A genetically targeted optical sensor to monitor calcium signals in astrocyte processes.
Nature neuroscience Jun, 2010 | Pubmed ID: 20495558
Monitoring astrocyte calcium microdomains with improved membrane targeted GCaMP reporters.
Neuron glia biology Dec, 2010 | Pubmed ID: 21205365
Bulk loading of calcium indicator dyes to study astrocyte physiology: key limitations and improvements using morphological maps.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2011 | Pubmed ID: 21697385
[Synaptic regulation by astrocytes].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica Oct, 2011 | Pubmed ID: 21986065
Neuronal P2X2 receptors are mobile ATP sensors that explore the plasma membrane when activated.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2011 | Pubmed ID: 22090499
TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3.
Nature neuroscience Jan, 2012 | Pubmed ID: 22158513
Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses.
The Journal of general physiology May, 2013 | Pubmed ID: 23589582
Müller cell-mediated neurite outgrowth of the retinal ganglion cells via P2Y receptor signals.
Journal of neurochemistry Feb, 2016 | Pubmed ID: 26560804
Probing the Complexities of Astrocyte Calcium Signaling.
Trends in cell biology Apr, 2016 | Pubmed ID: 26896246
Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain.
The Journal of clinical investigation May, 2016 | Pubmed ID: 27064281
The Clock mutant mouse is a novel experimental model for nocturia and nocturnal polyuria.
Neurourology and urodynamics Apr, 2017 | Pubmed ID: 27348079
Urothelial ATP exocytosis: regulation of bladder compliance in the urine storage phase.
Scientific reports 07, 2016 | Pubmed ID: 27412485
Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa.
PloS one , 2017 | Pubmed ID: 28060940
P2Y-deficiency increases micturition frequency and attenuates sustained contractility of the urinary bladder in mice.
Scientific reports 04, 2017 | Pubmed ID: 28396595
Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y Receptor Downregulation.
Cell reports 05, 2017 | Pubmed ID: 28494865
Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway.
Nature communications 06, 2017 | Pubmed ID: 28642575
Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence.
Neuron Aug, 2017 | Pubmed ID: 28712653
The Circadian expression of Piezo1, TRPV4, Connexin26, and VNUT, associated with the expression levels of the clock genes in mouse primary cultured urothelial cells.
Neurourology and urodynamics 03, 2018 | Pubmed ID: 28881406
Author Correction: Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway.
Nature communications 11, 2017 | Pubmed ID: 29138397
Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca Dynamics in Astrocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 02, 2018 | Pubmed ID: 29305530
Aberrant astrocyte Ca signals "AxCa signals" exacerbate pathological alterations in an Alexander disease model.
Glia 05, 2018 | Pubmed ID: 29383757
The oscillation of intracellular Ca influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium.
Scientific reports 04, 2018 | Pubmed ID: 29632308
Anti-Depressant Fluoxetine Reveals its Therapeutic Effect Via Astrocytes.
EBioMedicine Jun, 2018 | Pubmed ID: 29887330
The time-dependent variation of ATP release in mouse primary-cultured urothelial cells is regulated by the clock gene.
Neurourology and urodynamics 11, 2018 | Pubmed ID: 30106187
Aberrant Calcium Signals in Reactive Astrocytes: A Key Process in Neurological Disorders.
International journal of molecular sciences Feb, 2019 | Pubmed ID: 30823575
Intermittent restraint stress induces circadian misalignment in the mouse bladder, leading to nocturia.
Scientific reports 07, 2019 | Pubmed ID: 31296902
Author Correction: Intermittent restraint stress induces circadian misalignment in the mouse bladder, leading to nocturia.
Scientific reports Nov, 2019 | Pubmed ID: 31700120
Reactive astrocyte-driven epileptogenesis is induced by microglia initially activated following status epilepticus.
JCI insight 05, 2021 | Pubmed ID: 33830944
Different effects of GsMTx4 on nocturia associated with the circadian clock and Piezo1 expression in mice.
Life sciences Aug, 2021 | Pubmed ID: 33930366
Transnasal transplantation of human induced pluripotent stem cell-derived microglia to the brain of immunocompetent mice.
Glia 10, 2021 | Pubmed ID: 34309082
Adenosine A receptor down-regulates metabotropic glutamate receptor 5 in astrocytes during postnatal development.
Glia 11, 2021 | Pubmed ID: 34339538
Abnormal Ca Signals in Reactive Astrocytes as a Common Cause of Brain Diseases.
International journal of molecular sciences Dec, 2021 | Pubmed ID: 35008573
Effects of fatty acid metabolites on nocturia.
Scientific reports 02, 2022 | Pubmed ID: 35197540
Transient astrocytic mGluR5 expression drives synaptic plasticity and subsequent chronic pain in mice.
The Journal of experimental medicine 04, 2022 | Pubmed ID: 35319723
1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi,
2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi,
3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi,
4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo
关于 JoVE
版权所属 © 2024 MyJoVE 公司版权所有,本公司不涉及任何医疗业务和医疗服务。